使用压缩和增强CNN的新频道的疟疾寄生虫分类框架。

IF 1.5 4区 工程技术 Q3 MICROSCOPY Microscopy Pub Date : 2022-05-30 DOI:10.1093/jmicro/dfac027
Dr. Saddam Hussain Khan, Najmus Saher Shah, Rabia Nuzhat, A. Majid, Hani Alquhayz, Asifullah Khan
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引用次数: 15

摘要

疟疾是一种危及生命的感染,它会感染逐渐在全身生长的红细胞。疟原虫是由雌性按蚊叮咬引起的,每年都会严重影响世界上许多人。因此,需要进行早期检测测试来预测感染的寄生细胞。所提出的技术利用深度卷积神经网络(CNN)学习能力从健康个体中检测薄血涂片寄生虫患者。在这方面,检测是使用一种新的基于STM SB RENet块的CNN来完成的,该CNN以改进的方式采用了分割变换合并(STM)和信道压缩增强(SB)的思想。在这方面,开发了一种新的基于卷积块的STM,它系统地实现了区域和边缘运算,以探索与区域同质性、结构阻塞和边界定义特征相关的寄生疟疾模式。此外,通过在抽象、中间和目标级别将新的通道SB和转移学习(TL)思想结合到每个STM块中,以捕捉寄生和正常伪影之间的微小对比度和纹理变化,实现了不同的增强特征图。最初使用离散小波变换对所提出的模型的疟疾输入图像进行变换,以生成增强和缩小的特征空间。在国家卫生疟疾研究所数据集上使用保持交叉验证对所提出的架构进行了验证。所提出的方法优于从头开始的训练,以及基于TL的微调现有技术。STM-SB-RENet的显著性能(准确度:97.98%,灵敏度:0.988,F-评分:0.980,AUC:0.996)表明它可以用于筛查寄生虫疟疾患者。
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Malaria Parasite Classification Framework using a Novel Channel Squeezed and Boosted CNN.
Malaria is a life-threatening infection that infects the red blood cells (RBCs) that gradually grows throughout the body. The plasmodium parasite is caused by a female anopheles mosquito bite and severely affects numerous individuals within the world every year. Therefore, early detection tests are required to predict infected parasitic cells. The proposed technique exploits deep convolutional neural network (CNN) learning capability to detect the thin-blood smear parasitic patients from healthy individuals. In this regard, the detection is accomplished using a novel STM-SB-RENet block-based CNN that employs the idea of split-transform-merge (STM) and channel Squeezing-Boosting (SB) in a modified fashion. In this connection, a new convolutional block-based STM is developed, which systematically implements region and edge operations to explore the parasitic malaria pattern related to region-homogeneity, structural obstruction, and boundary-defining features. Moreover, the diverse boosted feature maps are achieved by incorporating the new channel SB and Transfer Learning (TL) idea in each STM block at abstract, intermediate, and target levels to capture minor contrast and texture variation between parasitic and normal artifacts. The malaria input images to the proposed models are initially transformed using discrete wavelet transform to generate enhanced and reduced feature space. The proposed architectures are validated using hold-out cross-validation on the National Institute of Health Malaria dataset. The proposed methods outperform the train from scratch, and TL-based fine-tuned existing techniques. The considerable performance (accuracy: 97.98%, sensitivity: 0.988, F-score: 0.980, and AUC: 0.996) of STM-SB-RENet suggests that it can be utilized to screen parasitic malaria patients.
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来源期刊
Microscopy
Microscopy Physics and Astronomy-Instrumentation
CiteScore
3.30
自引率
11.10%
发文量
76
期刊介绍: Microscopy, previously Journal of Electron Microscopy, promotes research combined with any type of microscopy techniques, applied in life and material sciences. Microscopy is the official journal of the Japanese Society of Microscopy.
期刊最新文献
In This Issue Real-time scanning electron microscopy of unfixed tissue in the solution using a deformable and electron-transmissive film Atomic-Resolution STEM Image Denoising by Total Variation Regularization. Super-Resolution Reconstruction Based on BM3D and Compressed Sensing. Reliable Electrochemical Setup for in situ Observations with an Atmospheric SEM.
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