TIPS置入术后不常规进行多普勒随访。16年的单中心经验。

4区 医学 Q3 Medicine Netherlands Journal of Medicine Pub Date : 2020-12-01
K de Wit, O M van Delden, U Beuers, R B Takkenberg
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引用次数: 0

摘要

背景与目的:经颈静脉肝内门静脉系统分流术(TIPS)是治疗门静脉高压症并发症的有效干预手段。自引入聚四氟乙烯(PTFE)覆盖支架以来,TIPS的通畅率有所提高,常规TIPS监测的必要性已成为问题。本研究的目的是评估在某学术中心接受TIPS的患者的适应症、临床结果、生存率和多普勒超声随访率。方法:一项回顾性队列研究,纳入2001年至2016年期间接受ptfe覆盖TIPS放置的所有连续成年患者。对临床、生化和影像学结果进行回顾和分析。结果:共纳入103例患者进行分析。随访1年,91%的患者成功控制出血(41/45),80%的患者成功控制难治性腹水(8/10)。在静脉曲张出血患者中,较高的MELD评分是90天死亡率(HR 1.28 /分,p < 0.001)和1年死亡率(HR 1.24 /分,p < 0.001)的危险因素。在难治性腹水患者中,较高的MELD评分仅是90天死亡率的一个危险因素(HR 1.13 /分,p = 0.03)。随访期间多普勒超声检查发现4%(6/166)的患者出现异常,均伴有临床恶化,而11.4%(19/166)的患者出现TIPS功能障碍的临床症状。结论:在ptfe覆盖的TIPS放置后,常规多普勒超声随访似乎是不必要的,因为它的发生率很低,异常的多普勒结果几乎总是与TIPS功能障碍的临床症状相关。
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Doppler follow-up after TIPS placement is not routinely indicated. A 16-years single centre experience.

Background and aims: Transjugular intrahepatic portosystemic shunt (TIPS) is an effective intervention to treat complications of portal hypertension. Since the introduction of polytetrafluoroethylene (PTFE)-covered stents, TIPS patency rates have improved, and the need for routine TIPS surveillance has become questionable. Aims of this study were to assess the indications, clinical outcome and survival, and yield of Doppler ultrasound follow-up in patients who received a TIPS in an academic centre.

Methods: A retrospective cohort study of all adult consecutive patients who underwent PTFE-covered TIPS placement between 2001 and 2016. Clinical, biochemical, and imaging findings were reviewed and analysed.

Results: A total of 103 patients were included for analysis. At one-year follow-up, control of bleeding was successful in 91% (41/45), and control of refractory ascites in 80% (8/10). In patients with variceal bleeding, a higher MELD score was a risk factor for 90-day mortality (HR 1.28 per point, p < 0.001) and one-year mortality (HR 1.24 per point, p < 0.001). In patients with refractory ascites, a higher MELD score was only a risk factor for 90-day mortality (HR 1.13 per point, p = 0.03). Doppler ultrasound investigations during follow-up revealed abnormalities in 4% (6/166), all of which were associated with clinical deterioration, while abnormalities were detected in 11.4% (19/166) of patients who presented with clinical symptoms of TIPS dysfunction.

Conclusion: The use of routine Doppler ultrasound follow-up after PTFE-covered TIPS placement seems unnecessary as it had a very low yield and abnormal Doppler findings were almost always associated with clinical symptoms of TIPS dysfunction.

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来源期刊
Netherlands Journal of Medicine
Netherlands Journal of Medicine 医学-医学:内科
自引率
0.00%
发文量
0
审稿时长
6-12 weeks
期刊介绍: The Netherlands Journal of Medicine publishes papers in all relevant fields of internal medicine. In addition to reports of original clinical and experimental studies, reviews on topics of interest or importance, case reports, book reviews and letters to the editor are welcomed.
期刊最新文献
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