SIRS模型离散时间公式中的均匀混合和网络近似。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2021-12-01 DOI:10.1080/17513758.2021.2005835
Ilaria Renna
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引用次数: 1

摘要

提出了一种离散时间确定性流行病模型,以更好地理解传染病的传染动力学和在实际传染病发病率中观察到的行为。为此,我们在随机混合方法和小世界网络公式中分析了SIRS模型。这些模型包括表征流行病的基本参数:感染和恢复时间,以及传染机制。根据参数的不同,随机混合模型具有不同类型的流行病行为:病原体灭绝;流行感染;持续振荡和动态消光。空间效应包括在我们基于网络的方法中,其中人口的每个个体都由小世界网络的节点表示。我们基于网络的方法包括重新布线连接,以考虑时变的网络结构,这是对流行病出现的自然反应的结果(例如,避免与受感染的个体接触)。分析了随机和自适应重布线条件,并进行了数值模拟。将模型预测与意大利和法国发生的COVID-19感染对人口的实际影响进行了比较。感染者的时间序列结果表明,我们的自适应进化网络代表了能够减少流行病传播的有效策略。
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Homogenous mixing and network approximations in discrete-time formulation of a SIRS model.

A discrete-time deterministic epidemic model is proposed to better understand the contagious dynamics and the behaviour observed in the incidence of real infectious diseases. For this purpose, we analyse a SIRS model both in a random-mixing approach and in a small-world network formulation. The models include the basic parameters that characterize an epidemic: infection and recovery times, as well as mechanisms of contagion. Depending on the parameters, the random-mixing model has different types of behaviour of an epidemic: pathogen extinction; endemic infection; sustained oscillations and dynamic extinction. Spatial effects are included in our network-based approach, where each individual of a population is represented by a node of a small-world network. Our network-based approach includes rewiring connections to account for time-varying network structure, a consequence of the natural response to the emergence of an epidemic (e.g. avoiding contacts with infected individuals). Random and adaptive rewiring conditions are analysed and numerical simulation are made. A comparison of model predictions with the actual effects of COVID-19 infection on population that occurred in Italy and France is produced. Results of the time series of infected people show that our adaptive evolving networks represent effective strategies able to decrease the epidemic spreading.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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