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Intake of kidney bean (phaseolus vulgaris) extract as postpartum blues management 服用芸豆提取物治疗产后忧郁
Pub Date : 2022-01-10 DOI: 10.22435/hsji.v12i2.4938
Desta Ayu Cahya Rosyida, Nina Nikmah, Khoiriyah Noviastuti
Background: Postpartum blues is common in postpartum Mother with more prone to crying, more anxious, often unstable and more emotional than usual. Zinc supplementation is one of the methods needed for postpartum blues conditions. Kidney bean (phaseolus vulgaris) extract has the highest zinc content. This study aimed to examine the effect of intake kidney bean extract (phaseolus vulgaris) as a zinc source as management mother with Postpartum Blues Methods: Quantitative study with an experimental study design (Quasi Experiment Design) with a Pre and Post-test Control Group Design. The instrument used to measure the mood of a mother after childbirth was EPDS (Edinburgh Post-Partum Depression Scale). The total sample was 68 mothers who experienced postpartum blues in Ngerandu Ponorogo primary health care. The Mann-Whitney was used to analyse and find out the difference in mood improvement before and after the intervention in the experimental group and the control group. Results: The results showed that there was a statistically significant difference in mood levels of mothers with postpartum blues before and after intervention (p value of 0.001 (<0.005). This result indicated that intake of kidney bean (Phaseolus vulgaris) extract had an effect on the mood level of mothers with postpartum blue. Conclusion: Intake of kidney bean (phaseolus vulgaris) extract on the incidence of postpartum blues possibly improvement mood in the experimental group after the treatment for 1 month. Keywords: kidney bean (phaseolus vulgaris) extract, postpartum blues, postpartum mother   Abstrak Latar belakang: Postpartum blues umum terjadi pada ibu postpartum dengan tanda sering menangis, khawatir yang berlebihan, emosional yang tidak stabil. Suplementasi zinc merupakan salah satu metode yang dibutuhkan untuk kondisi postpartum blues. Ektrak kacang merah (phaseolus vulgaris) memiliki sumber nutrisi zinc yang tinggi, Penelitian ini bertujuan untuk menguji efek konsumsi ekstrak kacang merah (phaseolus vulgaris) sebagai sumber zinc sebagai manajemen ibu dengan postpartum blues Metode: Penelitian kuantitatif dengan design Quasi Experiment pre dan post control grup. Instrumen pengukur mood ibu setelah melahirkan adalah EPDS (Edinburgh Post-Partum Depression Scale). Total Sampel 68 ibu yang mengalami postpartum blues di Puskesmas Ngerandu Ponorogo. Analisis statistik menggunakan Mann-Whitney untuk menemukan perbedaan perubahan mood ibu postpartum blues sebelum dan sesudah dilakukan intervensi pada grup intervensi dan kontrol. Hasil: Hasil menunjukkan bahwa terdapat perbedaan signifikan tingkat mood ibu dengan postpartum blues sebelum dan sesudah dilakukan intervensi (p : 0,001 (<0,005). Hasil mengindikasikan bahwa konsumsi ekstrak kacang merah (phaseolus vulgaris) memiliki efek pada tingkat mood ibu yang sedang mengalami postpartum blues. Kesimpulan: Konsumsi ekstrak kacang merah (phaseolus vulgaris) pada ibu postpartum blues memungkinkan untuk perubahan mood pada grup
背景:产后忧郁在产后母亲中很常见,她们比平时更容易哭泣、更焦虑、更不稳定、更情绪化。补锌是产后忧郁所需的方法之一。芸豆提取物的锌含量最高。本研究旨在检验摄入芸豆提取物作为锌源作为产后忧郁管理母亲的效果。方法:实验研究设计的定量研究(准实验设计)和试验前后对照组设计。用于测量母亲产后情绪的仪器是EPDS(爱丁堡产后抑郁量表)。总样本为68名在Ngerandu Ponorogo初级卫生保健中心经历产后忧郁的母亲。采用Mann-Whitney量表分析实验组和对照组干预前后情绪改善的差异。结果:干预前后产后忧郁母亲情绪水平差异有统计学意义(p值0.001(<0.005),说明芸豆提取物的摄入对产后忧郁母亲的情绪水平有影响。结论:实验组服用芸豆提取物对产后忧郁的发生率可能改善治疗1个月后的情绪。关键词:芸豆提取物;产后忧郁;产后母亲补锌是产后忧郁所需的方法之一。红豆提取物具有较高的锌营养来源,本研究的目的是检验红豆提取物作为锌来源对产后忧郁母亲的管理效果。方法:采用设计准实验前后对照组进行定量研究。测量母亲产后情绪的仪器是爱丁堡产后抑郁量表。Ponorogo Ngerandu中心的68名产后忧郁母亲的总样本。采用Mann-Whitney统计分析法,发现干预组和对照组干预前后母亲产后忧郁情绪的差异。结果:结果显示,干预前后产后忧郁母亲的情绪水平有显著差异(p:0.001(<0.005)。结果表明,食用红豆提取物对产后忧郁母亲的情绪水平有影响。结论:产后忧郁母亲食用红豆提取物可使干预组在治疗1个月后情绪发生变化。关键词:寻常相,产后忧郁,产后妈妈
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引用次数: 0
The relationship of smoking duration, sleep disorders, and nutritional status of Indonesian adult men: data analysis of the 2014 Indonesian Family Life Surve 印尼成年男性吸烟时间、睡眠障碍和营养状况的关系:2014年印尼家庭生活调查的数据分析
Pub Date : 2021-12-16 DOI: 10.22435/hsji.v12i2.5243
Relawantria Harlianti, Trias Mahmudiono, D. Atmaka, S. Helmyati, Mira Dewi, C. T. Yuniar
Background: In Indonesia, the prevalence of smoking is increasing from year to year and can cause various health problems, such as sleep disorders and affect a person's nutritional status. So, in this study, the relationship between smoking duration, sleep disturbances, and nutritional status in men aged 26–45 years will be investigated using secondary data from the 2014 Indonesia Family Live Survey (IFLS). Methods: The 2014 secondary data from the fifth waves of the IFLS were used for analysis. All 5,379 data of men aged 26–45 years who provided anthropometric, smoking duration, and sleep disorders were included in the study. The Chi-Square test was used to examine the relationship between smoking duration, sleep disorders, and nutritional status in men aged 26 – 45 years. Furthermore, the Multinomial Logistics Regression test is carried out to determine the variables that have the strongest influence. Results: Based on the results of statistical tests conducted, it was found that the majority of respondents had a smoking duration of 11-20 years, of which  27.2% of respondents did not experience sleep disorders and 25.4% had sleep disorders. The nutritional status of respondents with a smoking duration of 11-20 years is normal as many as 35% of respondents and at least 0.5% of respondents have underweight