Elucidation of Anticancerous Potential of Plant Extracts Against Cervical Cancer

A human adult consists of about 1015 cells; which divide and differentiate in order to refurbish organs and tissues [1]. However, if the cells do not stop dividing, they may lead to cancer. Characteristically, cancer is an uncontrolled proliferation of cells which become structurally abnormal and possess the ability to detach them from a tumor and establish a new tumor at a remote site [2]. Every year over 200,000 people are diagnosed with cancer in the United Kingdom only, and approximately 120,000 die as a result of this disease [2]. According to the International Agency for Research on Cancer, in 2002, cancer killed more than 6.7 million people around the world and another 10.9 million new cases were diagnosed [3]. According to World Health Organization, cancer is the second cause of death globally after cardiovascular diseases. An estimated 8.2 million people die from cancer each year, that represents 13% of all deaths worldwide. Cancer basically results from the uncontrolled rapid division of malignant cells that grow beyond their usual limits. Unlike normal cells, cancerous cells do not respond to the controlling signals and consequently, they grow and divide in an uncontrolled manner, infecting normal tissues and organs. There can be many different types of cancers. The type of the cell from where the tumors originate classifies the cancers. Cancers derived from epithelial cells of breast, prostate, lung, pancreas and colon, cause approximately 90% of all human deaths from cancer; lymphomas are cancers of the immune organs such as spleen, white blood cells and lymph glands; leukemias causes the cancers of blood forming bone marrow; while sarcomas are cancers of fibrous connective tissues of bone, cartilage, fat tissue, muscle and neurons; and germ cell tumors are derived from pluripotent stem cells presented in the testicles and ovary. Early detection and effective treatment can help to increase survival rates of cancer patients. So therefore, deliberative plans are needed to improve prevention and treatment of cancer. As we all know cancer rates continue to rise, particularly in the developed world, becoming one of the leading public health problems in many countries [4]. Many of the cancers are associated with longevity, and the possibility of their appearance increases as the life expectancy of individuals increases [5]. Cervical cancer (CC) is a principal cause of death in women in the whole world [6-8]. The research done up to date indicated that this cancer Abstract