氧化锌纳米颗粒对食源性病原菌大肠杆菌和金黄色葡萄球菌的抑制作用

IF 0.4 Q4 CHEMISTRY, MULTIDISCIPLINARY Jordan Journal of Chemistry Pub Date : 2020-08-26 DOI:10.47014/15.2.4
Khaled Saif Aldin, S. Al-Hariri, Adnan Ali-Nizam
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引用次数: 2

摘要

本文研究了用共沉淀法制备的不同浓度的ZnO纳米颗粒(粒径范围为47 ~ 68 nm)作为抗菌药物。按照临床与实验室标准协会CLSI-2015-M07-A10推荐的标准方法,对革兰氏阳性金黄色葡萄球菌和革兰氏阴性大肠杆菌两种微生物进行稀释药敏试验。结果表明,溶液中ZnO纳米颗粒浓度越高,抑菌效果越明显。同时发现革兰氏阳性菌对ZnO纳米粒子的敏感性高于革兰氏阴性菌。对大肠杆菌最低抑菌浓度为50 mg/mL,对金黄色葡萄球菌最低抑菌浓度为25 mg/mL。最低杀菌浓度(MBC)对大肠杆菌为1600 mg/mL,对金黄色葡萄球菌为800 mg/mL。
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Effectiveness of ZnO Nano Particles against the Foodborne Microbial Pathogens E. coli and S. aureus
In this work, various concentrations of ZnO nano particles, prepared by the coprecipitation method with a size range of 47-68 nm, have been investigated as antimicrobial agents. Dilution antimicrobial susceptibility tests were carried out on two kinds of microbes (Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli) according to the standard method recommended by Clinical and Laboratory Standards Institute, CLSI-2015-M07-A10. The results showed that the antimicrobial effect is larger, the higher the concentration of ZnO nano particles in solution. It was also found that Gram-positive microbes are more sensitive to ZnO nano particles when compared with the Gram-negative ones. The minimum inhibitory concentration (MIC) for E. coli was found to be 50 mg/mL while that for S. aureus was 25 mg/mL. The minimum bactericidal concentration (MBC) was 1600 mg/mL for E. coli and 800 mg/mL for S. aureus.
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来源期刊
Jordan Journal of Chemistry
Jordan Journal of Chemistry CHEMISTRY, MULTIDISCIPLINARY-
CiteScore
0.50
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0.00%
发文量
7
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