nutritional status with smoking duration <5 years. Furthermore, the test results of the relationship between smoking duration and sleep disturbances obtained p-value = 0.03 and the relationship between smoking duration and nutritional status obtained p-value <0.01. Conclusion: Smoking duration was associated with sleep disorder and overweight nutritional status in men aged 26 – 45 years. Keywords: smoking duration, sleep disorder, nutritional status, tobacco use, sleeping sickness   Abstrak Latar belakang: Di Indonesia, prevalensi merokok semakin meningkat dari tahun ke tahun dan dapat menyebabkan berbagai permasalahan kesehatan, seperti gangguan tidur serta mempengaruhi status gizi seseorang. Sehingga pada penelitian ini akan diteliti hubungan antara durasi merokok, gangguan tidur, dan status gizi pada pria berusia 26–45 tahun menggunakan data sekunder dari Indonesia Family Live Survey (IFLS) tahun 2014. Metode: Analisis dari data sekunder gelombang kelima IFLS tahun 2014. Semua 5.379 data pria berusia 26–45 tahun yang memiliki kelengkapan data antropometri, kebiasaan merokok, dan gangguan tidur diikutkan dalam penelitian. Uji Chi-Square digunakan untuk menguji hubungan antara durasi merokok, gangguan tidur, dan status gizi pada pria berusia 26 – 45 tahun. Selanjutnya uji Regresi Logistik Multinomial dilakukan untuk mengetahui variabel yang memiliki pengaruh paling kuat. Hasil: Berdasarkan hasil dari uji statistik yang dilakukan, didapatkan bahwa mayoritas responden memiliki durasi merokok selama 11-20 tahun, dimana sebanyak 27.2% responden tidak mengalami gangguan tidur dan 25.4% mengalami gangguan tidur. Status gizi paling banyak ya
背景:在印度尼西亚,吸烟的流行率逐年上升,并可能导致各种健康问题,如睡眠障碍和影响一个人的营养状况。因此,在本研究中,将使用2014年印度尼西亚家庭生活调查(IFLS)的二手数据调查26-45岁男性吸烟持续时间、睡眠障碍和营养状况之间的关系。方法:采用2014年IFLS第五波二次资料进行分析。5379名年龄在26-45岁之间的男性提供了人体测量、吸烟持续时间和睡眠障碍的数据都被纳入了研究。采用卡方检验检验26 - 45岁男性吸烟持续时间、睡眠障碍和营养状况之间的关系。此外,进行多项logistic回归检验,以确定影响最强的变量。结果:根据统计检验的结果,大多数受访者的吸烟时间为11-20年,其中27.2%的受访者没有睡眠障碍,25.4%的受访者有睡眠障碍。吸烟时间为11-20年的被调查者营养状况正常的比例高达35%,吸烟时间<5年的被调查者营养状况不足的比例至少为0.5%。吸烟持续时间与睡眠障碍关系的检验结果p值= 0.03,吸烟持续时间与营养状况关系的检验结果p值<0.01。结论:吸烟持续时间与26 ~ 45岁男性的睡眠障碍和超重营养状况有关。关键词:吸烟时间,睡眠障碍,营养状况,烟草使用,昏睡病。摘要:印度尼西亚,流行病学,流行病学,流行病学,流行病学,流行病学,流行病学,流行病学。sehinga pada penelitian ini akan diteliti hubungan antara durasi merokok, gangguan tidur, danstatus gizi pada pria berusia 26-45, tahun menggunakan数据收集于印度尼西亚家庭生活调查(IFLS), 2014年1月。方法:根据2014年中国国际地理信息系统(IFLS)的数据进行分析。[3] [1] [1] [1] [1] [1] [1] [1] [4] [1] [1] [4] [1] [4] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1]Uji Chi-Square digunakan untuk menguji hubungan antara durasi merokok, gangguan tidur, dan status gizi pada pria beria 26 - 45 tahun。[3][1][1][1][1][1][1][1][2][1][1]。Hasil: Berdasarkan Hasil dari uji statistics yang dilakukan, didapatkan bahwa mayoritas respondeniliki durasi merokok selama 11-20 tahun, dimana sebanyak 27.2% respondenak mengalami gangguan tidur和25.4% mengalami gangguan tidur。状态gizi paling banyak yang dimiliki oleh应答dengan durasi merokok selama 11-20 tahun adalah正常sebanyak 35%应答dengan paling sedikit sebanyak 0.5%应答memiliki状态gizi体重过轻dengan durasi merokok <5 tahun。Selanjutnya hasil uji hubungan antara durasi merokok dengan gangguan tidur didapatkan nilai p值=0.03但hubungan antara durasi merokok dengan status gizi didapatkan nilai p值<0.01。kespulan: Durasi merokok berhubungan dengan gangguan tidur dan status gizi超重帕达·拉基·拉基·乌苏亚26 - 45 tahun。Kata kunci: durasi merokok, gangguan tidur, status gizi, penggunaan tembakau, penyakit tidur
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引用次数: 0
Interferon gamma concentration in diabetes mellitus and dyslipidemia patient 糖尿病和血脂异常患者的干扰素浓度
Pub Date : 2021-12-16 DOI: 10.22435/hsji.v12i2.4290
Nelly Marissa, Marlinda Marlinda, Maulidar Maulidar, Veny Wilya, Nur Ramadhan, Zain Hadifah
Background: Patient with diabetes mellitus (DM) occurs chronic inflammation by characterized a decreased concentration of various cytokinin types. This causes changes in the body’s immunity so that can be easier in having an infection. One of the most important cytokines against infection is IFN-γ. This study aimed to determine IFN-γ concentration in DM and dyslipidemia patients. Metode: An amount of 234 people who received treatment at the health center in Banda Aceh in 2019 were included in this study. From each respondent, 5 ml of blood was taken to check fasting blood glucose, triglycerides, high-density lipoproteins (HDL), and interferon-gamma (IFN-γ). Test of fasting blood glucose, triglycerides, HDL was carried out using the colorimetric enzymatic method. The IFN-γ protein concentration was examined using the sandwich enzyme-linked immunosorbent assay (ELISA) technique. Result: IFN-γ concentration in the non-DM group was higher than in the DM group. There was a significant difference between the average IFN-γ concentration in the non-DM group compared with the DM group (p = 0.000). All DM patients had increased fasting blood glucose, most had hypertriglycerides, but HDL levels were normal. The fasting blood glucose group <126 mg / dl had a higher IFN-γ concentration than the group with fasting blood glucose levels ≥126 mg / dl. There was a significant difference in the concentration of IFN-γ between the two groups (p = 0.000). The group with triglyceride levels <150 mg / dl had lower IFN-γ levels than the group with triglyceride levels ≥ 150 mg / dl. There was a significant difference between the average IFN-γ concentration between those groups (p = 0.000). The fasting blood glucose levels ≥126 mg / dl and triglycerides levels ≥ 150 mg / dl had higher IFN-γ concentration than the group who had fasting blood glucose levels ≥126 mg / dl