{"title":"加木方可降低轻度高胆固醇血症患者血浆胆固醇","authors":"Z. Zulkarnain, A. Triyono, F. Novianto","doi":"10.22435/hsji.v9i2.808","DOIUrl":null,"url":null,"abstract":"Latar belakang: Pengobatan hiperkolesterolemia sering berlangsung seumur hidup sehingga menyebabkanpenderita meninggalkan obat kimia dan memilih obat herbal. Penelitian ini merupakan uji klinik yang bertujuanuntuk mengetahui khasiat dari formula jamu antikolesterol yang terdiri dari daun jati belanda, daun jati cina,daun tempuyung, daun teh hijau, rimpang temulawak, rimpang kunyit dan herba meniran dalam menurunkankadar kolesterol darah sebagai bagian dari program Saintifikasi Jamu. \nMetode: Penelitian ini menggunakan metode kuasi eksperimental dengan desain pre dan post. Jumlah subjek50 pasien dengan hiperkolesterolemia ringan yang memenuhi kriteria inklusi. Penelitian dilakukan di RumahRiset Jamu (RRJ) Hortus Medicus Tawangmangu pada bulan September sampai Desember 2014. Uji statistikyang digunakan adalah uji t berpasangan dengan bantuan program SPSS 16. \nHasil: Formula jamu antihiperkolesterol yang diminum setiap hari selama 28 hari mampu menurunkan rataratakadar kolesterol plasma subjek dari 212.42 mg / dl menjadi 196.6 mg / dl. Uji t test berpasangan didapatkanhasil p<0,05 yang berarti ada perbedaan rerata kadar kolesterol sebelum dan sesudah pemberian jamu.Kesimpulan: Formula jamu antihiperkolesterol mampu menurunkan kadar kolesterol plasma pasiendengan hiperkolesterolemia ringan pada pemberian selama 28 hari. (Health Science Journal of Indonesia2018;9(2):87-92) \nKata kunci: hiperkosterolemia, jamu, saintifikasi jamu \nAbstract \nBackground: Treatment of hypercholesterolemia often lasts a lifetime, therefore patients leavechemical drugs and choose herbal medicines. The aim of this clinical study is to evaluate the efficacy ofantihiperkolesterol jamu formula consists of Guazuma ulmifolia leaves, Cassia senna leaves, Sonchusarvensis leaves, Camellia sinensis leaves, Curcuma xanthorrhiza rhizomes, Curcuma longa rhizomes andPhyllanthus niruri herbs to lowering cholesterol plasma level as part of Saintifikasi Jamu program. \nMethods: This study was a quasi-experimental with pre and post test design. The total subjects were 50patients with mild hypercholesterolemia who met the inclusion criteria. The research took place at RRJ‘Hortus Medicus’ Tawangmangu between September to December 2014. The data were analyzed using apaired t-test with SPSS 16 software. \nResults: Results showed jamu anticholesterol formula which is taken every day for 28 days lowered themean of cholesterol plasma level of 212.42 mg / dl to 196.6 mg / dl. Paired t test at 95% confidence levelacquired p value <0.05, showed that there is significant differences in the mean cholesterol level subjectsbefore and after the study. \nConclusion: The administration of jamu antihypercholesterol formula for 28 days could reduce plasmacholesterol level in subjects with mild hypercholesterolemia. (Health Science Journal of Indonesia2018;9(2):87-92) \nKeywords: hypercholesterolemia, Jamu, Saintifikasi Jamu","PeriodicalId":30666,"journal":{"name":"Health Science Journal of Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Jamu formula could reduce plasma cholesterol patients with mild Hypercholesterolemia\",\"authors\":\"Z. Zulkarnain, A. Triyono, F. Novianto\",\"doi\":\"10.22435/hsji.v9i2.808\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Latar belakang: Pengobatan hiperkolesterolemia sering berlangsung seumur hidup sehingga menyebabkanpenderita meninggalkan obat kimia dan memilih obat herbal. Penelitian ini merupakan