胸腔镜支气管袖状肺叶切除术治疗中枢性非小细胞肺癌的疗效和安全性

Shuangping Zhang, Shi-ping Guo, Jianhong Lian, Yong Ma
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摘要

目的探讨胸腔镜支气管套筒肺叶切除术治疗中枢性非小细胞肺癌(NSCLC)的疗效,并评价其安全性。方法回顾性分析2015年5月至2018年9月山西省肿瘤医院胸腔镜支气管袖叶切除术29例患者的临床资料,分析手术效果及安全性。结果29例患者行胸腔镜支气管套筒肺叶切除术。其中右上袖叶切除13例,左上袖叶切除10例,左下袖叶切除6例。手术时间180 ~ 400 min,中位时间240 min。支气管吻合时间35 ~ 60 min,中位时间48 min。术中出血量150 ~ 460 ml,中位出血量220 ml。淋巴结清扫数12 ~ 39个/例,中位19.6个/例。术后放置胸腔引流管4 ~ 16天,中位时间6天;术后住院6 ~ 16天,中位9天。术后并发症发生率为24.1%(7/29),其中肺漏气1例(7/ 7天),肺部感染2例,心律失常3例,1例术后第7天出院,第40天因吻合口瘘出血死亡。其余患者术后恢复顺利。中位随访时间为6个月(3-12个月)。无肿瘤复发及吻合口狭窄。结论胸腔镜支气管套筒肺叶切除术是一种安全可行的治疗中枢性非小细胞肺癌的手术方法。关键词:肺癌,非小细胞肺;胸腔镜;袖叶切除术
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Efficacy and safety of thoracoscopic bronchial sleeve lobectomy for central non-small cell lung cancer
Objective To explore the efficacy of thoracoscopic bronchial sleeve lobectomy for central non-small cell lung cancer (NSCLC), and to evaluate the safety of this operation. Methods The clinical data of 29 patients who underwent thoracoscopic bronchial sleeve lobectomy at Shanxi Provincial Cancer Hospital from May 2015 to September 2018 were retrospectively analyzed, and the surgical effect and safety were analyzed. Results Twenty-nine cases underwent thoracoscopic bronchial sleeve lobectomy. The types of resection included 13 cases of right upper, 10 cases of left upper, and 6 cases of left lower sleeve lobectomy. The operation time was 180-400 min, and the median time was 240 min. The bronchial anastomosis time was 35-60 min, and the median time was 48 min. The intraoperative blood loss was 150-460 ml, and the median blood loss was 220 ml. The number of lymph node dissection was 12-39 lymph nodes per patient, with a median of 19.6 lymph nodes per patient. The thoracic drainage tube was placed for 4-16 days after operation, with a median of 6 days; the postoperative hospital stay was 6-16 days, with a median of 9 days. The postoperative complication rate was 24.1% (7/29), including 1 case with pulmonary air leakage (> 7 days), 2 cases with pulmonary infections, 3 cases with arrhythmia, and 1 patient discharged from the hospital on the 7th day after surgery, but died of anastomotic fistula bleeding on the 40th day. The rest of the patients recovered smoothly after surgery. The median follow-up time was 6 months (3-12 months). No tumor recurrence or anastomotic stenosis was observed. Conclusion Thoracoscopic bronchial sleeve lobectomy is a safe and feasible surgical treatment for central NSCLC. Key words: Carcinoma, non-small-cell lung; Thoracoscopes; Sleeve lobectomy
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肿瘤研究与临床
肿瘤研究与临床 Medicine-Oncology
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