无尿肾衰竭与锌中毒的狗。

Veterinary and human toxicology Pub Date : 2004-10-01
Petra A Volmer, Jennifer Roberts, Gavin L Meerdink
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引用次数: 0

摘要

无尿肾衰竭的发展与锌中毒是检测在狗摄取装饰性黄铜旋钮从厕纸架。这只3岁,雄性绝育,15.4公斤的威尔士柯基犬被送到当地兽医诊所,有2个月的间歇性呕吐,食欲不振和嗜睡的历史。这只狗被转移到兽医教学医院,在那里进行手术切除异物。由于无尿肾衰竭的发展,狗在术后24小时被安乐死。手术时全血血清锌浓度为89.8 ppm(正常为0.7-2.0 ppm)。这只狗的血清锌浓度是文献中报道的最高浓度。摄入任何含锌的金属物体都可能导致严重的血管内溶血,并导致肾功能损害。当溶血并在肠道内发现金属物体时,应怀疑锌中毒。
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Anuric renal failure associated with zinc toxicosis in a dog.

The development of anuric renal failure associated with zinc intoxication was detected in a dog following ingestion of an ornamental brass knob from a toilet paper holder. The 3-y-old, male neutered, 15.4 kg Welsh Corgi presented to a local veterinary clinic with a 2-w history of intermittent vomiting, inappetance and lethargy. The dog was transferred to a veterinary teaching hospital where surgery was performed to remove the foreign body. The dogwas euthanized 24 h post-surgery due to the development of anuric renal failure. Whole blood drawn at the time of surgery had a serum zinc concentration of 89.8 ppm (normal 0.7-2.0 ppm). The serum zinc concentration in this dog is the highest reported concentration in the literature. Ingestion of any zinc-containing metal object can potentially result in a severe intravascular hemolysis with subsequent renal impairment. Zinc intoxication should be suspected when hemolysis is accompanied by the finding of a metallic object in the gut.

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