Pub Date : 2022-01-10DOI: 10.22435/hsji.v12i2.4938
Desta Ayu Cahya Rosyida, Nina Nikmah, Khoiriyah Noviastuti
Background: Postpartum blues is common in postpartum Mother with more prone to crying, more anxious, often unstable and more emotional than usual. Zinc supplementation is one of the methods needed for postpartum blues conditions. Kidney bean (phaseolus vulgaris) extract has the highest zinc content. This study aimed to examine the effect of intake kidney bean extract (phaseolus vulgaris) as a zinc source as management mother with Postpartum Blues Methods: Quantitative study with an experimental study design (Quasi Experiment Design) with a Pre and Post-test Control Group Design. The instrument used to measure the mood of a mother after childbirth was EPDS (Edinburgh Post-Partum Depression Scale). The total sample was 68 mothers who experienced postpartum blues in Ngerandu Ponorogo primary health care. The Mann-Whitney was used to analyse and find out the difference in mood improvement before and after the intervention in the experimental group and the control group. Results: The results showed that there was a statistically significant difference in mood levels of mothers with postpartum blues before and after intervention (p value of 0.001 (<0.005). This result indicated that intake of kidney bean (Phaseolus vulgaris) extract had an effect on the mood level of mothers with postpartum blue. Conclusion: Intake of kidney bean (phaseolus vulgaris) extract on the incidence of postpartum blues possibly improvement mood in the experimental group after the treatment for 1 month. Keywords: kidney bean (phaseolus vulgaris) extract, postpartum blues, postpartum mother Abstrak Latar belakang: Postpartum blues umum terjadi pada ibu postpartum dengan tanda sering menangis, khawatir yang berlebihan, emosional yang tidak stabil. Suplementasi zinc merupakan salah satu metode yang dibutuhkan untuk kondisi postpartum blues. Ektrak kacang merah (phaseolus vulgaris) memiliki sumber nutrisi zinc yang tinggi, Penelitian ini bertujuan untuk menguji efek konsumsi ekstrak kacang merah (phaseolus vulgaris) sebagai sumber zinc sebagai manajemen ibu dengan postpartum blues Metode: Penelitian kuantitatif dengan design Quasi Experiment pre dan post control grup. Instrumen pengukur mood ibu setelah melahirkan adalah EPDS (Edinburgh Post-Partum Depression Scale). Total Sampel 68 ibu yang mengalami postpartum blues di Puskesmas Ngerandu Ponorogo. Analisis statistik menggunakan Mann-Whitney untuk menemukan perbedaan perubahan mood ibu postpartum blues sebelum dan sesudah dilakukan intervensi pada grup intervensi dan kontrol. Hasil: Hasil menunjukkan bahwa terdapat perbedaan signifikan tingkat mood ibu dengan postpartum blues sebelum dan sesudah dilakukan intervensi (p : 0,001 (<0,005). Hasil mengindikasikan bahwa konsumsi ekstrak kacang merah (phaseolus vulgaris) memiliki efek pada tingkat mood ibu yang sedang mengalami postpartum blues. Kesimpulan: Konsumsi ekstrak kacang merah (phaseolus vulgaris) pada ibu postpartum blues memungkinkan untuk perubahan mood pada grup
{"title":"Intake of kidney bean (phaseolus vulgaris) extract as postpartum blues management","authors":"Desta Ayu Cahya Rosyida, Nina Nikmah, Khoiriyah Noviastuti","doi":"10.22435/hsji.v12i2.4938","DOIUrl":"https://doi.org/10.22435/hsji.v12i2.4938","url":null,"abstract":"Background: Postpartum blues is common in postpartum Mother with more prone to crying, more anxious, often unstable and more emotional than usual. Zinc supplementation is one of the methods needed for postpartum blues conditions. Kidney bean (phaseolus vulgaris) extract has the highest zinc content. This study aimed to examine the effect of intake kidney bean extract (phaseolus vulgaris) as a zinc source as management mother with Postpartum Blues \u0000Methods: Quantitative study with an experimental study design (Quasi Experiment Design) with a Pre and Post-test Control Group Design. The instrument used to measure the mood of a mother after childbirth was EPDS (Edinburgh Post-Partum Depression Scale). The total sample was 68 mothers who experienced postpartum blues in Ngerandu Ponorogo primary health care. The Mann-Whitney was used to analyse and find out the difference in mood improvement before and after the intervention in the experimental group and the control group. \u0000Results: The results showed that there was a statistically significant difference in mood levels of mothers with postpartum blues before and after intervention (p value of 0.001 (<0.005). This result indicated that intake of kidney bean (Phaseolus vulgaris) extract had an effect on the mood level of mothers with postpartum blue. \u0000Conclusion: Intake of kidney bean (phaseolus vulgaris) extract on the incidence of postpartum blues possibly improvement mood in the experimental group after the treatment for 1 month. \u0000Keywords: kidney bean (phaseolus vulgaris) extract, postpartum blues, postpartum mother \u0000 \u0000Abstrak \u0000Latar belakang: Postpartum blues umum terjadi pada ibu postpartum dengan tanda sering menangis, khawatir yang berlebihan, emosional yang tidak stabil. Suplementasi zinc merupakan salah satu metode yang dibutuhkan untuk kondisi postpartum blues. Ektrak kacang merah (phaseolus vulgaris) memiliki sumber nutrisi zinc yang tinggi, Penelitian ini bertujuan untuk menguji efek konsumsi ekstrak kacang merah (phaseolus vulgaris) sebagai sumber zinc sebagai manajemen ibu dengan postpartum blues \u0000Metode: Penelitian kuantitatif dengan design Quasi Experiment pre dan post control grup. Instrumen pengukur mood ibu setelah melahirkan adalah EPDS (Edinburgh Post-Partum Depression Scale). Total Sampel 68 ibu yang mengalami postpartum blues di Puskesmas Ngerandu Ponorogo. Analisis statistik menggunakan Mann-Whitney untuk menemukan perbedaan perubahan mood ibu postpartum blues sebelum dan sesudah dilakukan intervensi pada grup intervensi dan kontrol. \u0000Hasil: Hasil menunjukkan bahwa terdapat perbedaan signifikan tingkat mood ibu dengan postpartum blues sebelum dan sesudah dilakukan intervensi (p : 0,001 (<0,005). Hasil mengindikasikan bahwa konsumsi ekstrak kacang merah (phaseolus vulgaris) memiliki efek pada tingkat mood ibu yang sedang mengalami postpartum blues. \u0000Kesimpulan: Konsumsi ekstrak kacang merah (phaseolus vulgaris) pada ibu postpartum blues memungkinkan untuk perubahan mood pada grup","PeriodicalId":30666,"journal":{"name":"Health Science Journal of Indonesia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46162814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-16DOI: 10.22435/hsji.v12i2.5243
