生物医学应用的金属有机框架生物材料

IF 1.6 Q4 ENGINEERING, BIOMEDICAL Biosurface and Biotribology Pub Date : 2021-06-08 DOI:10.1049/bsb2.12012
Gang Luo, Yanan Jiang, Chaoming Xie, Xiong Lu
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引用次数: 4

摘要

金属有机骨架是指由金属离子与有机配体组装而成的多孔配位材料。它们具有独特的特性,如大的比表面积,多个活性位点,易于功能化和可调节的生物相容性。mof以其独特的结构和性能在生物医学工程领域得到了广泛的应用。这使它们能够取代传统材料,并有效地解决几个问题。经过不断的发展,MOF基生物材料的结构与性能之间的关系逐渐明晰,得到了显著的改善。因此,它们正在化学和材料科学领域得到广泛研究。mof基生物材料可以满足生物医学领域对高效材料日益增长的需求。本文首先介绍了MOFs的基本结构、制备方法和功能化方法。然后总结了mof基生物材料在抗菌活性、肿瘤治疗、皮肤修复和骨修复等领域的生物医学应用。最后,概述了mof基生物材料在生物医学应用中的挑战和未来前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Metal-organic framework-based biomaterials for biomedical applications

Metal-organic frameworks (MOFs) refer to porous coordination materials that are formed from the assembly of metal ions and organic ligands. They have unique features, such as a large specific surface area, multiple active sites, easy functionalisation, and adjustable biocompatibility. MOFs have recently been widely used in the field of biomedical engineering owing to their unique structures and properties. This has enabled them to replace traditional materials and effectively address several problems. Through continuous development, MOF-based biomaterials have been remarkably improved by clarifying the relationship between MOF structures and properties. As a result, they are being extensively studied in the fields of chemical and material science. MOF-based biomaterials can meet the growing demands for efficient materials in biomedical applications. This review first discusses the basic structure of MOFs, followed by their preparation and functionalisation methods. The biomedical applications of MOF-based biomaterials in the fields of antibacterial activity, tumour therapy, skin repair, and bone repair are then summarised. Finally, challenges and future perspectives in the biomedical applications of MOF-based biomaterials are outlined.

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来源期刊
Biosurface and Biotribology
Biosurface and Biotribology Engineering-Mechanical Engineering
CiteScore
1.70
自引率
0.00%
发文量
27
审稿时长
11 weeks
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