and triglycerides levels < 150 mg / dl. Conclusion: There are differences in IFN-γ concentrations in people with DM, increased fasting blood glucose and dyslipidemia compared to normal people. Keywords: IFN-γ, diabetes mellitus, dyslipidemia   Abstrak Latar belakang: Penderita diabetes mellitus (DM) dan dyslipidemia mengalami inflamasi kronik yang ditandai dengan perubahan konsentrasi berbagai sitokin. Hal ini yang menyebabkan perubahan imunitas tubuh sehingga mudah mengalami infeksi. Salah satu sitokin yang paling berperan terhadap infeksi adalah interferon gamma (IFN-γ). Penelitian ini bertujuan untuk memeriksa konsentrasi IFN-γ pada penderita DM dan dislipidemia. Metode: Sebanyak 234 orang yang melakukan pengobatan di puskesmas di Kota Banda Aceh pada tahun 2019 diikutsertakan dalam penelitian ini. Dari setiap responden dilakukan pengambilan darah sebanyak 5 ml untuk dilakukan pemeriksaan kadar gula darah puasa (KGD P), trigliserida, high density lipoprotein (HDL), dan inrferon- gamma (IFN-γ). Pemeriksaan KGD, trigliserida, HDL dilakukan dengan metode enzimatik kolorimetrik. Pemeriksaan konsentrasi
背景:糖尿病(DM)患者以各种细胞分裂素浓度降低为特征发生慢性炎症。这会导致身体免疫力的变化,从而更容易感染。抗感染最重要的细胞因子之一是IFN-γ。本研究旨在测定糖尿病和血脂异常患者体内IFN-γ的浓度。方法:2019年在班达亚齐卫生中心接受治疗的234人被纳入本研究。从每个应答者身上抽取5毫升血液来检测空腹血糖、甘油三酯、高密度脂蛋白(HDL)和干扰素-γ (IFN-γ)。采用比色法测定空腹血糖、甘油三酯、高密度脂蛋白。采用夹心酶联免疫吸附试验(ELISA)技术检测IFN-γ蛋白浓度。结果:非DM组IFN-γ浓度明显高于DM组。非DM组IFN-γ平均浓度与DM组比较差异有统计学意义(p = 0.000)。所有糖尿病患者均有空腹血糖升高,大多数患者有高甘油三酯,但高密度脂蛋白水平正常。空腹血糖<126 mg / dl组IFN-γ浓度高于空腹血糖≥126 mg / dl组。两组间IFN-γ浓度差异有统计学意义(p = 0.000)。甘油三酯水平<150 mg / dl组IFN-γ水平低于甘油三酯水平≥150 mg / dl组。各组间IFN-γ平均浓度差异有统计学意义(p = 0.000)。空腹血糖≥126 mg / dl、甘油三酯≥150 mg / dl组IFN-γ浓度高于空腹血糖≥126 mg / dl、甘油三酯< 150 mg / dl组。结论:糖尿病患者IFN-γ浓度、空腹血糖升高、血脂异常与正常人相比存在差异。【关键词】IFN-γ,糖尿病,血脂异常【关键词】糖尿病,糖尿病,血脂异常【关键词】糖尿病,糖尿病,血脂异常;我是说,我是说,我是说,我是说,我是说,我是说,我是说,我是说。研究结果表明:Salah是影响阳平的主要因素,与干扰素γ (IFN-γ)有关。Penelitian ini bertujuan untuk memiksa konsentrasi IFN-γ与糖尿病和二脂血症有关。方法:Sebanyak 234 orang yang melakukan pengobatan di puskesmas di Kota Banda Aceh pada tahun 2019 diikutsertakan dalam penelitian ini。dilakukan pengambilan darah sebanyak 5 ml untuk dilakukan permeriksaan kadar gula darah puasa (KGD P),甘油三酯,高密度脂蛋白(HDL),丹干扰素-γ (IFN-γ)。Pemeriksaan KGD, trigliserida, HDL, dilakukan denengan方法,免疫比色法。酶联免疫吸附试验(ELISA);Hasil: Konsentrasi IFN-γ pada kelompok non-DM lebih tinggi dibandingkan dengan kelompok DM. Terdapat perbedaan and bermakna rata-rata Konsentrasi IFN-γ pada kelompok non-DM dibandingkan dengan kelompok DM (p= 0000)。Semua penderita DM mengalami peningkatan KGD P, sebagian besar mengalami hipertriglierida, namun kadar HDL正常。KGD P < 126mg /dl; KGD P < 126mg /dl; KGD P < 126mg /dl; KGD P < 126mg /dl;Terdapat perbedaa和bermakna perbedaa和konsentrasi IFN-γ antar kedua kelompok tersebut (p= 000)。Kelompok dengan kadar trigliserida < 150mg /dl memiliki kadar IFN-γ lebih rendah dibandingkan Kelompok dengan kadar trigliserida≥150mg /dl。Terdapat perbedaa和bermakna antara rata-rata konsentrasi konsentrasi IFN-γ antar kedua kelompok tersebut (p= 000)。巴旦木KGD P≥126 mg/dl丹甘油三酯≥150 mg/dl memiliki kadar IFN-γ yang lebih tinggi dibandingkan dengan kelpok KGD P≥126 mg/dl namun trigliserida <150 mg/dl。Terdapat perbedaa和bermakna antara rata-rata konsentrasi konsentrasi IFN-γ antar kedua kelompok tersebut (p= 000)。研究结果表明:1型糖尿病患者IFN-γ与糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病。Kata kunci: IFN-γ,糖尿病,二脂血症。
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引用次数: 1
Optimization of multiplex real-time RT-PCR for respiratory syncytial viruses detection 多重实时RT-PCR检测呼吸道合胞病毒的优化
Pub Date : 2021-12-16 DOI: 10.22435/hsji.v12i2.5529
A. Agustiningsih
Abstract Background: Multiplex real-time RT-PCR (rRT-PCR) is a fast, sensitive and specific test to detect more than one target in single PCR reaction. In this study we developed multiplex rRT-PCR for RSV-A and RSV-B since those viruses are the most common pathogen found in respiratory tract. However, in order to gain optimal reaction for RSV-A and RSV-B detection, the optimization of primers and probes specific for RSV-A and RSV B are needed. Method: The primers and probes of multiplex rRT-PCR for RSV-A and RSV-B were selected and optimized utilizing PerlPrimer software and BLAST to analyze the secondary structures and specificity, respectively. Further testing of selected primers and probes for rRT-PCR was done using annealing temperature based on in silico analysis as mentioned above. This includes sensitivity testing with the utilization of synthesized DNA of RSV-A and RSV-B and specificity testing targeting the common viruses found in respiratory tract. Results: The primer set and probes selected for RSV-A and RSV-B detection were specific only for RSV-A and RSV-B and showed no secondary structure. Based on primer and probe criteria for rRT-PCR such as annealing temperature, no secondary structure formed, % GC content and limit of detection, the multiplex rRT-PCR test using selected primers and probes was able to detect synthesized DNA of RSV-A and RSV-B. Conclusion: Multiplex rRT-PCR that employing primer sets and probes targeted N gene of RSV-A and RSV-B in this study were able to be detect RSV-A and RSV-B in single PCR reaction. Keyword: Multiplex, real-time RT-PCR, RSV-A, RSV-B   Abstrak Latar belakang: Multiplex real-time RT-PCR (rRT-PCR) merupakan metode yang cepat, sensitif dan spesifik untuk mendeteksi lebih dari satu target pathogen dalam satu reaksi PCR. Penelitian ini bertujuan untuk mengembangkan multiplex rRT-PCR virus RSV-A dan RSV-B yang merupakan patogen yang paling sering ditemukan di saluran pernafasan. Optimisasi dari primer dan probe dalam multiplex rRT-PCR diperlukan untuk