Relawantria Harlianti, Trias Mahmudiono, D. Atmaka, S. Helmyati, Mira Dewi, C. T. Yuniar
Background: In Indonesia, the prevalence of smoking is increasing from year to year and can cause various health problems, such as sleep disorders and affect a person's nutritional status. So, in this study, the relationship between smoking duration, sleep disturbances, and nutritional status in men aged 26–45 years will be investigated using secondary data from the 2014 Indonesia Family Live Survey (IFLS). Methods: The 2014 secondary data from the fifth waves of the IFLS were used for analysis. All 5,379 data of men aged 26–45 years who provided anthropometric, smoking duration, and sleep disorders were included in the study. The Chi-Square test was used to examine the relationship between smoking duration, sleep disorders, and nutritional status in men aged 26 – 45 years. Furthermore, the Multinomial Logistics Regression test is carried out to determine the variables that have the strongest influence. Results: Based on the results of statistical tests conducted, it was found that the majority of respondents had a smoking duration of 11-20 years, of which 27.2% of respondents did not experience sleep disorders and 25.4% had sleep disorders. The nutritional status of respondents with a smoking duration of 11-20 years is normal as many as 35% of respondents and at least 0.5% of respondents have underweight nutritional status with smoking duration <5 years. Furthermore, the test results of the relationship between smoking duration and sleep disturbances obtained p-value = 0.03 and the relationship between smoking duration and nutritional status obtained p-value <0.01. Conclusion: Smoking duration was associated with sleep disorder and overweight nutritional status in men aged 26 – 45 years. Keywords: smoking duration, sleep disorder, nutritional status, tobacco use, sleeping sickness Abstrak Latar belakang: Di Indonesia, prevalensi merokok semakin meningkat dari tahun ke tahun dan dapat menyebabkan berbagai permasalahan kesehatan, seperti gangguan tidur serta mempengaruhi status gizi seseorang. Sehingga pada penelitian ini akan diteliti hubungan antara durasi merokok, gangguan tidur, dan status gizi pada pria berusia 26–45 tahun menggunakan data sekunder dari Indonesia Family Live Survey (IFLS) tahun 2014. Metode: Analisis dari data sekunder gelombang kelima IFLS tahun 2014. Semua 5.379 data pria berusia 26–45 tahun yang memiliki kelengkapan data antropometri, kebiasaan merokok, dan gangguan tidur diikutkan dalam penelitian. Uji Chi-Square digunakan untuk menguji hubungan antara durasi merokok, gangguan tidur, dan status gizi pada pria berusia 26 – 45 tahun. Selanjutnya uji Regresi Logistik Multinomial dilakukan untuk mengetahui variabel yang memiliki pengaruh paling kuat. Hasil: Berdasarkan hasil dari uji statistik yang dilakukan, didapatkan bahwa mayoritas responden memiliki durasi merokok selama 11-20 tahun, dimana sebanyak 27.2% responden tidak mengalami gangguan tidur dan 25.4% mengalami gangguan tidur. Status gizi paling banyak ya
背景:在印度尼西亚,吸烟的流行率逐年上升,并可能导致各种健康问题,如睡眠障碍和影响一个人的营养状况。因此,在本研究中,将使用2014年印度尼西亚家庭生活调查(IFLS)的二手数据调查26-45岁男性吸烟持续时间、睡眠障碍和营养状况之间的关系。方法:采用2014年IFLS第五波二次资料进行分析。5379名年龄在26-45岁之间的男性提供了人体测量、吸烟持续时间和睡眠障碍的数据都被纳入了研究。采用卡方检验检验26 - 45岁男性吸烟持续时间、睡眠障碍和营养状况之间的关系。此外,进行多项logistic回归检验,以确定影响最强的变量。结果:根据统计检验的结果,大多数受访者的吸烟时间为11-20年,其中27.2%的受访者没有睡眠障碍,25.4%的受访者有睡眠障碍。吸烟时间为11-20年的被调查者营养状况正常的比例高达35%,吸烟时间<5年的被调查者营养状况不足的比例至少为0.5%。吸烟持续时间与睡眠障碍关系的检验结果p值= 0.03,吸烟持续时间与营养状况关系的检验结果p值<0.01。结论:吸烟持续时间与26 ~ 45岁男性的睡眠障碍和超重营养状况有关。关键词:吸烟时间,睡眠障碍,营养状况,烟草使用,昏睡病。摘要:印度尼西亚,流行病学,流行病学,流行病学,流行病学,流行病学,流行病学,流行病学。sehinga pada penelitian ini akan diteliti hubungan antara durasi merokok, gangguan tidur, danstatus gizi pada pria berusia 26-45, tahun menggunakan数据收集于印度尼西亚家庭生活调查(IFLS), 2014年1月。方法:根据2014年中国国际地理信息系统(IFLS)的数据进行分析。[3] [1] [1] [1] [1] [1] [1] [1] [4] [1] [1] [4] [1] [4] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1]Uji Chi-Square digunakan untuk menguji hubungan antara durasi merokok, gangguan tidur, dan status gizi pada pria beria 26 - 45 tahun。[3][1][1][1][1][1][1][1][2][1][1]。Hasil: Berdasarkan Hasil dari uji statistics yang dilakukan, didapatkan bahwa mayoritas respondeniliki durasi merokok selama 11-20 tahun, dimana sebanyak 27.2% respondenak mengalami gangguan tidur和25.4% mengalami gangguan tidur。状态gizi paling banyak yang dimiliki oleh应答dengan durasi merokok selama 11-20 tahun adalah正常sebanyak 35%应答dengan paling sedikit sebanyak 0.5%应答memiliki状态gizi体重过轻dengan durasi merokok <5 tahun。Selanjutnya hasil uji hubungan antara durasi merokok dengan gangguan tidur didapatkan nilai p值=0.03但hubungan antara durasi merokok dengan status gizi didapatkan nilai p值<0.01。kespulan: Durasi merokok berhubungan dengan gangguan tidur dan status gizi超重帕达·拉基·拉基·乌苏亚26 - 45 tahun。Kata kunci: durasi merokok, gangguan tidur, status gizi, penggunaan tembakau, penyakit tidur
{"title":"The relationship of smoking duration, sleep disorders, and nutritional status of Indonesian adult men: data analysis of the 2014 Indonesian Family Life Surve","authors":"Relawantria Harlianti, Trias Mahmudiono, D. Atmaka, S. Helmyati, Mira Dewi, C. T. Yuniar","doi":"10.22435/hsji.v12i2.5243","DOIUrl":"https://doi.org/10.22435/hsji.v12i2.5243","url":null,"abstract":"Background: In Indonesia, the prevalence of smoking is increasing from year to year and can cause various health problems, such as sleep disorders and affect a person's nutritional status. So, in this study, the relationship between smoking duration, sleep disturbances, and nutritional status in men aged 26–45 years will be investigated using secondary data from the 2014 Indonesia Family Live Survey (IFLS). \u0000Methods: The 2014 secondary data from the fifth waves of the IFLS were used for analysis. All 5,379 data of men aged 26–45 years who provided anthropometric, smoking duration, and sleep disorders were included in the study. The Chi-Square test was used to examine the relationship between smoking duration, sleep disorders, and nutritional status in men aged 26 – 45 years. Furthermore, the Multinomial Logistics Regression test is carried out to determine the variables that have the strongest influence. \u0000Results: Based on the results of statistical tests conducted, it was found that the majority of respondents had a smoking