蜂蜜作为绿色封端剂和还原剂生物合成Srco3纳米结构:光动力疗法

IF 1.4 Q4 NANOSCIENCE & NANOTECHNOLOGY Nanomedicine Journal Pub Date : 2019-04-01 DOI:10.22038/NMJ.2019.06.0003
M. Rezaeizadeh, M. Ranjbar, A. Pardakhty
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引用次数: 0

摘要

目的:SrCO3纳米颗粒可作为新的生物医学磁共振成像源,作为一种很有前途的无创成像方式,用于癌症术前分期和监测肿瘤对治疗的反应。本研究旨在利用微波辐射在蜂蜜作为绿色封端剂和还原剂的存在下合成SrCO3纳米结构。材料与方法:采用紫外-可见光谱法研究了SrCO3纳米结构的光学性质。Sr(NO3)2.6H2O和NaOH作为起始试剂。果糖(32.56-38.2%)和葡萄糖(28.54-31.3%)是蜂蜜中的主要碳水化合物,它们不仅参与稳定,而且在SrCO3纳米结构的生产中起到还原剂的作用。使用X射线衍射分析、傅立叶变换红外光谱、扫描电子显微镜和透射电子显微镜对所产生的纳米结构进行表征。结果:观察了合成方法和化学试剂对结构参数、晶粒大小、产物大小、形貌和抗氧化活性的影响。结论:蜂蜜可作为绿色封端剂和还原剂用于合成SrCO3纳米结构,这是一种利用光热剂共递送治疗剂的新型结构。此外,蜂蜜在未来具有巨大的诊断和治疗潜力。
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Biosynthesis of Srco3 nanostructures with honey as a green capping agent and reductant: photodynamic therapy
Objective (s): SrCO3 nanoparticles could be used as new biomedical sources in magnetic resonance imaging as a promising noninvasive imaging modality for the preoperative staging of breast cancer and monitoring of tumor response to therapy. The present study aimed to synthesize SrCO3 nanostructures using microwave irradiation in the presence of honey as a green capping agent and reductant. Materials and Methods: The optical properties of SrCO3 nanostructures were investigated using ultraviolet-visible (UV-Vis) spectroscopy. Sr(NO3)2.6H2O and NaOH were applied as the starting reagents. Fructose (32.56-38.2%) and glucose (28.54-31.3%), which were the main carbohydrates found in honey, were not only involved in stabilization, but they also acted as the reducing agents in the production of SrCO3 nanostructures. The produced nanostructures were characterized using X-ray diffraction analysis, Fourier transform infrared spectroscopy, scanning electron microscopy, and transmission electron microscopy.Results: Method of synthesis and chemical reagents were observed to affect the structural parameters, crystallite size, product size, morphology, and antioxidant activity. Conclusion: According to the results, honey could be used as a green capping agent and reductant for the synthesis of SrCO3 nanostructures as a novel structure to co-deliver therapeutic agents using photo-thermal agents. Moreover, honey has significant potential for diagnostic and therapeutic purposes in the future.
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来源期刊
Nanomedicine Journal
Nanomedicine Journal NANOSCIENCE & NANOTECHNOLOGY-
CiteScore
3.40
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0.00%
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0
审稿时长
12 weeks
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