mendapatkan reaksi yang optimal dalam deteksi virus RSV-A dan RSV-B. Metode: Primer dan probe untuk multiplex rRT-PCR RSV-A dan RSV-B dipilih dan dioptimasi menggunakan software PerlPrimer dan BLAST untuk menganalisis adanya struktur sekunder serta spesifisitas dari primer dan probe. Uji multiplex rRT-PCR dilanjutkan berdasarkan suhu annealing berdasarkan hasil analisis menggunakan PerlPrimer. Uji sensitifitas dilakukan dengan menggunakan DNA sintetis dari RSV-A dan RSV-B dan uji spesifisitas dilakukan dengan mengetes primer dan probe terhadap virus-virus lain yang umumnya ditemukan di saluran pernafasan. Hasil: Primer dan probe yang dikembangkan pada penelitian ini tidak membentuk struktur sekunder dan spesifik mengamplifikasi hanya RSV-A dan RSV-B. Berdasarkan kriteria primer dan probe untuk digunakan dalam rRT-PCR yaitu suhu annealing, tidak adanya pembentukan struktur sekunder, % GC content serta detection limit, uji multiplex rRT-PCR yan
背景:多重实时RT-PCR (multiple real-time RT-PCR, rRT-PCR)是一种快速、灵敏、特异的检测方法,可在单次PCR反应中检测多个靶点。由于RSV-A和RSV-B是呼吸道中最常见的病原体,因此本研究建立了RSV-A和RSV-B的多重rRT-PCR。然而,为了获得检测RSV- a和RSV-B的最佳反应,需要对RSV- a和RSV-B特异性的引物和探针进行优化。方法:选择RSV-A和RSV-B多重rRT-PCR引物和探针,分别利用PerlPrimer软件和BLAST对引物和探针进行优化,分析二级结构和特异性。对rRT-PCR选择的引物和探针进行进一步的测试,根据上文的硅分析使用退火温度。这包括利用RSV-A和RSV-B的合成DNA进行敏感性测试,以及针对呼吸道常见病毒的特异性测试。结果:选择的RSV-A和RSV-B检测引物组和探针仅对RSV-A和RSV-B具有特异性,且无二级结构。根据rRT-PCR的引物和探针标准,如退火温度、未形成二级结构、GC含量%和检出限等,选择引物和探针进行多重rRT-PCR检测,能够检测到RSV-A和RSV-B的合成DNA。结论:本研究采用引物组和探针对RSV-A和RSV-B的N基因进行多重rRT-PCR,可在单次PCR反应中检测到RSV-A和RSV-B。【关键词】多重实时RT-PCR (rRT-PCR), RSV-A, RSV-B摘要:多重实时RT-PCR (rRT-PCR), merupakan方法,敏感和特异的检测方法;该病毒为RSV-A型和RSV-B型杨氏病致病菌,致病菌为杨氏病。Optimisasi dari引物dan探针dalam多重rRT-PCR diperlukan untuk mendapatkan reaksi yang最优dalam检测RSV-A和RSV-B病毒。Metode:丹引物探针为她多路复用rrt - pcr RSV-A丹RSV-B dipilih丹dioptimasi menggunakan软件PerlPrimer丹爆炸为她menganalisis adanya合写sekunder舒达spesifisitas达里语底漆丹探针。Uji多重rRT-PCR dilanjutkan berdasarkan suhu退火berdasarkan hasil分析menggunakan PerlPrimer。乌吉敏敏性dilakukan dengan menggunakan DNA sinintetis RSV-A和RSV-B,乌吉种特异性dilakukan dengan mengetes引物和探针terhadap病毒-病毒株yang umumnya diemukan di saluran pernafasan。【中文译文】:引物单探针yang dikembangkan pada penelitian ini在一种特殊的RSV-A和RSV-B下进行了研究。Berdasarkan标准引物dan探针untuk digunakan dalam rRT-PCR yitu suhu退火,tidak adanya pembentukan结构sekunder, % GC含量serta检测限,uji多重rRT-PCR yang dikembangkan pagada penelitian ini mampu mendeteksi DNA sintis RSV-A和RSV-B。kes脉冲an:多重rRT-PCR登根和孟古那坎引物和探针分离RSV-A和RSV-B,分离RSV-A和RSV-B,分离RSV-A和RSV-B,分离RSV-B。多路,实时RT-PCR, RSV-A, RSV-B
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引用次数: 0
Priority setting in responding crisis: a hospital leaders’ perspective at the early stage of COVID-19 pandemic 应对危机的优先级设置:新冠肺炎大流行早期医院领导的观点
Pub Date : 2021-12-16 DOI: 10.22435/hsji.v12i2.5295
A. Dewanto, Yudi Setyawan, V. Wardhani
Background: The COVID-19 pandemic hit Indonesia when hospitals were striving to adjust to a changing environment after a new health insurance system implementation, a government’s effort to achieve Universal Health Coverage. As a result, the pandemic forced hospitals to exploit their resources. Due to limited resources, setting accurate priorities is highly important to secure hospital operations and maintain its track towards the expected goals. This study aims to explore how deep the crisis impacts hospitals and how hospital leaders in Indonesia set their priorities in responding to the impact of this pandemic. Methods: This study used a descriptive and analytical approach. Data were collected through an online survey from hospital leaders and several documentary sources. Results: The results show that almost all hospital directors consider patient visits and hospital finance the most significant impacts of the COVID-19 pandemic. However, government hospital directors emphasize different areas compared to non-government hospital directors; the former sets their priorities on the hospital’s human resources, quality of service, and operations, while the latter focuses on the impact of patient visits and hospital finance. Conclusion: Although directors of government and non-governmental hospitals have a different emphasis, their priority is the same, maintaining hospital sustainability to provide quality services to people. Keywords:  COVID-19 pandemic, hospital leaders’ perspective, impacts, Indonesia, priority setting   Abstrak Latar belakang: Pandemi COVID-19 melanda Indonesia ketika rumah sakit berusaha menyesuaikan diri dengan lingkungan yang berubah setelah penerapan sistem jaminan kesehatan baru sebagai upaya pemerintah untuk mencapai Universal Health Coverage. Akibatnya, pandemi memaksa rumah sakit untuk mengeksploitasi sumber daya mereka. Sumber daya yang terbatas membuat penetapan prioritas yang akurat menjadi sangat penting untuk menjamin keberlangsungan operasional rumah sakit dan memastikan rumah sakit bergerak menuju tujuan yang diharapkan. Penelitian ini bertujuan untuk mengeksplorasi seberapa dalam dampak krisis ini terhadap rumah sakit dan bagaimana pemimpin rumah sakit di Indonesia menetapkan prioritasnya dalam merespon dampak pandemi ini. Metode: Penelitian ini menggunakan pendekatan deskriptif dan analitik. Data dikumpulkan melalui survei online dari pimpinan rumah sakit dan beberapa sumber dokumenter. Hasil: Hasil penelitian menunjukkan bahwa hampir semua direktur rumah sakit menganggap kunjungan pasien dan pembiayaan rumah sakit mendapat dampak paling signifikan dari pandemi COVID-19. Namun, direktur rumah sakit pemerintah menekankan bidang yang berbeda dibandingkan dengan direktur rumah sakit non-pemerintah. Direktur rumah sakit pemerintah menetapkan prioritas mereka pada sumber daya manusia rumah sakit, kualitas layanan, dan operasi, sedangkan direktur rumah sakit non-pemerintah fokus pada dampak kunjungan pasien d
