药用植物抗阿尔茨海默病的潜在作用

S. Yadav
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引用次数: 2

摘要

阿尔茨海默病(AD)是一种进行性大脑神经退行性疾病,会导致记忆力和认知能力下降。美国食品和药物管理局(FDA)批准的药物只提供症状缓解,往往与不良反应有关。许多天然产物已显示出抗AD的活性。生物活性化合物如多酚、单宁、生物碱、类黄酮、萜烯、甾醇等存在于各种植物中。这些化合物具有抗氧化、抗炎、抗胆碱酯酶和抗淀粉样变性活性。本文就各种植物抗AD的作用作一综述。
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Potential role of medicinal plants against Alzheimer’s disease
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder of the brain which leads to a decline in memory and cognition. The Food and Drug Administration (FDA) approved medications provide only symptomatic relief and are often associated with adverse effects. Many natural products have shown their activities against AD. Bioactive compounds like polyphenols, tannins, alkaloids, flavonoids, terpenes, sterols, etc are present in various plants. These compounds have shown antioxidant, anti-inflammatory, anticholinesterase, and anti-amyloidogenic activities. This review article discusses the benefits of various plants against AD.
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