uji klinik yang bertujuanuntuk mengetahui khasiat dari formula jamu antikolesterol yang terdiri dari daun jati belanda, daun jati cina,daun tempuyung, daun teh hijau, rimpang temulawak, rimpang kunyit dan herba meniran dalam menurunkankadar kolesterol darah sebagai bagian dari program Saintifikasi Jamu. \\nMetode: Penelitian ini menggunakan metode kuasi eksperimental dengan desain pre dan post. Jumlah subjek50 pasien dengan hiperkolesterolemia ringan yang memenuhi kriteria inklusi. Penelitian dilakukan di RumahRiset Jamu (RRJ) Hortus Medicus Tawangmangu pada bulan September sampai Desember 2014. Uji statistikyang digunakan adalah uji t berpasangan dengan bantuan program SPSS 16. \\nHasil: Formula jamu antihiperkolesterol yang diminum setiap hari selama 28 hari mampu menurunkan rataratakadar kolesterol plasma subjek dari 212.42 mg / dl menjadi 196.6 mg / dl. Uji t test berpasangan didapatkanhasil p<0,05 yang berarti ada perbedaan rerata kadar kolesterol sebelum dan sesudah pemberian jamu.Kesimpulan: Formula jamu antihiperkolesterol mampu menurunkan kadar kolesterol plasma pasiendengan hiperkolesterolemia ringan pada pemberian selama 28 hari. (Health Science Journal of Indonesia2018;9(2):87-92) \\nKata kunci: hiperkosterolemia, jamu, saintifikasi jamu \\nAbstract \\nBackground: Treatment of hypercholesterolemia often lasts a lifetime, therefore patients leavechemical drugs and choose herbal medicines. The aim of this clinical study is to evaluate the efficacy ofantihiperkolesterol jamu formula consists of Guazuma ulmifolia leaves, Cassia senna leaves, Sonchusarvensis leaves, Camellia sinensis leaves, Curcuma xanthorrhiza rhizomes, Curcuma longa rhizomes andPhyllanthus niruri herbs to lowering cholesterol plasma level as part of Saintifikasi Jamu program. \\nMethods: This study was a quasi-experimental with pre and post test design. The total subjects were 50patients with mild hypercholesterolemia who met the inclusion criteria. The research took place at RRJ‘Hortus Medicus’ Tawangmangu between September to December 2014. The data were analyzed using apaired t-test with SPSS 16 software. \\nResults: Results showed jamu anticholesterol formula which is taken every day for 28 days lowered themean of cholesterol plasma level of 212.42 mg / dl to 196.6 mg / dl. Paired t test at 95% confidence levelacquired p value <0.05, showed that there is significant differences in the mean cholesterol level subjectsbefore and after the study. \\nConclusion: The administration of jamu antihypercholesterol formula for 28 days could reduce plasmacholesterol level in subjects with mild hypercholesterolemia. (Health Science Journal of Indonesia2018;9(2):87-92) \\nKeywords: hypercholesterolemia, Jamu, Saintifikasi Jamu\",\"PeriodicalId\":30666,\"journal\":{\"name\":\"Health Science Journal of Indonesia\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-12-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Health Science Journal of Indonesia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22435/hsji.v9i2.808\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Health Science Journal of Indonesia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22435/hsji.v9i2.808","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
摘要