背景:新冠肺炎疫情袭击了印度尼西亚,当时医院正在努力适应新的健康保险制度实施后不断变化的环境,这是政府为实现全民健康覆盖所做的努力。因此,新冠疫情迫使医院利用其资源。由于资源有限,制定准确的优先事项对于确保医院运营并保持其朝着预期目标发展至关重要。这项研究旨在探讨这场危机对医院的影响有多深,以及印尼的医院领导如何制定应对这场疫情影响的优先事项。方法:本研究采用描述性和分析性方法。数据是通过一项来自医院领导和一些文献来源的在线调查收集的。结果:结果显示,几乎所有医院院长都认为,新冠肺炎大流行对患者就诊和医院财务的影响最为显著。然而,与非政府医院院长相比,政府医院院长强调的领域不同;前者将重点放在医院的人力资源、服务质量和运营上,而后者则关注患者就诊和医院财务的影响。结论:尽管政府和非政府医院的院长有不同的侧重点,但他们的首要任务是相同的,即保持医院的可持续性,为人们提供优质服务。关键词:因此,流行病迫使医院利用其资源。有限的资源使得医院的精确优先级对于确保医院的运营连续性和确保医院朝着预期目标前进非常重要。这项研究旨在探讨这场危机对医院的影响,以及印尼医院院长如何制定应对这场疫情影响的优先事项。方法:本研究采用描述性和分析性方法。医院院长和一些文献来源通过在线调查收集的数据。结果:研究表明,几乎所有医院院长都认为患者就诊和医院资金对新冠肺炎大流行的影响最为显著。然而,与非政府医院院长相比,政府医院院长强调了不同的领域。政府医院院长将医院的人力资源、服务质量和运营列为优先事项,而非政府医院院长则将重点放在患者就诊和医院财务的影响上。结论:尽管政府医院院长和非政府医院院长的侧重点不同,但他们的首要任务是保持医院成功地为公众提供优质服务。关键词:新冠肺炎大流行,医院领导视角,影响,印度尼西亚,优先事项设置。
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引用次数: 0
The importance of hospital re-accreditation: improving the timeliness of laboratory critical value reporting 医院再认证的重要性:提高实验室临界值报告的及时性
Pub Date : 2021-12-16 DOI: 10.22435/hsji.v12i2.3315
Wahyu Febrianto, Menis Rahmawati, I. Sastrawan, T. Hariyanti
Background: Patient safety is the main issue in healthcare services nowadays. Delaying to inform the critical value of laboratory results is a significant source of harm for the patient. The aim of this study is to compare the timeliness of laboratory critical value reporting before and after re-accreditation as one of the service quality indicators in Hospital X. Methods: This study was done by using observational cross-sectional in Hospital X on January - February 2020 with total sampling method of critical value reporting to the responsible clinician that originated from Intensive Care Unit (ICU), Verlos Kamer (VK), and inpatient ward (IW) 1-6 from January-December 2019. The timeliness of reporting was counted since the laboratory result was obtained until received by the responsible clinician within £ 30 minutes and categorized as "On time" or "Late". Results: During 2019, there were 816 reporting which has been done before re-accreditation (511) and after re-accreditation (305) with 17 kinds of tests. The most reported test was platelet with 349 (before re-accreditation) and 101 (after re-accreditation), whilst SGOT/SGPT and albumin were the fewest one. The lowest timeliness of reporting percentage was 76,00% (February), whilst the highest was 98,48% (November). The timeliness of reporting's percentage was 84,34% (before re-accreditation) and 94,43% (after re-accreditation). The statistical analysis result revealed Pearson Chi-Square correlation was 18,535 with significance 0,000 and 3,145 odds ratio which shows that re-accreditation could significantly increase the timeliness of critical value reporting three times. Conclusion: This result showed that re-accreditation could affect the timeliness of laboratory critical value reporting to the responsible clinicians. Keywords: re-accreditation, critical value, laboratory, patient safety, hospital   Abstrak Latar belakang: Keselamatan pasien merupakan isu utama dalam pelayanan kesehatan. Tertundanya komunikasi hasil nilai kritis laboratorium merupakan sumber bahaya yang signifikan terhadap pasien. Penelitian ini bertujuan untuk membandingkan ketepatan waktu pelaporan nilai kritis laboratorium sebelum dan setelah reakreditasi sebagai salah satu indikator mutu di RS X. Metode: Penelitian dilakukan dengan cara observasional dengan metode cross sectional di RS X pada Januari - Februari 2020 dengan total sampling laporan nilai kritis kepada Dokter Penanggung Jawab Pasien (DPJP) yang berasal dari ruang Intensive Care Unit (ICU), Verlos Kamer (VK), dan ruang rawat inap 1 – 6 sejak Januari – Desember 2019. Ketepatan waktu pelaporan dihitung sejak hasil pemeriksaan didapatkan hingga diterima oleh DPJP dalam waktu £ 30 menit dan dinyatakan sebagai "Tepat Waktu" atau "Terlambat". Hasil: Selama tahun 2019, terdapat 816 pelaporan yang dilakukan sebelum akreditasi (511) dan setelahnya (305) dengan 17 jenis pemeriksaan. Pemeriksaan trombosit menjadi yang paling banyak dilaporkan yaitu 349 (sebelum ak
背景:患者安全是当今医疗服务中的主要问题。延迟告知实验室结果的临界值是对患者造成伤害的重要来源。本研究的目的是比较X医院作为服务质量指标之一的实验室临界值报告在重新认证前后的及时性。方法:本研究于2020年1月至2月在X医院使用观察性横断面进行,采用临界值总抽样法向2019年1月12月至12月来自重症监护室(ICU)、Verlos Kamer(VK)和住院病房(IW)1-6的负责临床医生报告。报告的及时性从获得实验室结果开始计算,直到责任临床医生在30分钟内收到,并被归类为“准时”或“迟到”。结果:2019年,共有816份报告,在重新认证之前(511份)和重新认证之后(305份)进行了17种类型的测试。报告最多的检测是血小板,349次(在重新认证之前)和101次(在再次认证之后),而SGOT/SGPT和白蛋白是最少的。报告及时性百分比最低的是7600%(2月),而最高的是98,48%(11月)。报告的及时性百分比为84,34%(重新认证前)和94,43%(重新认证后)。统计分析结果显示,Pearson Chi Square相关性为18535,显著性为0000,优势比为3145。这表明重新认证可以显著提高临界值报告的及时性三倍。结论:这一结果表明,重新认证可能会影响向负责任的临床医生报告实验室临界值的及时性。关键词:再鉴定、临界值、实验室、患者安全、医院事实证明,实验室临界值的交流对患者来说是一个重要的危险来源。本研究的目的是比较实验室临界值报告作为RS X的核心指标之一重新计入之前和之后的准确性。方法:该研究于2020年1-2月在RS X中采用横断面方法进行,自2019年1-12月以来,对重症监护室(ICU)、Verlos Kamer(VK)和1-6家医院的患者反应医生(DPJP)的临界值报告进行了总抽样。报告的速度根据DPJP在30分钟内接受的检查结果计算,并指定为“准确时间”或“延迟”。结果:2019年,在认证前(511)和认证后(305)共进行了816次报告,共进行了17种类型的检查。最常报告的血栓形成为349例(认证前)和101例(认证后),而SGOT/SGPT和白蛋白最低。报告准确率最低为76.00%(2月),最高为98.48%(11月)。报告时间的准确率分别为84.34%(认证前)和94.43%(认证后)。统计分析结果显示,皮尔逊-卡方相关性为18535,显著性为0000,奇数比为3145,这表明重新认证可以将临界值报告准确性提高三倍的概率。结论:这表明重新认证会影响向DPJP报告关键实验室值的准确性。关键词:再认证,临界值,实验室,患者安全,医院。
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引用次数: 1
Spatial variation of tuberculosis risk in Indonesia 2010-2019 2010-2019年印度尼西亚结核病风险的空间变化
Pub Date : 2021-12-16 DOI: 10.22435/hsji.v12i2.5467
Tities Puspita, A. Suryatma, O. S. Simarmata, G. Veridona, Heny Lestary, Athena Athena, I. Pambudi, S. Sulistyo, T. Pakasi
