会阴前列腺根治性切除术对远期勃起功能的影响

IF 0.8 4区 医学 Q4 ANDROLOGY Revista Internacional De Andrologia Pub Date : 2022-07-01 DOI:10.1016/j.androl.2020.12.007
Kafkasli Alper , Yazici Ozgur , Erbin Akif , Alkan Cubuk , Tuncer Murat , Canguven Onder , Akca Oktay , Albayrak Selami
{"title":"会阴前列腺根治性切除术对远期勃起功能的影响","authors":"Kafkasli Alper ,&nbsp;Yazici Ozgur ,&nbsp;Erbin Akif ,&nbsp;Alkan Cubuk ,&nbsp;Tuncer Murat ,&nbsp;Canguven Onder ,&nbsp;Akca Oktay ,&nbsp;Albayrak Selami","doi":"10.1016/j.androl.2020.12.007","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>Although many patients are being treated by radical prostatectomy (RP), there is still insufficient information about the changes in long-term erectile function after RP. Our aim is to examine long term, up to 5 year erectile function status of patients after Radical Perineal Prostatectomy (RPP).</p></div><div><h3>Materials and methods</h3><p>One hundred and thirty-two patients, who underwent bilateral nerve-sparing Radical Perineal Prostatectomy (RPP) in between January 2012 and January 2017, with preoperative age<!--> <!-->≤<!--> <!-->70, prostate volume<!--> <!-->&lt;<!--> <!-->80<!--> <!-->g, transrectal ultrasound (TRUS) guided biopsy Gleason score (GS)<!--> <!-->&lt;<!--> <!-->7, prostate specific antigen (PSA) value<!--> <!-->&lt;<!--> <!-->10<!--> <!-->ng/mL, and cT stage<!--> <!-->≤<!--> <!-->2 (N0, M0) were included into this study. Exclusion criteria were previous cardiovascular diseases, serious chronic renal and/or hepatic insufficiency, neurological diseases, uncontrolled diabetes mellitus, and severe lung diseases. Patients who received additional treatment (hormonal and/or radiotherapy) after RPP were also excluded from the study group. Erectile function was evaluated before surgery and at postoperative 3rd, 12th, and 60th months. Patients with an “International Index of Erectile Function (IIEF) – 5” score of ≥21 and patients whose IIEF-5 scores were between 16 and 20 but responded as “yes” to the “Sexual Encounter Profile (SEP) – 2” and “SEP-3” questions were accepted as having normal erectile function.</p></div><div><h3>Results</h3><p>Out of the 132 patients, 96 (72.7%) of the patients were found to be potent in the first postoperative year. A total of 118 patients were evaluated at the end of 5 years. Eighty seven (73.7%) patients had normal erectile function according to our criteria.</p></div><div><h3>Discussion</h3><p>According to the results of our study, short term and long term erectile function outcomes of patients undergoing RPP were favorable and there was no statistically significant difference between short and long term results.</p></div>","PeriodicalId":49129,"journal":{"name":"Revista Internacional De Andrologia","volume":null,"pages":null},"PeriodicalIF":0.8000,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Long term erectile function results of radical perineal prostatectomy\",\"authors\":\"Kafkasli Alper ,&nbsp;Yazici Ozgur ,&nbsp;Erbin Akif ,&nbsp;Alkan Cubuk ,&nbsp;Tuncer Murat ,&nbsp;Canguven Onder ,&nbsp;Akca Oktay ,&nbsp;Albayrak Selami\",\"doi\":\"10.1016/j.androl.2020.12.007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><p>Although many patients are being treated by radical prostatectomy (RP), there is still insufficient information about the changes in long-term erectile function after RP. Our aim is to examine long term, up to 5 year erectile function status of patients after Radical Perineal Prostatectomy (RPP).</p></div><div><h3>Materials and methods</h3><p>One hundred and thirty-two patients, who underwent bilateral nerve-sparing Radical Perineal Prostatectomy (RPP) in between January 2012 and January 2017, with preoperative age<!--> <!-->≤<!--> <!-->70, prostate volume<!--> <!-->&lt;<!--> <!-->80<!--> <!-->g, transrectal ultrasound (TRUS) guided biopsy Gleason score (GS)<!--> <!-->&lt;<!--> <!-->7, prostate specific antigen (PSA) value<!--> <!-->&lt;<!--> <!-->10<!--> <!-->ng/mL, and cT stage<!--> <!-->≤<!--> <!-->2 (N0, M0) were included into this study. Exclusion criteria were previous cardiovascular diseases, serious chronic renal and/or hepatic insufficiency, neurological diseases, uncontrolled diabetes mellitus, and severe lung diseases. Patients who received additional treatment (hormonal and/or radiotherapy) after RPP were also excluded from the study group. Erectile function was evaluated before surgery and at postoperative 3rd, 12th, and 60th months. Patients with an “International Index of Erectile Function (IIEF) – 5” score of ≥21 and patients whose IIEF-5 scores were between 16 and 20 but responded as “yes” to the “Sexual Encounter Profile (SEP) – 2” and “SEP-3” questions were accepted as having normal erectile function.</p></div><div><h3>Results</h3><p>Out of the 132 patients, 96 (72.7%) of the patients were found to be potent in the first postoperative year. A total of 118 patients were evaluated at the end of 5 years. Eighty seven (73.7%) patients had normal erectile function according to our criteria.</p></div><div><h3>Discussion</h3><p>According to the results of our study, short term and long term erectile function outcomes of patients undergoing RPP were favorable and there was no statistically significant difference between short and long term results.</p></div>\",\"PeriodicalId\":49129,\"journal\":{\"name\":\"Revista Internacional De Andrologia\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2022-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Internacional De Andrologia\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1698031X2200019X\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"ANDROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Internacional De Andrologia","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1698031X2200019X","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ANDROLOGY","Score":null,"Total":0}
引用次数: 0