背景:高胆固醇治疗通常持续一生,使患者放弃化学药物并选择草药。这项研究是一项临床试验,旨在研究由荷兰柚木、中国柚木叶、铁杉叶、绿茶叶、藏红花、藏红花和草本植物配方的有效降低作为草药认证项目的一部分的抗胆固醇配方。方法:本研究采用预前和后设计的实验准体方法。测试对象50名患者患有轻微胆固醇异常,符合包裹体标准。2014年9月至12月,在草本植物研究(RRJ) Hortus Medicus Tawangmangu进行了研究。使用的统计结果是在SPSS 16项目的帮助下进行t配对测试。结果:一种每天服用28天的抗胆固醇草本植物配方,可以将血浆成分从12.42毫克/ dl降低到196.6毫克/ dl。t测试与p< 0.05的结果相匹配,这意味着在草药治疗前和治疗后胆固醇水平存在差异。结论:一种抗胆固醇草药配方可以通过适度的胆固醇喂养28天来降低病人的血浆胆固醇水平。(卫生科学杂志《印尼2018年》;9(2):87-92)关键词:夸张,草药,批准草药摘要的科学事实:十年的治疗左心肌酸毒品和草药选择。这临床研究之aim to evaluate The efficacy ofantihiperkolesterol草药配方的公司Guazuma ulmifolia树叶,树叶凯西塞纳树叶,树叶Sonchusarvensis茶花sinensis, Curcuma xanthorrhiza rhizomes, Curcuma longa rhizomes andPhyllanthus niruri全书到美国等离子lowering过高水平Saintifikasi草药项目的一部分。方法:这个研究是一种试验性的试验。总共有50名患者,他们的体重都是高胆固醇的。2014年9月至12月间数据是用SPSS 16软件对t测试进行分析。回收:回收的抗cholesterol配方每天耗时28天,其血浆浓度为212.42毫克/ dl至196.6毫克/ dl。95%的确认性levelacquired p值<0.05,表明在研究之前和之后的平均选择水平上存在显著差异。结论:28天抗高胆固醇草药配方的行政管理可以在测试中减少可的松醇水平。(印尼健康科学杂志:9(2):Keywords:高血压,草药,草药认证
Jamu formula could reduce plasma cholesterol patients with mild Hypercholesterolemia
Latar belakang: Pengobatan hiperkolesterolemia sering berlangsung seumur hidup sehingga menyebabkanpenderita meninggalkan obat kimia dan memilih obat herbal. Penelitian ini merupakan uji klinik yang bertujuanuntuk mengetahui khasiat dari formula jamu antikolesterol yang terdiri dari daun jati belanda, daun jati cina,daun tempuyung, daun teh hijau, rimpang temulawak, rimpang kunyit dan herba meniran dalam menurunkankadar kolesterol darah sebagai bagian dari program Saintifikasi Jamu.
Metode: Penelitian ini menggunakan metode kuasi eksperimental dengan desain pre dan post. Jumlah subjek50 pasien dengan hiperkolesterolemia ringan yang memenuhi kriteria inklusi. Penelitian dilakukan di RumahRiset Jamu (RRJ) Hortus Medicus Tawangmangu pada bulan September sampai Desember 2014. Uji statistikyang digunakan adalah uji t berpasangan dengan bantuan program SPSS 16.
Hasil: Formula jamu antihiperkolesterol yang diminum setiap hari selama 28 hari mampu menurunkan rataratakadar kolesterol plasma subjek dari 212.42 mg / dl menjadi 196.6 mg / dl. Uji t test berpasangan didapatkanhasil p<0,05 yang berarti ada perbedaan rerata kadar kolesterol sebelum dan sesudah pemberian jamu.Kesimpulan: Formula jamu antihiperkolesterol mampu menurunkan kadar kolesterol plasma pasiendengan hiperkolesterolemia ringan pada pemberian selama 28 hari. (Health Science Journal of Indonesia2018;9(2):87-92)
Kata kunci: hiperkosterolemia, jamu, saintifikasi jamu
Abstract
Background: Treatment of hypercholesterolemia often lasts a lifetime, therefore patients leavechemical drugs and choose herbal medicines. The aim of this clinical study is to evaluate the efficacy ofantihiperkolesterol jamu formula consists of Guazuma ulmifolia leaves, Cassia senna leaves, Sonchusarvensis leaves, Camellia sinensis leaves, Curcuma xanthorrhiza rhizomes, Curcuma longa rhizomes andPhyllanthus niruri herbs to lowering cholesterol plasma level as part of Saintifikasi Jamu program.
Methods: This study was a quasi-experimental with pre and post test design. The total subjects were 50patients with mild hypercholesterolemia who met the inclusion criteria. The research took place at RRJ‘Hortus Medicus’ Tawangmangu between September to December 2014. The data were analyzed using apaired t-test with SPSS 16 software.
Results: Results showed jamu anticholesterol formula which is taken every day for 28 days lowered themean of cholesterol plasma level of 212.42 mg / dl to 196.6 mg / dl. Paired t test at 95% confidence levelacquired p value <0.05, showed that there is significant differences in the mean cholesterol level subjectsbefore and after the study.
Conclusion: The administration of jamu antihypercholesterol formula for 28 days could reduce plasmacholesterol level in subjects with mild hypercholesterolemia. (Health Science Journal of Indonesia2018;9(2):87-92)
Keywords: hypercholesterolemia, Jamu, Saintifikasi Jamu