Background: As the second-highest country in tuberculosis (TB) cases globally, Indonesia has experienced an increasing trend of notification rate in the last ten years; however, the 34 provinces may have different risks. This study aims to examine TB risk variation across Indonesia in 2010-2019. Methods: A descriptive analysis was conducted on TB routine data of 2010-2019 from the Ministry of Health. Cases included all types of TB patients. Total cases, incidence rate (IR), and standardized morbidity ratio (SMR) were calculated for each province and national level during the period. Distributions of IRs and SMRs were displayed on maps. Results: During 2010-2019, 3,866,447 TB cases occurred in Indonesia, and the national IR was 1,523 per 100,000 populations. The highest proportion of cases and IR were in West Java (20.6%, 314 per 100,000); while the lowest was in North Kalimantan (0.2%, 3 per 100,000). Higher risks of TB occurred in DKI Jakarta (SMR 1.9), Papua (1.7), North Sulawesi (1.7), Maluku (1.5) and West Papua (1.5) among others. The smallest SMRs were found in Bali and Yogyakarta (0.5). Conclusion: TB risk varied across Indonesia in 2010-2019, with a higher risk in DKI Jakarta and several provinces in eastern Indonesia. Given the underreporting nature of routine data, validation is required when using the finding of this study in the local-level intervention. Keywords: tuberculosis, TB, standardized morbidity ratio, spatial variation, risk   Abstrak Latar belakang: Sebagai negara dengan jumlah kasus tuberkulosis (TB) terbesar kedua di dunia, Indonesia menunjukkan tren peningkatan notification rate di sepuluh tahun terakhir. Akan tetapi, risiko TB di 34 provinsi bisa saja berbeda-beda. Artikel ini bertujuan mengkaji variasi risiko TB di Indonesia pada tahun 2010-2019. Metode: Data rutin TB tahun 2010-2019 dari Kementerian Kesehatan dianalisis secara deskriptif. Kasus TB didefinisikan sebagai semua tipe pasien TB. Total jumlah kasus, incidence rate (IR), dan standardized morbidity ratio (SMR) dihitung untuk tiap provinsi dan tingkat nasional selama periode tersebut. Sebaran IR dan SMR diplot di atas peta. Hasil: Selama 2010-2019, terdapat 3.866.447 kasus TB dan IR nasional 1.523 per 100.000 populasi. Proporsi kasus dan IR terbesar ada di Jawa Barat (20,6%, 314 per 100.000) dan terkecil di Kalimantan Utara (0,2%, 3 per 100.000). Risiko TB lebih tinggi di antaranya terjadi di DKI Jakarta (SMR 1,9), Papua (1,7), Sulawesi Utara (1,7), Maluku (1,5) dan Papua Barat (1,5). Standardized Morbidity Ratio terendah ditemukan di Bali dan Yogyakarta (0,5). Kesimpulan: Dapat disimpulkan bahwa risiko TB beragam di seluruh Indonesia selama 2010-2019, di mana DKI Jakarta dan beberapa provinsi di timur Indonesia memiliki risiko lebih tinggi. Mengingat adanya kurang lapor dalam data rutin, validasi diperlukan jika menggunakan temuan studi ini dalam intervensi di tingkat lokal. Kata kunci: tuberkulosis, TB, standardized morbidity ratio, variasi spasia
背景:作为全球结核病病例第二高的国家,印度尼西亚在过去十年中的通知率呈上升趋势;然而,这34个省份可能存在不同的风险。本研究旨在调查2010-2019年印尼各地结核病风险的变化。方法:对卫生部2010-2019年结核病常规数据进行描述性分析。病例包括所有类型的结核病患者。在此期间,计算了各省和全国的总病例数、发病率(IR)和标准化发病率(SMR)。IR和SMR的分布显示在地图上。结果:2010-2019年期间,印度尼西亚发生了3866447例结核病病例,全国IR为每100000人口1523例。西爪哇的病例和IR比例最高(20.6%,每100000人中有314人);北加里曼丹最低(0.2%,十万分之三)。DKI雅加达(SMR 1.9)、巴布亚(1.7)、北苏拉威西(1.7),马鲁古(1.5)和西巴布亚(1.5)等地的结核病风险较高。巴厘岛和日惹的SMR最小(0.5)。结论:2010-2019年,印尼各地的结核病风险各不相同,DKI雅加达和印尼东部几个省的风险更高。鉴于常规数据的漏报性质,在地方层面的干预中使用本研究的发现时,需要进行UNK]验证。关键词:结核病、结核病、标准化发病率、空间变异、风险背景摘要:作为世界上结核病病例第二大的国家,印度尼西亚在过去十年中的通报率呈上升趋势。然而,34个省份的结核病风险可能有所不同。本文旨在研究2010-2019年印尼结核病风险的变化。方法:对卫生部2010-2019年结核病常规数据进行描述性分析。结核病病例被定义为所有类型的结核病患者。在此期间,每个省和国家层面计算的病例总数、发病率(IR)和标准化发病率(SMR)。IR和SMR广播被张贴在地图上。结果:2010-2019年期间,每100000人口中有3866447例结核病病例,全国IR为1523例。病例和IR的比例最大的是西岸(20.6%,每100000人中有314人),最低的是北加利福尼亚州(0.2%,每100000万人中有3人)。巴厘岛和日惹的标准化发病率最低(0.5)。结论:可以得出结论,2010-2019年期间,印尼各地的结核病风险各不相同,雅加达DKI和印度尼西亚东部的几个省的结核病风险较高。鉴于常规数据中缺乏报告,如果将这项研究结果用于地方层面的干预,则需要进行验证。关键词:结核病、结核病、标准化发病率、空间变异、风险
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引用次数: 4
Factors associated with measles antibody titers in children aged 12-36 months in Indonesia: an analysis of National Health Research 2013 印度尼西亚12-36个月儿童麻疹抗体滴度的相关因素:2013年国家卫生研究的分析
Pub Date : 2021-12-16 DOI: 10.22435/hsji.v12i2.5356
N. Aryastami, P. P. Arfines, V. Setiawaty, S. Isfandari
Background: The immunization program in Indonesia has been implemented since 1956 started to eradicate smallpox and expanded until 1980, including Measles. The timely and complete implementation of basic immunization is the main strategy to protect the population, including outbreak prevention. The purpose of this study is to determine the level immunity of Measles antibody as the outcome of completed basic immunization and its contributors in children aged 12-36 months. Methods: This study is a secondary data analysis of the Indonesia Basic Health Survey (RISKESDAS) 2013. The analysis was carried out on a serological sample of the antibody titer of children aged 12-36 months, totaling 229 samples. The sample inclusion criteria were children who had complete sociodemographics data, basic immunization records and Measles antibody titer data. Measles examination was carried out using the Enzyme-Linked Immunosorbent Assay (ELISA) method.   