摘要

虽然许多患者正在接受根治性前列腺切除术(RP)治疗,但关于RP后长期勃起功能的变化的信息仍然不足。我们的目的是研究根治性会阴前列腺切除术(RPP)后患者长达5年的长期勃起功能状态。材料与方法2012年1月~ 2017年1月行双侧保留神经的会阴根治性前列腺切除术(RPP)患者132例,术前年龄≤70岁,前列腺体积<80 g,经直肠超声(TRUS)引导活检Gleason评分(GS) <7、前列腺特异性抗原(PSA)值<10 ng/mL, cT分期≤2 (N0, M0)纳入本研究。排除标准为既往心血管疾病、严重慢性肾功能和/或肝功能不全、神经系统疾病、未控制的糖尿病和严重肺部疾病。在RPP后接受额外治疗(激素和/或放疗)的患者也被排除在研究组之外。术前、术后第3、12、60个月评估勃起功能。“国际勃起功能指数(IIEF) -5”得分≥21,IIEF-5得分在16 - 20之间,但对“性接触概况(SEP) - 2”和“SEP-3”问题回答为“是”的患者被认为具有正常的勃起功能。结果132例患者中,96例(72.7%)患者在术后1年内出现有效。5年结束时共对118例患者进行评估。87例(73.7%)患者勃起功能正常。根据我们的研究结果,RPP患者的短期和长期勃起功能结局良好,短期和长期结果无统计学差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Long term erectile function results of radical perineal prostatectomy

Introduction

Although many patients are being treated by radical prostatectomy (RP), there is still insufficient information about the changes in long-term erectile function after RP. Our aim is to examine long term, up to 5 year erectile function status of patients after Radical Perineal Prostatectomy (RPP).

Materials and methods

One hundred and thirty-two patients, who underwent bilateral nerve-sparing Radical Perineal Prostatectomy (RPP) in between January 2012 and January 2017, with preoperative age  70, prostate volume < 80 g, transrectal ultrasound (TRUS) guided biopsy Gleason score (GS) < 7, prostate specific antigen (PSA) value < 10 ng/mL, and cT stage  2 (N0, M0) were included into this study. Exclusion criteria were previous cardiovascular diseases, serious chronic renal and/or hepatic insufficiency, neurological diseases, uncontrolled diabetes mellitus, and severe lung diseases. Patients who received additional treatment (hormonal and/or radiotherapy) after RPP were also excluded from the study group. Erectile function was evaluated before surgery and at postoperative 3rd, 12th, and 60th months. Patients with an “International Index of Erectile Function (IIEF) – 5” score of ≥21 and patients whose IIEF-5 scores were between 16 and 20 but responded as “yes” to the “Sexual Encounter Profile (SEP) – 2” and “SEP-3” questions were accepted as having normal erectile function.

Results

Out of the 132 patients, 96 (72.7%) of the patients were found to be potent in the first postoperative year. A total of 118 patients were evaluated at the end of 5 years. Eighty seven (73.7%) patients had normal erectile function according to our criteria.

Discussion

According to the results of our study, short term and long term erectile function outcomes of patients undergoing RPP were favorable and there was no statistically significant difference between short and long term results.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
1.60
自引率
12.50%
发文量
54
审稿时长
>12 weeks
期刊介绍: Revista Internacional de Andrología es la revista oficial de la Asociación Española de Andrología, Medicina Sexual y Reproductiva (ASESA), la Sociedade Portuguesa de Ardrologia, la Sociedad Argentina de Andrología (SAA), la Asociación Iberoamericana de Sociedades de Andrología (ANDRO), y la Federación Española de Sociedades de Sexología. La revista publicada trimestralmente es revisada por pares y es líder en el la especialidad y en español y portugués. Recientemente también publica artículos en inglés. El objetivo de la revista es principalmente la promoción del conocimiento y la educación médica continua, con un enfoque especial en el público español y latinoamericano, a través de la publicación de las contribuciones importantes de la investigación en el campo. Todos los miembros de las sociedades antes mencionadas reciben la revista y otros suscriptores individuales e institucionales de España, Portugal y América Latina.
期刊最新文献
A possible mechanism of erectile dysfunction in coronavirus disease-19: Cavernosal smooth muscle damage: A pilot study Therapeutic effects of melatonin in long-term exposure to 2100 MHz radiofrequency radiation on rat sperm characteristics Exploring the anatomical factors influencing testes elasticity via ultrasound shear wave elastography: Preliminary results Resveratrol ameliorates spermatogenesis by increasing protamine 1, 2 and HSPA2 expression in experimental varicocele rat model Effect of icariin on the transformation efficiency of induced pluripotent stem cells into sperm cells in vitro
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1