duration of 11-20 years, of which 27.2% of respondents did not experience sleep disorders and 25.4% had sleep disorders. The nutritional status of respondents with a smoking duration of 11-20 years is normal as many as 35% of respondents and at least 0.5% of respondents have underweight nutritional status with smoking duration <5 years. Furthermore, the test results of the relationship between smoking duration and sleep disturbances obtained p-value = 0.03 and the relationship between smoking duration and nutritional status obtained p-value <0.01. \u0000Conclusion: Smoking duration was associated with sleep disorder and overweight nutritional status in men aged 26 – 45 years. \u0000Keywords: smoking duration, sleep disorder, nutritional status, tobacco use, sleeping sickness \u0000 \u0000Abstrak \u0000Latar belakang: Di Indonesia, prevalensi merokok semakin meningkat dari tahun ke tahun dan dapat menyebabkan berbagai permasalahan kesehatan, seperti gangguan tidur serta mempengaruhi status gizi seseorang. Sehingga pada penelitian ini akan diteliti hubungan antara durasi merokok, gangguan tidur, dan status gizi pada pria berusia 26–45 tahun menggunakan data sekunder dari Indonesia Family Live Survey (IFLS) tahun 2014. \u0000Metode: Analisis dari data sekunder gelombang kelima IFLS tahun 2014. Semua 5.379 data pria berusia 26–45 tahun yang memiliki kelengkapan data antropometri, kebiasaan merokok, dan gangguan tidur diikutkan dalam penelitian. Uji Chi-Square digunakan untuk menguji hubungan antara durasi merokok, gangguan tidur, dan status gizi pada pria berusia 26 – 45 tahun. Selanjutnya uji Regresi Logistik Multinomial dilakukan untuk mengetahui variabel yang memiliki pengaruh paling kuat. \u0000Hasil: Berdasarkan hasil dari uji statistik yang dilakukan, didapatkan bahwa mayoritas responden memiliki durasi merokok selama 11-20 tahun, dimana sebanyak 27.2% responden tidak mengalami gangguan tidur dan 25.4% mengalami gangguan tidur. Status gizi paling banyak ya","PeriodicalId":30666,"journal":{"name":"Health Science Journal of Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48176023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Patient with diabetes mellitus (DM) occurs chronic inflammation by characterized a decreased concentration of various cytokinin types. This causes changes in the body’s immunity so that can be easier in having an infection. One of the most important cytokines against infection is IFN-γ. This study aimed to determine IFN-γ concentration in DM and dyslipidemia patients. Metode: An amount of 234 people who received treatment at the health center in Banda Aceh in 2019 were included in this study. From each respondent, 5 ml of blood was taken to check fasting blood glucose, triglycerides, high-density lipoproteins (HDL), and interferon-gamma (IFN-γ). Test of fasting blood glucose, triglycerides, HDL was carried out using the colorimetric enzymatic method. The IFN-γ protein concentration was examined using the sandwich enzyme-linked immunosorbent assay (ELISA) technique. Result: IFN-γ concentration in the non-DM group was higher than in the DM group. There was a significant difference between the average IFN-γ concentration in the non-DM group compared with the DM group (p = 0.000). All DM patients had increased fasting blood glucose, most had hypertriglycerides, but HDL levels were normal. The fasting blood glucose group <126 mg / dl had a higher IFN-γ concentration than the group with fasting blood glucose levels ≥126 mg / dl. There was a significant difference in the concentration of IFN-γ between the two groups (p = 0.000). The group with triglyceride levels <150 mg / dl had lower IFN-γ levels than the group with triglyceride levels ≥ 150 mg / dl. There was a significant difference between the average IFN-γ concentration between those groups (p = 0.000). The fasting blood glucose levels ≥126 mg / dl and triglycerides levels ≥ 150 mg / dl had higher IFN-γ concentration than the group who had fasting blood glucose levels ≥126 mg / dl and triglycerides levels < 150 mg / dl. Conclusion: There are differences in IFN-γ concentrations in people with DM, increased fasting blood glucose and dyslipidemia compared to normal people. Keywords: IFN-γ, diabetes mellitus, dyslipidemia Abstrak Latar belakang: Penderita diabetes mellitus (DM) dan dyslipidemia mengalami inflamasi kronik yang ditandai dengan perubahan konsentrasi berbagai sitokin. Hal ini yang menyebabkan perubahan imunitas tubuh sehingga mudah mengalami infeksi. Salah satu sitokin yang paling berperan terhadap infeksi adalah interferon gamma (IFN-γ). Penelitian ini bertujuan untuk memeriksa konsentrasi IFN-γ pada penderita DM dan dislipidemia. Metode: Sebanyak 234 orang yang melakukan pengobatan di puskesmas di Kota Banda Aceh pada tahun 2019 diikutsertakan dalam penelitian ini. Dari setiap responden dilakukan pengambilan darah sebanyak 5 ml untuk dilakukan pemeriksaan kadar gula darah puasa (KGD P), trigliserida, high density lipoprotein (HDL), dan inrferon- gamma (IFN-γ). Pemeriksaan KGD, trigliserida, HDL dilakukan dengan metode enzimatik kolorimetrik. Pemeriksaan konsentrasi
背景:糖尿病(DM)患者以各种细胞分裂素浓度降低为特征发生慢性炎症。这会导致身体免疫力的变化,从而更容易感染。抗感染最重要的细胞因子之一是IFN-γ。本研究旨在测定糖尿病和血脂异常患者体内IFN-γ的浓度。方法:2019年在班达亚齐卫生中心接受治疗的234人被纳入本研究。从每个应答者身上抽取5毫升血液来检测空腹血糖、甘油三酯、高密度脂蛋白(HDL)和干扰素-γ (IFN-γ)。采用比色法测定空腹血糖、甘油三酯、高密度脂蛋白。采用夹心酶联免疫吸附试验(ELISA)技术检测IFN-γ蛋白浓度。结果:非DM组IFN-γ浓度明显高于DM组。非DM组IFN-γ平均浓度与DM组比较差异有统计学意义(p = 0.000)。所有糖尿病患者均有空腹血糖升高,大多数患者有高甘油三酯,但高密度脂蛋白水平正常。空腹血糖<126 mg / dl组IFN-γ浓度高于空腹血糖≥126 mg / dl组。两组间IFN-γ浓度差异有统计学意义(p = 0.000)。甘油三酯水平<150 mg / dl组IFN-γ水平低于甘油三酯水平≥150 mg / dl组。各组间IFN-γ平均浓度差异有统计学意义(p = 0.000)。空腹血糖≥126 mg / dl、甘油三酯≥150 mg / dl组IFN-γ浓度高于空腹血糖≥126 mg / dl、甘油三酯< 150 mg / dl组。结论:糖尿病患者IFN-γ浓度、空腹血糖升高、血脂异常与正常人相比存在差异。【关键词】IFN-γ,糖尿病,血脂异常【关键词】糖尿病,糖尿病,血脂异常【关键词】糖尿病,糖尿病,血脂异常;我是说,我是说,我是说,我是说,我是说,我是说,我是说,我是说。研究结果表明:Salah是影响阳平的主要因素,与干扰素γ (IFN-γ)有关。Penelitian ini bertujuan untuk memiksa konsentrasi IFN-γ与糖尿病和二脂血症有关。方法:Sebanyak 234 orang yang melakukan pengobatan di puskesmas di Kota Banda Aceh pada tahun 2019 diikutsertakan dalam penelitian ini。dilakukan pengambilan darah sebanyak 5 ml untuk dilakukan permeriksaan kadar gula darah puasa (KGD P),甘油三酯,高密度脂蛋白(HDL),丹干扰素-γ (IFN-γ)。Pemeriksaan KGD, trigliserida, HDL, dilakukan denengan方法,免疫比色法。酶联免疫吸附试验(ELISA);Hasil: Konsentrasi IFN-γ pada kelompok non-DM lebih tinggi dibandingkan dengan kelompok DM. Terdapat perbedaan and bermakna rata-rata Konsentrasi IFN-γ pada kelompok non-DM dibandingkan dengan kelompok DM (p= 0000)。Semua penderita DM mengalami peningkatan KGD P, sebagian besar mengalami hipertriglierida, namun kadar HDL正常。KGD P < 126mg /dl; KGD P < 126mg /dl; KGD P < 126mg /dl; KGD P < 126mg /dl;Terdapat perbedaa和bermakna perbedaa和konsentrasi IFN-γ antar kedua kelompok tersebut (p= 000)。Kelompok dengan kadar trigliserida < 150mg /dl memiliki kadar IFN-γ lebih rendah dibandingkan Kelompok dengan kadar trigliserida≥150mg /dl。Terdapat perbedaa和bermakna antara rata-rata konsentrasi konsentrasi IFN-γ antar kedua kelompok tersebut (p= 000)。巴旦木KGD P≥126 mg/dl丹甘油三酯≥150 mg/dl memiliki kadar IFN-γ yang lebih tinggi dibandingkan dengan kelpok KGD P≥126 mg/dl namun trigliserida <150 mg/dl。Terdapat perbedaa和bermakna antara rata-rata konsentrasi konsentrasi IFN-γ antar kedua kelompok tersebut (p= 000)。研究结果表明:1型糖尿病患者IFN-γ与糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病、糖尿病。Kata kunci: IFN-γ,糖尿病,二脂血症。