Results: Incomplete immunization, being a boy, and lack of cleanliness in the family room were significantly associated with lower measles antibody levels in children. Having each variable controlled, completeness of immunization (OR=1,99; p=0.018; 95% CI=1.124-3.544) and gender of boy (OR=2.0; p=0.016; 95% CI=1.137-3.515) remain as significant variables for antibody’s titer. Conclusion: The completeness of immunization has a significant association towards titer antibody of Measles in children. Immunization completeness is an actual effort to reach herd immunity in children and to prevent measles outbreak in the community. Adequate health promotion is needed to change people's behavior to believe in the safety and importance of implementing complete basic immunization for children even in pandemic conditions. Keywords: antibody titer, immunization, children aged 12-36 months, Indonesia, measles   Abstrak Latar belakang: Program imunisasi di Indonesia telah dilaksanakan sejak tahun 1956 yang dimulai dengan pemberantasan cacar yang diperluas hingga tahun 1980, termasuk campak. Pelaksanaan imunisasi dasar yang tepat waktu dan lengkap merupakan strategi utama untuk perlindungan penduduk, termasuk pencegahan Kejadian Luar Biasa (KLB). Tujuan dari penelitian ini untuk mengetahui tingkatan kekebalan antibodi Campak sebagai hasil dari kelengkapan imunisasi dasar dan faktor yang berkontribusi pada anak usia 12-36 bulan. Metode: Penelitian ini merupakan analisis data sekunder Riset Kesehatan Dasar Indonesia (RISKESDAS) 2013. Analisis dilakukan pada sampel serologi titer antibodi anak usia 12-36 bulan yang berjumlah 229 sampel. Kriteria inklusi sampel adalah anak yang memiliki data sosiodemografi lengkap, catatan imunisasi dasar dan data titer antibodi Campak. Pemeriksaan campak dilakukan dengan metode Enzyme-Linked Immunosorbent Assay (ELISA). Hasil: Imunisasi yang tidak lengkap, berjenis kelamin laki-laki, dan kurangnya kebersihan di ruang keluarga berhubungan bermakna dengan rendahnya tingkat antibodi campak pad
背景:印度尼西亚的免疫接种计划自1956年开始实施,开始根除天花,并扩大到1980年,包括麻疹。及时全面实施基本免疫是保护人口的主要战略,包括预防疫情爆发。本研究的目的是确定作为完成基础免疫的结果的麻疹抗体的免疫水平及其在12-36个月儿童中的贡献者。方法:本研究是对2013年印度尼西亚基本健康调查(RISKESDAS)的二次数据分析。对12-36个月儿童的抗体滴度血清学样本进行分析,共229份样本。样本纳入标准为具有完整社会人口统计数据、基本免疫记录和麻疹抗体滴度数据的儿童。麻疹检测采用酶联免疫吸附试验(ELISA)方法。【UNK】结果:未完成免疫接种、身为男孩以及家庭房间缺乏清洁与儿童麻疹抗体水平较低显著相关。控制每个变量后,免疫的完整性(OR=1.99;p=0.018;95%CI=1.24-3.544)和男孩的性别(OR=2.0;p=0.016;95%CI=1.137-3.515)仍然是抗体滴度的重要变量。结论:免疫接种的完整性与儿童麻疹抗体滴度有显著关系。免疫完整性是实现儿童群体免疫和预防社区麻疹爆发的实际努力。需要充分的健康宣传,以改变人们的行为,使他们相信即使在疫情条件下,为儿童实施完全基本免疫的安全性和重要性。关键词:抗体滴度,免疫接种,12-36个月大的儿童,印度尼西亚,麻疹[UNK]背景Abstrak:印度尼西亚的免疫接种计划自1956年开始实施,从消灭蠕虫开始,一直延长到1980年,包括运动。及时全面实施基本免疫接种是保护人口的关键战略,包括预防特殊事件(KLB)。本研究的目的是确定12-36个月大儿童因基础免疫失败而放弃的抗体免疫水平和促成因素。方法:本研究是对2013年印尼主要健康研究(RISK)的二次分析。对12-36个月儿童的抗体滴度血清学样本进行了分析,共有229份样本。样本纳入标准为具有完整社会人口统计数据、基本免疫记录和抗体滴度数据的儿童。使用酶联免疫吸附测定(ELISA)方法进行喉咙测试。结果:不完全的免疫接种、男性类型和家庭房间缺乏清洁意味着向儿童投掷的抗体水平较低。在每个对照变量之后,免疫抑制(OR=1.99;p=0.018;95%CI=1.24-3.544)和男性类型(OR=2.0;p=0.016;95%CI=1.137-3.515)是与抗体滴度保持显著相关的变量。结论:免疫装置与儿童血清抗体滴度有一定关系。免疫工具是接触儿童免疫群体和防止社会疫情爆发的真正努力。需要充分的健康宣传来改变社会行为,以便相信儿童的安全性和充分免疫的重要性,即使在疫情条件下也是如此。关键词:抗体滴度,免疫,12-36个月大,印度尼西亚,扔掉
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引用次数: 0
Stigma during COVID-19 pandemic among healthcare workers in greater Jakarta metropolitan area: a cross-sectional online study 大雅加达大都市区卫生保健工作者在COVID-19大流行期间的耻辱感:一项横断面在线研究
Pub Date : 2021-07-19 DOI: 10.22435/hsji.v12i1.4754
Ika Saptarini, N. Novianti, Anissa Rizkianti, Iram Barida Maisya, S. Suparmi, G. Veridona, Ning Sulistiyowati, Sudikno Sudikno
Background: COVID-19, which started in Wuhan, has become a global pandemic leading to a new global risk to human health. Lack of information or misinformation about COVID-19 can lead to stigmatization, including for health workers. This study aims to determine the stigmatization among health workers during the COVID-19 pandemic within the Greater Jakarta Metropolitan Area. Methods: This study was a cross-sectional study conducted online using Google Forms in the Jabodetabek area. The questionnaire’s link was distributed through social media, including Whatsapp, Facebook, Twitter, and Instagram. The study sample is health workers who live in Jabodetabek and carry out health practices. Stigma is measured using four dimensions: personalized stigma, disclosure concerns, public attitudes, and negative self-image. Result: The negative self-image dimension is the dimension most felt by health workers. More than half of health workers agreed that during the COVID-19 pandemic, they put their families at risk because of their status as health workers. The stigma of health workers who work in hospitals is higher than that of non-hospital health workers, such as health centers, clinics, and laboratories. Conclusion: There was any stigmatization among healthcare workers in Greater Jakarta Metropolitan Area. Stigmatization was higher among healthcare workers who work in hospitals compared to those who work in non-hospitals. Some efforts should be made to reduce stigmatization among health workers, such as provide correct information to the public, equip health personnel with adequate personal protective equipment, and give incentives periodically to the health workers. Keywords: Stigma, COVID-19, healthcare workers, Greater Jakarta Metropolitan Area Abstrak Latar belakang: COVID-19 yang bermula dari Wuhan telah menjadi pandemi global yang mengancam kesehatan umat manusia. Kurangnya informasi atau informasi yang salah mengenai COVID-19 dapat menyebabkan adanya stigmatisasi termasuk terhadap tenaga kesehatan. Penelitian ini menilai adanya stigmatisasi terhadap tenaga kesehatan selama pandemi COVID-19 di wilayah Jabodetabek. Metode: Penelitian ini merupakan penelitian potong lintang dan dilakukan secara daring menggunakan Google Form di wilayah Jabodetabek. Tautan pengisian kuesioner disebarkan melalui media sosial seperti Whatsapp, Facebook, Twitter dan Instagram. Sampel studi adalah tenaga kesehatan yang tinggal di Jabodetabek dan melakukan praktik kesehatan. Stigma diukur menggunakan empat dimensi yaitu personized stigma, disclosure concerns, concerns about public attitudes dan negative self-image. Hasil: Dimensi negative self-image merupakan dimensi yang paling dirasakan oleh tenaga kesehatan. Lebih dari separuh tenaga kesehatan setuju bahwa selama pandemi COVID-19 mereka membahayakan keluarga mereka karena status mereka sebagai tenaga kesehatan. Stigma pada tenaga kesehatan yang bekerja di rumah sakit lebih tinggi disbanding tenaga kesehatan
