人体磁共振扫描仪在7T的安全性。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2022-10-01 Epub Date: 2021-08-06 DOI:10.2463/mrms.rev.2021-0063
Tomohisa Okada, Thai Akasaka, Dinh Hd Thuy, Tadashi Isa
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引用次数: 1

摘要

自1999年推出第一台人体7特斯拉(7T)系统以来,7T磁共振系统已被用作人体磁共振研究的最先进平台之一,已有20多年的历史。目前,有两种7T MR模型在美国被批准用于临床应用,批准促进了7T系统的引入,全球总计约100种。日本的批准等待已久。作为一种临床核磁共振扫描仪,7T核磁共振系统在安全性方面受到关注。一些关于眩晕、头晕、运动障碍、恶心等生物效应的大型研究已被报道。这种影响也可能在磁共振工作者和研究人员身上发现。报告的生物效应的频率和严重程度将被介绍和讨论,包括它们的差异。7T的高谐振频率和较短的射频波长增加了人们对其安全性的关注。均匀的射频脉冲激发即使对大脑也是困难的,多通道并行传输(pTx)系统被认为是强制性的。然而,pTx可能会产生一个热点,这使得比吸收率(SAR)的估计变得困难。7T磁场较强,对金属植入物或装置产生较大的位移力和发热力,不宜在7T下对患者进行扫描。然而,也有一些观点认为,即使在7T,如果满足某些标准,也可以对此类患者进行扫描。本文简要综述了静磁场对人类(磁共振受试者、工作人员和研究人员)和神经元的影响,以及扫描声音、SAR和金属植入物和设备的影响。了解和避免不良影响将有助于减少安全风险和预防事故。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Safety for Human MR Scanners at 7T.

After introduction of the first human 7 tesla (7T) system in 1999, 7T MR systems have been employed as one of the most advanced platforms for human MR research for more than 20 years. Currently, two 7T MR models are approved for clinical use in the U.S.A. The approval facilitated introduction of the 7T system, summing up to around 100 worldwide. The approval in Japan is much awaited. As a clinical MR scanner, the 7T MR system is drawing attention in terms of safety.Several large-sized studies on bioeffects have been reported for vertigo, dizziness, motion disturbances, nausea, and others. Such effects might also be found in MR workers and researchers. Frequency and severity of reported bioeffects will be presented and discussed, including their variances. The high resonance frequency and shorter RF wavelength of 7T increase the concern about the safety. Homogeneous RF pulse excitation is difficult even for the brain, and a multi-channel parallel transmit (pTx) system is considered mandatory. However, pTx may create a hot spot, which makes the estimation of specific absorption rate (SAR) to be difficult. The stronger magnetic field of 7T causes a large force of displacement and heating on metallic implants or devices, and the scan of patients with them should not be conducted at 7T. However, there are some opinions that such patients might be scanned even at 7T, if certain criteria are met. This article provides a brief review on the effect of the static magnetic field on humans (MR subjects, workers, and researchers) and neurons, in addition to scan sound, SAR, and metal implants and devices. Understanding and avoiding adverse effects will contribute to the reduction in safety risks and the prevention of incidents.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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