黄连根及其地上部分提取物的生物活性及化学成分研究。

IF 0.5 4区生物学 Q4 PLANT SCIENCES Acta Biologica Colombiana Pub Date : 2022-03-31 DOI:10.15446/abc.v27n3.95476

Fatima Zohra Houari, R. Erenler, A. Hariri

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引用次数: 4

摘要

本研究主要研究了红檗根部和地上部氢甲醇提取物的植物化学成分、抗氧化和抗溶血活性。植物化学筛选揭示了酚、生物碱、香豆素、黄酮类化合物和单宁在两种提取物中的存在。LC-ESI-MS/MS分析显示，根和地上部位提取物中分别含有15种和17种成分。定量分析表明，黄酮类化合物(45.29±0.04 mg GAE/g)和酚类化合物(118.38 mg GAE/g)含量最高，单宁含量(134.1±0.1 mg GAE/g)最高。此外，地皮部位提取物对DPPH(83.23%)和FRAP(1.51±0.22)的抗氧化活性最高，而根部位提取物对TAC和抗溶血活性的抗氧化活性最高(61.09%)。黑檀香含有不同的活性化合物，可以预防与氧化应激有关的疾病。

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BIOLOGICAL ACTIVITIES AND CHEMICAL COMPOSITION OF Rubia tinctorum (L) ROOT AND AERIAL PART EXTRACTS THEREOF.

In the present study, the phytochemical composition, antioxidant and anti-hemolytic activities of root and aerial part Rubia tinctorum hydromethanolic extracts were investigated. Phytochemical screening reveals the presence of phenol, alkaloids, coumarin, flavonoids, and tannins in both extracts. LC-ESI-MS/MS analysis showed the presence of 15 and 17 components in the root and the aerial part extracts, respectively. The quantitative analysis indicates the richness of root extracts in phenolic compounds (118.38 mg GAE/g) and flavonoids (45.29±0.04 mg GAE/g), the aerial part extract has the highest levels in tannins (134.1±0.1 mg GAE/g). Besides, aerial part extracts revealed the highest antioxidant activity for DPPH (83.23 %) and FRAP (1.51±0.22), while the root extract exhibited the highest potential for TAC and antihemolytic activity (61.09 %). Rubia tinctorum contains different active compounds to prevent diseases related to oxidative stress.

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来源期刊

Acta Biologica Colombiana Agricultural and Biological Sciences-General Agricultural and Biological Sciences

CiteScore

1.60

自引率

0.00%

发文量

审稿时长

13 weeks

期刊介绍： The journal is published quarterly and divulges original and unpublished results of basic and applied research about biological subjects with special interest in Neotropical region. Manuscripts may be research articles, reviews, reflection articles or short notes. The Acta biol. Colomb Journal have a scientific and editorial board composed of expert researchers of in their areas of knowledge.