背景:始于武汉的新冠肺炎已成为全球大流行,给人类健康带来新的全球风险。缺乏关于新冠肺炎的信息或错误信息可能导致污名化,包括对卫生工作者的污名化。本研究旨在确定新冠肺炎大流行期间大雅加达都市区卫生工作者的污名化。方法:本研究是一项在Jabodetabek地区使用谷歌表单在线进行的横断面研究。调查问卷的链接通过社交媒体发布,包括Whatsapp、Facebook、Twitter和Instagram。研究样本是居住在Jabodetabek并从事卫生实践的卫生工作者。污名是通过四个维度来衡量的:个性化污名、披露问题、公众态度和负面自我形象。结果:消极的自我形象维度是卫生工作者感受最深的维度。超过一半的卫生工作者同意,在新冠肺炎大流行期间,由于他们的卫生工作者身份,他们将家人置于危险之中。在医院工作的卫生工作者的耻辱感高于非医院卫生工作者,如卫生中心、诊所和实验室。结论:在大雅加达都会区的医护人员中存在任何污名化现象。与非医院工作人员相比,在医院工作的医护人员的污名化程度更高。应努力减少卫生工作者的污名化,例如向公众提供正确的信息,为卫生人员配备足够的个人防护设备,并定期向卫生工作者提供奖励。关键词:耻辱,新冠肺炎,医护人员,大雅加达都市区Abstrak背景:始于武汉的新冠肺炎已成为威胁人类健康的全球大流行。关于新冠肺炎的信息较少或不正确可能导致包括健康在内的污名化。这项研究评估了新冠肺炎大流行期间在贾博德塔贝克对健康的污名化。方法:本研究是一项跨领域的研究,在日本免费使用谷歌表单进行。聚合填充链接通过Whatsapp、Facebook、Twitter和Instagram等社交媒体传播。研究样本是生活在Jabodetabek并进行健康实践的健康能量。污名是通过四个维度来衡量的:个性化污名、披露担忧、对公众态度的担忧和负面的自我形象。结果:负面自我形象维度是健康感受最深的维度。超过一半的卫生部队同意,在新冠肺炎大流行期间,他们因健康状况而危及家人。在医院工作的医疗保健的耻辱感高于在图书馆、诊所和实验室等医院以外的医疗保健。结论:工作场所存在对卫生官员的污名化。在医院工作的医护人员中,污名化程度高于不在医院工作人员。需要做出一些努力来减少医疗保健专业人员的污名化,例如向公众提供正确的信息,用适当的防护工具补充健康,并定期为他们提供激励。关键词:[UNK][UNK][UNK]耻辱,新冠肺炎,健康,就业
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引用次数: 6
First experience of using favipiravir in the first healthcare worker patient with moderate case of Coronavirus Disease 2019 (COVID-19) at Sulianti Saroso Infectious Disease Hospital, Jakarta, Indonesia: a case report 印度尼西亚雅加达Sulianti Saroso传染病医院第一例中度2019冠状病毒病(新冠肺炎)医护人员患者首次使用法匹拉韦的经验:病例报告
Pub Date : 2021-07-19 DOI: 10.22435/hsji.v12i1.4879
Pompini Agustina Sitompul, N. Mariana, A. Rusli
Background: During the early period of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic, there was no approved and definitive drug available for the treatment of COVID-19. Favipiravir, chloroquine, hydroxychloroquine was used for re-purposing drugs while their efficacy and safety remained a major concern for healthcare workers. Clinical trial to assess efficacy and safety were ongoing. Case presentation: We present here the case of a 38-year-old woman, the first case of a healthcare worker diagnosed with COVID-19 who had moderate type, including first experience treatment with favipiravir in Sulianti Saroso Infectious Disease Hospital, Jakarta, Indonesia. We present the clinical characteristics, chest X-ray, clinical laboratory profiles, the treatment process with favipiravir and hydroxychloroquine as well as the clinical outcome of moderate type COVID-19 patient. Conclusion: This case highlights that considering the use of emergency intervention outside of clinical trial in the COVID-19 population, the informed patient consent has been given and the use of emergency intervention was monitored. Keywords: COVID-19, favipiravir, medical worker, case report, Jakarta   Abstrak Latar belakang: Periode awal pandemi Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), belum terdapat obat yang disetujui dan pasti tersedia untuk pengobatan COVID-19. Favipiravir, chloroquine, hydroxychloroquine digunakan sebagai obat dengan indikasi baru yang sementara efektifitas dan keamanannya menjadi perhatian para petugas medis. Penyajian kasus: Disini kami melaporkan kasus wanita umur 38 tahun, merupakan kasus pertama seorang tenaga kesehatan Rumah Sakit terdiagnosis Coronavirus Disease 2019 (COVID-19) dengan penggunaan terapi favipiravir untuk pertama kalinya di Rumah Sakit Pusat Infeksi Sulianti Saroso, Jakarta, Indonesia. Berikut ini kami gambarkan karakteristik klinis, hasil foto thorak, profil laboratorium dan proses terapi menggunakan favipiravir and hidroxychloroquine serta hasil akhir pada kasus COVID-19 derajat sedang. Kesimpulan: Kasus ini menggaribawahi bahwa pertimbangan penggunaan kegawatdaruratan obat antivirus diluar uji klinis pada populasi pasien COVID-19, pasien telah memberikan persetujuan dan penggunaan obat-obat tersebut dimonitor. Kata kunci: Covid-19, favipiravir, tenaga kesehatan, laporan kasus, Jakarta
背景:在严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)大流行的早期,没有批准和确定的药物可用于治疗COVID-19。法匹拉韦、氯喹和羟氯喹被用于重新利用药物,而它们的有效性和安全性仍然是卫生保健工作者关注的主要问题。评估疗效和安全性的临床试验正在进行中。病例介绍:我们在这里介绍一名38岁妇女的病例,这是第一例被诊断为COVID-19的中度型卫生保健工作者,包括在印度尼西亚雅加达Sulianti Saroso传染病医院首次接受法匹拉韦治疗。介绍1例中重度COVID-19患者的临床特点、胸片、临床实验室资料、法匹拉韦联合羟氯喹治疗过程及临床转归。结论:本病例强调,考虑到COVID-19人群在临床试验之外使用紧急干预措施,已获得患者知情同意并监测紧急干预措施的使用情况。关键词:COVID-19,法匹拉韦,医务工作者,病例报告,雅加达摘要:周期性大流行的严重急性呼吸综合征冠状病毒2 (SARS-CoV-2), belum terdapat bata yang disetujui和pasti tersedia untuk pengobatan COVID-19。法匹拉韦、氯喹、羟氯喹的研究进展。Penyajian kasus: Disini kami melaporkan kasus wanita umur 38 tahun, merupakan kasus pertama seorang tenaga kesehatan Rumah Sakit诊断冠状病毒病2019 (COVID-19) dengan penggunaan terapi favipiravir untuk pertama kalinya di Rumah Sakit Pusat Infeksi Sulianti Saroso,印度尼西亚雅加达。Berikut ini kami gambarkan karakteristik klinis, hasil foto thorak,概况实验室研究了terapi menggunakan favipiravir和羟氯喹seril - hroxychloroquine,用于治疗2019冠状病毒病(COVID-19)。kespulan: Kasus ini menggaribawahi bahwa pertimbangan penggunaan kegawatdaruratan抗禽流感病毒的稀松剂uji klinis pada populasen COVID-19, psien telah成员kan persetujuan dan penggunaan obat-obat - tersebut dimonitor。Kata kunci: Covid-19, favipiravir, tenaga kesehatan, laporan kasus,雅加达
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引用次数: 0
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Health Science Journal of Indonesia
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