{"title":"Interferon gamma concentration in diabetes mellitus and dyslipidemia patient","authors":"Nelly Marissa, Marlinda Marlinda, Maulidar Maulidar, Veny Wilya, Nur Ramadhan, Zain Hadifah","doi":"10.22435/hsji.v12i2.4290","DOIUrl":"https://doi.org/10.22435/hsji.v12i2.4290","url":null,"abstract":"Background: Patient with diabetes mellitus (DM) occurs chronic inflammation by characterized a decreased concentration of various cytokinin types. This causes changes in the body’s immunity so that can be easier in having an infection. One of the most important cytokines against infection is IFN-γ. This study aimed to determine IFN-γ concentration in DM and dyslipidemia patients. \u0000Metode: An amount of 234 people who received treatment at the health center in Banda Aceh in 2019 were included in this study. From each respondent, 5 ml of blood was taken to check fasting blood glucose, triglycerides, high-density lipoproteins (HDL), and interferon-gamma (IFN-γ). Test of fasting blood glucose, triglycerides, HDL was carried out using the colorimetric enzymatic method. The IFN-γ protein concentration was examined using the sandwich enzyme-linked immunosorbent assay (ELISA) technique. \u0000Result: IFN-γ concentration in the non-DM group was higher than in the DM group. There was a significant difference between the average IFN-γ concentration in the non-DM group compared with the DM group (p = 0.000). All DM patients had increased fasting blood glucose, most had hypertriglycerides, but HDL levels were normal. The fasting blood glucose group <126 mg / dl had a higher IFN-γ concentration than the group with fasting blood glucose levels ≥126 mg / dl. There was a significant difference in the concentration of IFN-γ between the two groups (p = 0.000). The group with triglyceride levels <150 mg / dl had lower IFN-γ levels than the group with triglyceride levels ≥ 150 mg / dl. There was a significant difference between the average IFN-γ concentration between those groups (p = 0.000). The fasting blood glucose levels ≥126 mg / dl and triglycerides levels ≥ 150 mg / dl had higher IFN-γ concentration than the group who had fasting blood glucose levels ≥126 mg / dl and triglycerides levels < 150 mg / dl. \u0000Conclusion: There are differences in IFN-γ concentrations in people with DM, increased fasting blood glucose and dyslipidemia compared to normal people. \u0000Keywords: IFN-γ, diabetes mellitus, dyslipidemia \u0000 \u0000Abstrak \u0000Latar belakang: Penderita diabetes mellitus (DM) dan dyslipidemia mengalami inflamasi kronik yang ditandai dengan perubahan konsentrasi berbagai sitokin. Hal ini yang menyebabkan perubahan imunitas tubuh sehingga mudah mengalami infeksi. Salah satu sitokin yang paling berperan terhadap infeksi adalah interferon gamma (IFN-γ). Penelitian ini bertujuan untuk memeriksa konsentrasi IFN-γ pada penderita DM dan dislipidemia. \u0000Metode: Sebanyak 234 orang yang melakukan pengobatan di puskesmas di Kota Banda Aceh pada tahun 2019 diikutsertakan dalam penelitian ini. Dari setiap responden dilakukan pengambilan darah sebanyak 5 ml untuk dilakukan pemeriksaan kadar gula darah puasa (KGD P), trigliserida, high density lipoprotein (HDL), dan inrferon- gamma (IFN-γ). Pemeriksaan KGD, trigliserida, HDL dilakukan dengan metode enzimatik kolorimetrik. Pemeriksaan konsentrasi","PeriodicalId":30666,"journal":{"name":"Health Science Journal of Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48730681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-16DOI: 10.22435/hsji.v12i2.5529
A. Agustiningsih
Abstract Background: Multiplex real-time RT-PCR (rRT-PCR) is a fast, sensitive and specific test to detect more than one target in single PCR reaction. In this study we developed multiplex rRT-PCR for RSV-A and RSV-B since those viruses are the most common pathogen found in respiratory tract. However, in order to gain optimal reaction for RSV-A and RSV-B detection, the optimization of primers and probes specific for RSV-A and RSV B are needed. Method: The primers and probes of multiplex rRT-PCR for RSV-A and RSV-B were selected and optimized utilizing PerlPrimer software and BLAST to analyze the secondary structures and specificity, respectively. Further testing of selected primers and probes for rRT-PCR was done using annealing temperature based on in silico analysis as mentioned above. This includes sensitivity testing with the utilization of synthesized DNA of RSV-A and RSV-B and specificity testing targeting the common viruses found in respiratory tract. Results: The primer set and probes selected for RSV-A and RSV-B detection were specific only for RSV-A and RSV-B and showed no secondary structure. Based on primer and probe criteria for rRT-PCR such as annealing temperature, no secondary structure formed, % GC content and limit of detection, the multiplex rRT-PCR test using selected primers and probes was able to detect synthesized DNA of RSV-A and RSV-B. Conclusion: Multiplex rRT-PCR that employing primer sets and probes targeted N gene of RSV-A and RSV-B in this study were able to be detect RSV-A and RSV-B in single PCR reaction. Keyword: Multiplex, real-time RT-PCR, RSV-A, RSV-B Abstrak Latar belakang: Multiplex real-time RT-PCR (rRT-PCR) merupakan metode yang cepat, sensitif dan spesifik untuk mendeteksi lebih dari satu target pathogen dalam satu reaksi PCR. Penelitian ini bertujuan untuk mengembangkan multiplex rRT-PCR virus RSV-A dan RSV-B yang merupakan patogen yang paling sering ditemukan di saluran pernafasan. Optimisasi dari primer dan