慢性肺部疾病的肺部康复。

Ledi Neçaj
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摘要

慢性阻塞性肺病(COPD)是目前发达国家致残的主要原因。COPD的进展与呼吸困难、残疾和周期性住院的增加有关。发达国家的人口老龄化和发展中国家日益增长的香烟消费扩大了这种情况的全球影响。与COPD相关的疾病会导致体力活动减少和功能独立性失败。本研究的目的是评估PR在运动能力正常的患者中对健康相关的生活质量和运动能力的影响。平均FEV1/FVC为59.4±14.1%,平均FEV1为64.8±23.0%。大多数受试者患有轻度至中度COPD。PImax和PEmax正常。这些受试者以前没有参加过家庭或医院的PR。所有受试者在PR前的最大V*O2和工作率都正常。PR后的最大V*O2(平均增加101.3 mL/min,p<0.001)和工作率(平均增加8.2瓦特,<0.001)仍有相当大的改善。PR后通气、心率和平均血压保持不变。最大运动量时的最大氧脉冲随PR而显著增加(p<0.02)。PR后运动高峰时的SpO2和潮末PCO2没有显著改善。尽管休息时的呼吸困难评分较低,PR后也没有显著改善,PR后运动末期呼吸困难明显改善(p=0.01)。COPD患者的临床管理应负责PR,即使是那些运动能力正常的患者。然而,这些患者的疾病进展、住院治疗和生存率的益处仍然未知。在包括肺病在内的任何慢性疾病的管理中,主要作用是提高患者的生活质量。结论尽管科学学会强烈建议,但肺部康复计划仍需更广泛地实施。PR项目已经显示出对慢性呼吸系统患者,特别是COPD患者有益的高水平证据。
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Pulmonary Rehabilitation for Chronic Lung Diseases.
Chronic Obstructive Pulmonary Disease (COPD) is now the main cause of disability in the developed world. The advance of COPD is related to increasing breathlessness, disability, and periodic hospitalizations.  An aging population in the developed world and increasing cigarette consumption in developing countries expand the global impact of this condition. The disorder associated with COPD leads to a decrease in physical activity and failure of functional independence. The aim of this study was to evaluate the effects of PR in patients with normal exercise capacity on health-related quality of life and exercise capacity. The mean FEV1/FVC was 59.4± 14.1%, and the mean FEV1 was 64.8± 23.0% as expected. Most topics had mild to moderate COPD. The PImax and PEmax were normal. These subjects had no previous participation in home-based or hospital-based PR. All the subjects had normal maximal V˙O2 and work rate before PR. After PR there were still considerable improvements in maximal V˙O2 (mean increase of 101.3 mL/min, p <0.001) and work rate (mean increase of 8.2 watts, p<0.001). Ventilation, heart rate, and mean blood pressure were constant following PR. The maximum oxygen pulse at maximum exercise was significantly increased with PR (p<0.02). The SpO2 and end-tidal PCO2 at peak exercise did not significantly improve after PR.  Although dyspnea scores at rest were low and did not improve significantly with PR, dyspnea at end-exercise was significantly improved after PR (p=0.01). PR should be the responsibility of the clinical management of patients with COPD, even for those with normal exercise capacity. However, the benefits of disease progression, hospitalization, and survival for these patients remain unknown. The main role in the management of any chronic disease, including lung disease, is to improve the quality of life (QL) in patients. Conclusion; Although strongly recommended by scientific societies pulmonary rehabilitation programs still need to be more widely implemented. PR programs have shown a high level of evidence of benefits in chronic respiratory patients, particularly those with COPD.
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