孕妇弓形虫感染的血清阳性率及其危险因素

Q4 Immunology and Microbiology Boletin De Malariologia Y Salud Ambiental Pub Date : 2023-01-30 DOI:10.52808/bmsa.8e7.631.016
Alex Javier Criollo Rodríguez
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引用次数: 0

摘要

弓形虫病是一种由弓形虫引起的人畜共患寄生虫病,目前影响着世界近三分之一的人口,其中孕妇受影响最大。作为一个目标,建议确定孕妇弓形虫感染的血清流行率和危险因素。这项研究是定量的、描述性的、实验性的、横断面的。样本包括372名年龄在14岁至40岁之间的孕妇,她们在厄瓜多尔埃尔奥罗省的一家公立医院接受了妇科咨询。作为一种数据收集工具,一旦签署知情同意书,就应用社会人口学问卷,并在不使用抗凝剂的情况下收集静脉血样,用于血清学测定IgM和IgG抗T。通过捕获免疫酶测定法(ELISA)(IgM)和间接免疫酶测定(ELISA)法(IgG)检测弓形虫Vircell Microbiologists®。将数据存储在Microsoft Excel中,并使用SPSS统计包进行处理,以找到血清流行率值、95%置信区间(CI)和卡方(p<0.005)。结果,发现血清流行率为20.16%(75/372),其中受影响最严重的年龄组为24至28岁(25.23%),92%(69/72)存在IgG抗体,8%(6/72)存在IgM,婚姻状况与抗弓形虫抗体的存在之间存在显著的统计关联(p:0.0156),20.51%的人家里有猫,22.75%的人处理猫的粪便。在厄瓜多尔,有必要采取教育行动和战略来对抗弓形虫病。
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Seroprevalencia y factores de riesgo de la infección por Toxoplasma gondii en mujeres embarazadas
Toxoplasmosis is a parasitic zoonotic disease caused by Toxoplasma gondii, which currently affects almost a third of the world population, with the most pregnant being the most affected. As an objective, it was proposed to determine the seroprevalence and risk factors of Toxoplasma gondii infection in pregnant women. The study was quantitative, descriptive, experimental, cross-sectional. The sample consisted of 372 pregnant women between the ages of 14 and 40, who attended a gynecological consultation at a public hospital in the El Oro Province, Ecuador. As a data collection instrument, once the informed consent was signed, a sociodemographic questionnaire was applied and a venous blood sample was collected without anticoagulant for the serological determination of IgM and IgG anti-T. gondii through capture immunoenzymatic assay (ELISA) (IgM) and indirect immunoenzymatic assay (ELISA) (IgG) Vircell Microbiologists®. Data were stored in Microsoft Excel and processed with the SPSS statistical package to find seroprevalence values, 95% Confidence Intervals (CI) and Chi-square with p: <0.005. As a result, a seroprevalence of 20.16% (75/372) was found, where the most affected age group was 24 to 28 years (25.23%), 92% (69/72) presented IgG antibodies and 8% (6/72) IgM, a significant statistical association was found between marital status and the presence of antibodies against T. gondii (p: 0.0156), 20.51% had cats inside the house and 22.75% handled feces of the cats It is necessary to implement educational actions and strategies in the fight against toxoplasmosis in Ecuador.
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来源期刊
Boletin De Malariologia Y Salud Ambiental
Boletin De Malariologia Y Salud Ambiental INFECTIOUS DISEASES-PARASITOLOGY
CiteScore
0.40
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发文量
51
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