probe dalam multiplex rRT-PCR diperlukan untuk mendapatkan reaksi yang optimal dalam deteksi virus RSV-A dan RSV-B. Metode: Primer dan probe untuk multiplex rRT-PCR RSV-A dan RSV-B dipilih dan dioptimasi menggunakan software PerlPrimer dan BLAST untuk menganalisis adanya struktur sekunder serta spesifisitas dari primer dan probe. Uji multiplex rRT-PCR dilanjutkan berdasarkan suhu annealing berdasarkan hasil analisis menggunakan PerlPrimer. Uji sensitifitas dilakukan dengan menggunakan DNA sintetis dari RSV-A dan RSV-B dan uji spesifisitas dilakukan dengan mengetes primer dan probe terhadap virus-virus lain yang umumnya ditemukan di saluran pernafasan. Hasil: Primer dan probe yang dikembangkan pada penelitian ini tidak membentuk struktur sekunder dan spesifik mengamplifikasi hanya RSV-A dan RSV-B. Berdasarkan kriteria primer dan probe untuk digunakan dalam rRT-PCR yaitu suhu annealing, tidak adanya pembentukan struktur sekunder, % GC content serta detection limit, uji multiplex rRT-PCR yan
背景:多重实时RT-PCR (multiple real-time RT-PCR, rRT-PCR)是一种快速、灵敏、特异的检测方法,可在单次PCR反应中检测多个靶点。由于RSV-A和RSV-B是呼吸道中最常见的病原体,因此本研究建立了RSV-A和RSV-B的多重rRT-PCR。然而,为了获得检测RSV- a和RSV-B的最佳反应,需要对RSV- a和RSV-B特异性的引物和探针进行优化。方法:选择RSV-A和RSV-B多重rRT-PCR引物和探针,分别利用PerlPrimer软件和BLAST对引物和探针进行优化,分析二级结构和特异性。对rRT-PCR选择的引物和探针进行进一步的测试,根据上文的硅分析使用退火温度。这包括利用RSV-A和RSV-B的合成DNA进行敏感性测试,以及针对呼吸道常见病毒的特异性测试。结果:选择的RSV-A和RSV-B检测引物组和探针仅对RSV-A和RSV-B具有特异性,且无二级结构。根据rRT-PCR的引物和探针标准,如退火温度、未形成二级结构、GC含量%和检出限等,选择引物和探针进行多重rRT-PCR检测,能够检测到RSV-A和RSV-B的合成DNA。结论:本研究采用引物组和探针对RSV-A和RSV-B的N基因进行多重rRT-PCR,可在单次PCR反应中检测到RSV-A和RSV-B。【关键词】多重实时RT-PCR (rRT-PCR), RSV-A, RSV-B摘要:多重实时RT-PCR (rRT-PCR), merupakan方法,敏感和特异的检测方法;该病毒为RSV-A型和RSV-B型杨氏病致病菌,致病菌为杨氏病。Optimisasi dari引物dan探针dalam多重rRT-PCR diperlukan untuk mendapatkan reaksi yang最优dalam检测RSV-A和RSV-B病毒。Metode:丹引物探针为她多路复用rrt - pcr RSV-A丹RSV-B dipilih丹dioptimasi menggunakan软件PerlPrimer丹爆炸为她menganalisis adanya合写sekunder舒达spesifisitas达里语底漆丹探针。Uji多重rRT-PCR dilanjutkan berdasarkan suhu退火berdasarkan hasil分析menggunakan PerlPrimer。乌吉敏敏性dilakukan dengan menggunakan DNA sinintetis RSV-A和RSV-B,乌吉种特异性dilakukan dengan mengetes引物和探针terhadap病毒-病毒株yang umumnya diemukan di saluran pernafasan。【中文译文】:引物单探针yang dikembangkan pada penelitian ini在一种特殊的RSV-A和RSV-B下进行了研究。Berdasarkan标准引物dan探针untuk digunakan dalam rRT-PCR yitu suhu退火,tidak adanya pembentukan结构sekunder, % GC含量serta检测限,uji多重rRT-PCR yang dikembangkan pagada penelitian ini mampu mendeteksi DNA sintis RSV-A和RSV-B。kes脉冲an:多重rRT-PCR登根和孟古那坎引物和探针分离RSV-A和RSV-B,分离RSV-A和RSV-B,分离RSV-A和RSV-B,分离RSV-B。多路,实时RT-PCR, RSV-A, RSV-B
{"title":"Optimization of multiplex real-time RT-PCR for respiratory syncytial viruses detection","authors":"A. Agustiningsih","doi":"10.22435/hsji.v12i2.5529","DOIUrl":"https://doi.org/10.22435/hsji.v12i2.5529","url":null,"abstract":"Abstract \u0000Background: Multiplex real-time RT-PCR (rRT-PCR) is a fast, sensitive and specific test to detect more than one target in single PCR reaction. In this study we developed multiplex rRT-PCR for RSV-A and RSV-B since those viruses are the most common pathogen found in respiratory tract. However, in order to gain optimal reaction for RSV-A and RSV-B detection, the optimization of primers and probes specific for RSV-A and RSV B are needed. \u0000Method: The primers and probes of multiplex rRT-PCR for RSV-A and RSV-B were selected and optimized utilizing PerlPrimer software and BLAST to analyze the secondary structures and specificity, respectively. Further testing of selected primers and probes for rRT-PCR was done using annealing temperature based on in silico analysis as mentioned above. This includes sensitivity testing with the utilization of synthesized DNA of RSV-A and RSV-B and specificity testing targeting the common viruses found in respiratory tract. \u0000Results: The primer set and probes selected for RSV-A and RSV-B detection were specific only for RSV-A and RSV-B and showed no secondary structure. Based on primer and probe criteria for rRT-PCR such as annealing temperature, no secondary structure formed, % GC content and limit of detection, the multiplex rRT-PCR test using selected primers and probes was able to detect synthesized DNA of RSV-A and RSV-B. \u0000Conclusion: Multiplex rRT-PCR that employing primer sets and probes targeted N gene of RSV-A and RSV-B in this study were able to be detect RSV-A and RSV-B in single PCR reaction. \u0000Keyword: Multiplex, real-time RT-PCR, RSV-A, RSV-B \u0000 \u0000Abstrak \u0000Latar belakang: Multiplex real-time RT-PCR (rRT-PCR) merupakan metode yang cepat, sensitif dan spesifik untuk mendeteksi lebih dari satu target pathogen dalam satu reaksi PCR. Penelitian ini bertujuan untuk mengembangkan multiplex rRT-PCR virus RSV-A dan RSV-B yang merupakan patogen yang paling sering ditemukan di saluran pernafasan. Optimisasi dari primer dan probe dalam multiplex rRT-PCR diperlukan untuk mendapatkan reaksi yang optimal dalam deteksi virus RSV-A dan RSV-B. \u0000Metode: Primer dan probe untuk multiplex rRT-PCR RSV-A dan RSV-B dipilih dan dioptimasi menggunakan software PerlPrimer dan BLAST untuk menganalisis adanya struktur sekunder serta spesifisitas dari primer dan probe. Uji multiplex rRT-PCR dilanjutkan berdasarkan suhu annealing berdasarkan hasil analisis menggunakan PerlPrimer. Uji sensitifitas dilakukan dengan menggunakan DNA sintetis dari RSV-A dan RSV-B dan uji spesifisitas dilakukan dengan mengetes primer dan probe terhadap virus-virus lain yang umumnya ditemukan di saluran pernafasan. \u0000Hasil: Primer dan probe yang dikembangkan pada penelitian ini tidak membentuk struktur sekunder dan spesifik mengamplifikasi hanya RSV-A dan RSV-B. Berdasarkan kriteria primer dan probe untuk digunakan dalam rRT-PCR yaitu suhu annealing, tidak adanya pembentukan struktur sekunder, % GC content serta detection limit, uji multiplex rRT-PCR yan","PeriodicalId":30666,"journal":{"name":"Health Science Journal of Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43963443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-16DOI: 10.22435/hsji.v12i2.5295
A. Dewanto, Yudi Setyawan, V. Wardhani
