{"title":"从老花Gypsophila oldhamiana花中分离得到一对非对映异构体C-呋喃葡萄糖基黄酮。","authors":"Hai-Yan Wu, Hong-Min Xia, Wan-Jin Zheng","doi":"10.1080/14786419.2023.2261138","DOIUrl":null,"url":null,"abstract":"<p><p>Two new <i>C</i>-glucofuranosyl flavones apigenin 6-C-<i>β</i>-glucofuranoside (<b>1</b>) and apigenin 6-C-<i>α</i>-glucofuranoside (<b>2</b>) together with four known compounds (<b>3</b>-<b>6</b>) were isolated from the flowers of <i>Gypsophila oldhamiana.</i> Their structures were elucidated on the basis of extensive spectroscopic analyses. These compounds were evaluated for the cytotoxic activities against four human cancer cell lines and did not exhibit any significant bioactivities (IC<sub>50</sub> values > 10 <i>μ</i>M).</p>","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"248-252"},"PeriodicalIF":1.9000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A pair of diastereoisomeric <i>C</i>-glucofuranosyl flavones from the flowers of <i>Gypsophila oldhamiana</i>.\",\"authors\":\"Hai-Yan Wu, Hong-Min Xia, Wan-Jin Zheng\",\"doi\":\"10.1080/14786419.2023.2261138\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Two new <i>C</i>-glucofuranosyl flavones apigenin 6-C-<i>β</i>-glucofuranoside (<b>1</b>) and apigenin 6-C-<i>α</i>-glucofuranoside (<b>2</b>) together with four known compounds (<b>3</b>-<b>6</b>) were isolated from the flowers of <i>Gypsophila oldhamiana.</i> Their structures were elucidated on the basis of extensive spectroscopic analyses. These compounds were evaluated for the cytotoxic activities against four human cancer cell lines and did not exhibit any significant bioactivities (IC<sub>50</sub> values > 10 <i>μ</i>M).</p>\",\"PeriodicalId\":18990,\"journal\":{\"name\":\"Natural Product Research\",\"volume\":\" \",\"pages\":\"248-252\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Natural Product Research\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1080/14786419.2023.2261138\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/9/26 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Natural Product Research","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1080/14786419.2023.2261138","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/9/26 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
A pair of diastereoisomeric C-glucofuranosyl flavones from the flowers of Gypsophila oldhamiana.
Two new C-glucofuranosyl flavones apigenin 6-C-β-glucofuranoside (1) and apigenin 6-C-α-glucofuranoside (2) together with four known compounds (3-6) were isolated from the flowers of Gypsophila oldhamiana. Their structures were elucidated on the basis of extensive spectroscopic analyses. These compounds were evaluated for the cytotoxic activities against four human cancer cell lines and did not exhibit any significant bioactivities (IC50 values > 10 μM).
期刊介绍：
The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds.
The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal.
Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section.
All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.
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