儿童特应性皮炎:最新的治疗方案

C. Zah, Andreea Emiliana Toporău, Paul Grama
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引用次数: 1

摘要

摘要特应性皮炎(AD)是一种以皮肤干燥、瘙痒和湿疹样病变为特征的慢性炎症性疾病,并伴有不同时期的复发。症状可能出现在儿童时期,并可能持续到成年。慢性治疗需要皮质类固醇作为标准选择。这种类型的长期治疗的副作用代表了儿科患者的主要担忧。本综述旨在更新除全身皮质类固醇外的治疗方案。轻度至中度AD对含有无花果和燕麦提取物以及磷酸二酯酶-4抑制剂(crisaborole)的乳膏有良好的反应。在严重AD的病例中,未来的治疗选择可能包括单克隆抗体,如奥马珠单抗和杜匹单抗
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Pediatric Atopic Dermatitis: Update on the Treatment Options
Abstract Atopic dermatitis (AD) is a chronic inflammatory disease characterized by skin dryness, pruritus and eczematous lesions with various periods of relapse. Symptomatology can appear in childhood and can persist in adulthood. Chronic treatment is required with corticosteroids being the standard options. The side effects of this type of long-term treatment represent a major concern for the pediatric patients. This review aims to give an update of the options used for treatment, apart from the systemic corticosteroids. Mild-to-moderate AD had a good response to creams containing fig and oatmeal extracts and inhibitors of phosphodiesterase-4 (crisaborole). In cases of severe AD, future treatment options could include monoclonal antibodies such as omalizumab and dupilumab
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