Background: The COVID-19 pandemic hit Indonesia when hospitals were striving to adjust to a changing environment after a new health insurance system implementation, a government’s effort to achieve Universal Health Coverage. As a result, the pandemic forced hospitals to exploit their resources. Due to limited resources, setting accurate priorities is highly important to secure hospital operations and maintain its track towards the expected goals. This study aims to explore how deep the crisis impacts hospitals and how hospital leaders in Indonesia set their priorities in responding to the impact of this pandemic. Methods: This study used a descriptive and analytical approach. Data were collected through an online survey from hospital leaders and several documentary sources. Results: The results show that almost all hospital directors consider patient visits and hospital finance the most significant impacts of the COVID-19 pandemic. However, government hospital directors emphasize different areas compared to non-government hospital directors; the former sets their priorities on the hospital’s human resources, quality of service, and operations, while the latter focuses on the impact of patient visits and hospital finance. Conclusion: Although directors of government and non-governmental hospitals have a different emphasis, their priority is the same, maintaining hospital sustainability to provide quality services to people. Keywords: COVID-19 pandemic, hospital leaders’ perspective, impacts, Indonesia, priority setting Abstrak Latar belakang: Pandemi COVID-19 melanda Indonesia ketika rumah sakit berusaha menyesuaikan diri dengan lingkungan yang berubah setelah penerapan sistem jaminan kesehatan baru sebagai upaya pemerintah untuk mencapai Universal Health Coverage. Akibatnya, pandemi memaksa rumah sakit untuk mengeksploitasi sumber daya mereka. Sumber daya yang terbatas membuat penetapan prioritas yang akurat menjadi sangat penting untuk menjamin keberlangsungan operasional rumah sakit dan memastikan rumah sakit bergerak menuju tujuan yang diharapkan. Penelitian ini bertujuan untuk mengeksplorasi seberapa dalam dampak krisis ini terhadap rumah sakit dan bagaimana pemimpin rumah sakit di Indonesia menetapkan prioritasnya dalam merespon dampak pandemi ini. Metode: Penelitian ini menggunakan pendekatan deskriptif dan analitik. Data dikumpulkan melalui survei online dari pimpinan rumah sakit dan beberapa sumber dokumenter. Hasil: Hasil penelitian menunjukkan bahwa hampir semua direktur rumah sakit menganggap kunjungan pasien dan pembiayaan rumah sakit mendapat dampak paling signifikan dari pandemi COVID-19. Namun, direktur rumah sakit pemerintah menekankan bidang yang berbeda dibandingkan dengan direktur rumah sakit non-pemerintah. Direktur rumah sakit pemerintah menetapkan prioritas mereka pada sumber daya manusia rumah sakit, kualitas layanan, dan operasi, sedangkan direktur rumah sakit non-pemerintah fokus pada dampak kunjungan pasien d
{"title":"Priority setting in responding crisis: a hospital leaders’ perspective at the early stage of COVID-19 pandemic","authors":"A. Dewanto, Yudi Setyawan, V. Wardhani","doi":"10.22435/hsji.v12i2.5295","DOIUrl":"https://doi.org/10.22435/hsji.v12i2.5295","url":null,"abstract":"Background: The COVID-19 pandemic hit Indonesia when hospitals were striving to adjust to a changing environment after a new health insurance system implementation, a government’s effort to achieve Universal Health Coverage. As a result, the pandemic forced hospitals to exploit their resources. Due to limited resources, setting accurate priorities is highly important to secure hospital operations and maintain its track towards the expected goals. This study aims to explore how deep the crisis impacts hospitals and how hospital leaders in Indonesia set their priorities in responding to the impact of this pandemic. \u0000Methods: This study used a descriptive and analytical approach. Data were collected through an online survey from hospital leaders and several documentary sources. \u0000Results: The results show that almost all hospital directors consider patient visits and hospital finance the most significant impacts of the COVID-19 pandemic. However, government hospital directors emphasize different areas compared to non-government hospital directors; the former sets their priorities on the hospital’s human resources, quality of service, and operations, while the latter focuses on the impact of patient visits and hospital finance. \u0000Conclusion: Although directors of government and non-governmental hospitals have a different emphasis, their priority is the same, maintaining hospital sustainability to provide quality services to people. \u0000Keywords: COVID-19 pandemic, hospital leaders’ perspective, impacts, Indonesia, priority setting \u0000 \u0000Abstrak \u0000Latar belakang: Pandemi COVID-19 melanda Indonesia ketika rumah sakit berusaha menyesuaikan diri dengan lingkungan yang berubah setelah penerapan sistem jaminan kesehatan baru sebagai upaya pemerintah untuk mencapai Universal Health Coverage. Akibatnya, pandemi memaksa rumah sakit untuk mengeksploitasi sumber daya mereka. Sumber daya yang terbatas membuat penetapan prioritas yang akurat menjadi sangat penting untuk menjamin keberlangsungan operasional rumah sakit dan memastikan rumah sakit bergerak menuju tujuan yang diharapkan. Penelitian ini bertujuan untuk mengeksplorasi seberapa dalam dampak krisis ini terhadap rumah sakit dan bagaimana pemimpin rumah sakit di Indonesia menetapkan prioritasnya dalam merespon dampak pandemi ini. \u0000Metode: Penelitian ini menggunakan pendekatan deskriptif dan analitik. Data dikumpulkan melalui survei online dari pimpinan rumah sakit dan beberapa sumber dokumenter. \u0000Hasil: Hasil penelitian menunjukkan bahwa hampir semua direktur rumah sakit menganggap kunjungan pasien dan pembiayaan rumah sakit mendapat dampak paling signifikan dari pandemi COVID-19. Namun, direktur rumah sakit pemerintah menekankan bidang yang berbeda dibandingkan dengan direktur rumah sakit non-pemerintah. Direktur rumah sakit pemerintah menetapkan prioritas mereka pada sumber daya manusia rumah sakit, kualitas layanan, dan operasi, sedangkan direktur rumah sakit non-pemerintah fokus pada dampak kunjungan pasien d","PeriodicalId":30666,"journal":{"name":"Health Science Journal of Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48456017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-16DOI: 10.22435/hsji.v12i2.3315
Wahyu Febrianto, Menis Rahmawati, I. Sastrawan, T. Hariyanti
