{"title":"利用logistic回归分析估计奶牛乳腺炎与CXCR1基因生产性状相关的显性效应","authors":"Masoumeh Bagheri, Azadeh Zahmatkesh","doi":"10.1016/j.aggene.2016.11.006","DOIUrl":null,"url":null,"abstract":"<div><p><span>The dominance effect is important for mastitis, which is the major source of economic loss in dairy herds. The objective of this study was to evaluate dominance effects of </span><em>CXCR1</em><span> gene for clinical mastitis and production traits in Holstein dairy cattle using the selective genotyping method. Records of 305-day lactation were obtained for production traits and for the number of cases of clinical mastitis per lactation. Cows were selected based on extreme values (highest and lowest CMR values) for clinical mastitis residuals (CMR) from mixed model analyses. Each of the two extreme groups of cowswas genotyped for </span><em>CXCR1</em><span> gene and then, associations between genotypes and CMR and also breeding values for traits of interest were estimated by applying logistic regression analyses. Allele G of </span><em>CXCR1</em><span> gene was associated with fewer cases for clinical mastitis (CM), and showed desired effects on production traits, especially on milk, protein and fat yield. Effects of dominance ranged from −</span> <!-->0.03 SD to 0.55 SD for the production traits and CM. For milk production traits, positive values for dominance indicated a surplus in these traits. Result showed that <em>CXCR1</em> gene may be a valuable candidate gene for improvement of mastitis resistance as well as production traits in dairy cattle herds and the dominance effects may not be negligible.</p></div>","PeriodicalId":37751,"journal":{"name":"Agri Gene","volume":"3 ","pages":"Pages 63-66"},"PeriodicalIF":0.0000,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.aggene.2016.11.006","citationCount":"3","resultStr":"{\"title\":\"Estimation of dominance effects related to mastitis and production traits for CXCR1 gene using logistic regression analysis in dairy cattle\",\"authors\":\"Masoumeh Bagheri, Azadeh Zahmatkesh\",\"doi\":\"10.1016/j.aggene.2016.11.006\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><span>The dominance effect is important for mastitis, which is the major source of economic loss in dairy herds. The objective of this study was to evaluate dominance effects of </span><em>CXCR1</em><span> gene for clinical mastitis and production traits in Holstein dairy cattle using the selective genotyping method. Records of 305-day lactation were obtained for production traits and for the number of cases of clinical mastitis per lactation. Cows were selected based on extreme values (highest and lowest CMR values) for clinical mastitis residuals (CMR) from mixed model analyses. Each of the two extreme groups of cowswas genotyped for </span><em>CXCR1</em><span> gene and then, associations between genotypes and CMR and also breeding values for traits of interest were estimated by applying logistic regression analyses. Allele G of </span><em>CXCR1</em><span> gene was associated with fewer cases for clinical mastitis (CM), and showed desired effects on production traits, especially on milk, protein and fat yield. Effects of dominance ranged from −</span> <!-->0.03 SD to 0.55 SD for the production traits and CM. For milk production traits, positive values for dominance indicated a surplus in these traits. Result showed that <em>CXCR1</em> gene may be a valuable candidate gene for improvement of mastitis resistance as well as production traits in dairy cattle herds and the dominance effects may not be negligible.</p></div>\",\"PeriodicalId\":37751,\"journal\":{\"name\":\"Agri Gene\",\"volume\":\"3 \",\"pages\":\"Pages 63-66\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.aggene.2016.11.006\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Agri Gene\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2352215116300502\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Agricultural and Biological Sciences\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Agri Gene","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2352215116300502","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Agricultural and Biological Sciences","Score":null,"Total":0}
Estimation of dominance effects related to mastitis and production traits for CXCR1 gene using logistic regression analysis in dairy cattle
The dominance effect is important for mastitis, which is the major source of economic loss in dairy herds. The objective of this study was to evaluate dominance effects of CXCR1 gene for clinical mastitis and production traits in Holstein dairy cattle using the selective genotyping method. Records of 305-day lactation were obtained for production traits and for the number of cases of clinical mastitis per lactation. Cows were selected based on extreme values (highest and lowest CMR values) for clinical mastitis residuals (CMR) from mixed model analyses. Each of the two extreme groups of cowswas genotyped for CXCR1 gene and then, associations between genotypes and CMR and also breeding values for traits of interest were estimated by applying logistic regression analyses. Allele G of CXCR1 gene was associated with fewer cases for clinical mastitis (CM), and showed desired effects on production traits, especially on milk, protein and fat yield. Effects of dominance ranged from − 0.03 SD to 0.55 SD for the production traits and CM. For milk production traits, positive values for dominance indicated a surplus in these traits. Result showed that CXCR1 gene may be a valuable candidate gene for improvement of mastitis resistance as well as production traits in dairy cattle herds and the dominance effects may not be negligible.
Agri GeneAgricultural and Biological Sciences-Agricultural and Biological Sciences (miscellaneous)
自引率
0.00%
发文量
0
期刊介绍：
Agri Gene publishes papers that focus on the regulation, expression, function and evolution of genes in crop plants, farm animals, and agriculturally important insects and microorganisms. Agri Gene strives to be a diverse journal and topics in multiple fields will be considered for publication so long as their main focus is on agriculturally important organisms (plants, animals, insects, or microorganisms). Although not limited to the following, some examples of potential topics include: Gene discovery and characterization. Genetic markers to guide traditional breeding. Genetic effects of transposable elements. Evolutionary genetics, molecular evolution, population genetics, and phylogenetics. Profiling of gene expression and genetic variation. Biotechnology and crop or livestock improvement. Genetic improvement of biological control microorganisms. Genetic control of secondary metabolic pathways and metabolic enzymes of crop pathogens. Transcription analysis of beneficial or pest insect developmental stages Agri Gene encourages submission of novel manuscripts that present a reasonable level of analysis, functional relevance and/or mechanistic insight. Agri Gene also welcomes papers that have predominantly a descriptive component but improve the essential basis of knowledge for subsequent functional studies, or which provide important confirmation of recently published discoveries provided that the information is new.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