Background: Patient safety is the main issue in healthcare services nowadays. Delaying to inform the critical value of laboratory results is a significant source of harm for the patient. The aim of this study is to compare the timeliness of laboratory critical value reporting before and after re-accreditation as one of the service quality indicators in Hospital X. Methods: This study was done by using observational cross-sectional in Hospital X on January - February 2020 with total sampling method of critical value reporting to the responsible clinician that originated from Intensive Care Unit (ICU), Verlos Kamer (VK), and inpatient ward (IW) 1-6 from January-December 2019. The timeliness of reporting was counted since the laboratory result was obtained until received by the responsible clinician within £ 30 minutes and categorized as "On time" or "Late". Results: During 2019, there were 816 reporting which has been done before re-accreditation (511) and after re-accreditation (305) with 17 kinds of tests. The most reported test was platelet with 349 (before re-accreditation) and 101 (after re-accreditation), whilst SGOT/SGPT and albumin were the fewest one. The lowest timeliness of reporting percentage was 76,00% (February), whilst the highest was 98,48% (November). The timeliness of reporting's percentage was 84,34% (before re-accreditation) and 94,43% (after re-accreditation). The statistical analysis result revealed Pearson Chi-Square correlation was 18,535 with significance 0,000 and 3,145 odds ratio which shows that re-accreditation could significantly increase the timeliness of critical value reporting three times. Conclusion: This result showed that re-accreditation could affect the timeliness of laboratory critical value reporting to the responsible clinicians. Keywords: re-accreditation, critical value, laboratory, patient safety, hospital Abstrak Latar belakang: Keselamatan pasien merupakan isu utama dalam pelayanan kesehatan. Tertundanya komunikasi hasil nilai kritis laboratorium merupakan sumber bahaya yang signifikan terhadap pasien. Penelitian ini bertujuan untuk membandingkan ketepatan waktu pelaporan nilai kritis laboratorium sebelum dan setelah reakreditasi sebagai salah satu indikator mutu di RS X. Metode: Penelitian dilakukan dengan cara observasional dengan metode cross sectional di RS X pada Januari - Februari 2020 dengan total sampling laporan nilai kritis kepada Dokter Penanggung Jawab Pasien (DPJP) yang berasal dari ruang Intensive Care Unit (ICU), Verlos Kamer (VK), dan ruang rawat inap 1 – 6 sejak Januari – Desember 2019. Ketepatan waktu pelaporan dihitung sejak hasil pemeriksaan didapatkan hingga diterima oleh DPJP dalam waktu £ 30 menit dan dinyatakan sebagai "Tepat Waktu" atau "Terlambat". Hasil: Selama tahun 2019, terdapat 816 pelaporan yang dilakukan sebelum akreditasi (511) dan setelahnya (305) dengan 17 jenis pemeriksaan. Pemeriksaan trombosit menjadi yang paling banyak dilaporkan yaitu 349 (sebelum ak
背景:患者安全是当今医疗服务中的主要问题。延迟告知实验室结果的临界值是对患者造成伤害的重要来源。本研究的目的是比较X医院作为服务质量指标之一的实验室临界值报告在重新认证前后的及时性。方法:本研究于2020年1月至2月在X医院使用观察性横断面进行,采用临界值总抽样法向2019年1月12月至12月来自重症监护室(ICU)、Verlos Kamer(VK)和住院病房(IW)1-6的负责临床医生报告。报告的及时性从获得实验室结果开始计算,直到责任临床医生在30分钟内收到,并被归类为“准时”或“迟到”。结果:2019年,共有816份报告,在重新认证之前(511份)和重新认证之后(305份)进行了17种类型的测试。报告最多的检测是血小板,349次(在重新认证之前)和101次(在再次认证之后),而SGOT/SGPT和白蛋白是最少的。报告及时性百分比最低的是7600%(2月),而最高的是98,48%(11月)。报告的及时性百分比为84,34%(重新认证前)和94,43%(重新认证后)。统计分析结果显示,Pearson Chi Square相关性为18535,显著性为0000,优势比为3145。这表明重新认证可以显著提高临界值报告的及时性三倍。结论:这一结果表明,重新认证可能会影响向负责任的临床医生报告实验室临界值的及时性。关键词:再鉴定、临界值、实验室、患者安全、医院事实证明,实验室临界值的交流对患者来说是一个重要的危险来源。本研究的目的是比较实验室临界值报告作为RS X的核心指标之一重新计入之前和之后的准确性。方法:该研究于2020年1-2月在RS X中采用横断面方法进行,自2019年1-12月以来,对重症监护室(ICU)、Verlos Kamer(VK)和1-6家医院的患者反应医生(DPJP)的临界值报告进行了总抽样。报告的速度根据DPJP在30分钟内接受的检查结果计算,并指定为“准确时间”或“延迟”。结果:2019年,在认证前(511)和认证后(305)共进行了816次报告,共进行了17种类型的检查。最常报告的血栓形成为349例(认证前)和101例(认证后),而SGOT/SGPT和白蛋白最低。报告准确率最低为76.00%(2月),最高为98.48%(11月)。报告时间的准确率分别为84.34%(认证前)和94.43%(认证后)。统计分析结果显示,皮尔逊-卡方相关性为18535,显著性为0000,奇数比为3145,这表明重新认证可以将临界值报告准确性提高三倍的概率。结论:这表明重新认证会影响向DPJP报告关键实验室值的准确性。关键词:再认证,临界值,实验室,患者安全,医院。
{"title":"The importance of hospital re-accreditation: improving the timeliness of laboratory critical value reporting","authors":"Wahyu Febrianto, Menis Rahmawati, I. Sastrawan, T. Hariyanti","doi":"10.22435/hsji.v12i2.3315","DOIUrl":"https://doi.org/10.22435/hsji.v12i2.3315","url":null,"abstract":"Background: Patient safety is the main issue in healthcare services nowadays. Delaying to inform the critical value of laboratory results is a significant source of harm for the patient. The aim of this study is to compare the timeliness of laboratory critical value reporting before and after re-accreditation as one of the service quality indicators in Hospital X. \u0000Methods: This study was done by using observational cross-sectional in Hospital X on January - February 2020 with total sampling method of critical value reporting to the responsible clinician that originated from Intensive Care Unit (ICU), Verlos Kamer (VK), and inpatient ward (IW) 1-6 from January-December 2019. The timeliness of reporting was counted since the laboratory result was obtained until received by the responsible clinician within £ 30 minutes and categorized as \"On time\" or \"Late\". \u0000Results: During 2019, there were 816 reporting which has been done before re-accreditation (511) and after re-accreditation (305) with 17 kinds of tests. The most reported test was platelet with 349 (before re-accreditation) and 101 (after re-accreditation), whilst SGOT/SGPT and albumin were the fewest one. The lowest timeliness of reporting percentage was 76,00% (February), whilst the highest was 98,48% (November). The timeliness of reporting's percentage was 84,34% (before re-accreditation) and 94,43% (after re-accreditation). The statistical analysis result revealed Pearson Chi-Square correlation was 18,535 with significance 0,000 and 3,145 odds ratio which shows that re-accreditation could significantly increase the timeliness of critical value reporting three times. \u0000Conclusion: This result showed that re-accreditation could affect the timeliness of laboratory critical value reporting to the responsible clinicians. \u0000Keywords: re-accreditation, critical value, laboratory, patient safety, hospital \u0000 \u0000Abstrak \u0000Latar belakang: Keselamatan pasien merupakan isu utama dalam pelayanan kesehatan. Tertundanya komunikasi hasil nilai kritis laboratorium merupakan sumber bahaya yang signifikan terhadap pasien. Penelitian ini bertujuan untuk membandingkan ketepatan waktu pelaporan nilai kritis laboratorium sebelum dan setelah reakreditasi sebagai salah satu indikator mutu di RS X. \u0000Metode: Penelitian dilakukan dengan cara observasional dengan metode cross sectional di RS X pada Januari - Februari 2020 dengan total sampling laporan nilai kritis kepada Dokter Penanggung Jawab Pasien (DPJP) yang berasal dari ruang Intensive Care Unit (ICU), Verlos Kamer (VK), dan ruang rawat inap 1 – 6 sejak Januari – Desember 2019. Ketepatan waktu pelaporan dihitung sejak hasil pemeriksaan didapatkan hingga diterima oleh DPJP dalam waktu £ 30 menit dan dinyatakan sebagai \"Tepat Waktu\" atau \"Terlambat\". \u0000Hasil: Selama tahun 2019, terdapat 816 pelaporan yang dilakukan sebelum akreditasi (511) dan setelahnya (305) dengan 17 jenis pemeriksaan. Pemeriksaan trombosit menjadi yang paling banyak dilaporkan yaitu 349 (sebelum ak","PeriodicalId":30666,"journal":{"name":"Health Science Journal of Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49230956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-16DOI: 10.22435/hsji.v12i2.5467
Tities Puspita, A. Suryatma, O. S. Simarmata, G. Veridona, Heny Lestary, Athena Athena, I. Pambudi, S. Sulistyo, T. Pakasi
Background: As the second-highest country in tuberculosis (TB) cases globally, Indonesia has experienced an increasing trend of notification rate in the last ten years; however, the 34 provinces may have different risks. This study aims to examine TB risk variation across Indonesia in 2010-2019. Methods: A descriptive analysis was conducted on TB routine data of 2010-2019 from the Ministry of Health. Cases included all types of TB patients. Total cases, incidence rate (IR), and standardized morbidity ratio (SMR) were calculated for each province and national level during the period. Distributions of IRs and SMRs were displayed on maps. Results: During 2010-2019, 3,866,447 TB cases occurred in Indonesia, and the national IR was 1,523 per 100,000 populations. The highest proportion of cases and IR were in West Java (20.6%, 314 per 100,000); while the lowest was in North Kalimantan (0.2%, 3 per 100,000). Higher risks of TB occurred in DKI Jakarta (SMR 1.9), Papua (1.7), North Sulawesi (1.7), Maluku (1.5) and West Papua (1.5) among others. The smallest SMRs were found in Bali and Yogyakarta (0.5). Conclusion: TB risk varied across Indonesia in 2010-2019, with a higher risk in DKI Jakarta and several provinces in eastern Indonesia. Given the underreporting nature of routine data, validation is required when using the finding of this study in the local-level intervention. Keywords: tuberculosis, TB, standardized morbidity ratio, spatial variation, risk Abstrak Latar belakang: Sebagai negara dengan jumlah kasus tuberkulosis (TB) terbesar kedua di dunia, Indonesia menunjukkan tren peningkatan notification rate di sepuluh tahun terakhir. Akan tetapi, risiko TB di 34 provinsi bisa saja berbeda-beda. Artikel ini bertujuan mengkaji variasi risiko TB di Indonesia pada tahun 2010-2019. Metode: Data rutin TB tahun 2010-2019 dari Kementerian Kesehatan dianalisis secara deskriptif. Kasus TB didefinisikan sebagai semua tipe pasien TB. Total jumlah kasus, incidence rate (IR), dan standardized morbidity ratio (SMR) dihitung untuk tiap provinsi dan tingkat nasional selama periode tersebut. Sebaran IR dan SMR diplot di atas peta. Hasil: Selama 2010-2019, terdapat 3.866.447 kasus TB dan IR nasional 1.523 per 100.000 populasi. Proporsi kasus dan IR terbesar ada di Jawa Barat (20,6%, 314 per 100.000) dan terkecil di Kalimantan Utara (0,2%, 3 per 100.000). Risiko TB lebih tinggi di antaranya terjadi di DKI Jakarta (SMR 1,9), Papua (1,7), Sulawesi Utara (1,7), Maluku (1,5) dan Papua Barat (1,5). Standardized Morbidity Ratio terendah ditemukan di Bali dan Yogyakarta (0,5). Kesimpulan: Dapat disimpulkan bahwa risiko TB beragam di seluruh Indonesia selama 2010-2019, di mana DKI Jakarta dan beberapa provinsi di timur Indonesia memiliki risiko lebih tinggi. Mengingat adanya kurang lapor dalam data rutin, validasi diperlukan jika menggunakan temuan studi ini dalam intervensi di tingkat lokal. Kata kunci: tuberkulosis, TB, standardized morbidity ratio, variasi spasia
{"title":"Spatial variation of tuberculosis risk in Indonesia 2010-2019","authors":"Tities Puspita, A. Suryatma, O. S. Simarmata, G. Veridona, Heny Lestary, Athena Athena, I. Pambudi, S. Sulistyo, T. Pakasi","doi":"10.22435/hsji.v12i2.5467","DOIUrl":"https://doi.org/10.22435/hsji.v12i2.5467","url":null,"abstract":"Background: As the second-highest country in tuberculosis (TB) cases globally, Indonesia has experienced an increasing trend of notification rate in the last ten years; however, the 34 provinces may have different risks. This study aims to examine TB risk variation across Indonesia in 2010-2019. \u0000Methods: A descriptive analysis was conducted on TB routine data of 2010-2019 from the Ministry of Health. Cases included all types of TB patients. Total cases, incidence rate (IR), and standardized morbidity ratio (SMR) were calculated for each province and national level during the period. Distributions of IRs and SMRs were displayed on maps. \u0000Results: During 2010-2019, 3,866,447 TB cases occurred in Indonesia, and the national IR was 1,523 per 100,000 populations. The highest proportion of cases and IR were in West Java (20.6%, 314 per 100,000); while the lowest was in North Kalimantan (0.2%, 3 per 100,000). Higher risks of TB occurred in DKI Jakarta (SMR 1.9), Papua (1.7), North Sulawesi (1.7), Maluku (1.5) and West Papua (1.5) among others. The smallest SMRs were found in Bali and Yogyakarta (0.5). \u0000Conclusion: TB risk varied across Indonesia in 2010-2019, with a higher risk in DKI Jakarta and several provinces in eastern Indonesia. Given the underreporting nature of routine data, validation is required when using the finding of this study in the local-level intervention. \u0000Keywords: tuberculosis, TB, standardized morbidity ratio, spatial variation, risk \u0000 \u0000Abstrak \u0000Latar belakang: Sebagai negara dengan jumlah kasus tuberkulosis (TB) terbesar kedua di dunia, Indonesia menunjukkan tren peningkatan notification rate di sepuluh tahun terakhir. Akan tetapi, risiko TB di 34 provinsi bisa saja berbeda-beda. Artikel ini bertujuan mengkaji variasi risiko TB di Indonesia pada tahun 2010-2019. \u0000Metode: Data rutin TB tahun 2010-2019 dari Kementerian Kesehatan dianalisis secara deskriptif. Kasus TB didefinisikan sebagai semua tipe pasien TB. Total jumlah kasus, incidence rate (IR), dan standardized morbidity ratio (SMR) dihitung untuk tiap provinsi dan tingkat nasional selama periode tersebut. Sebaran IR dan SMR diplot di atas peta. \u0000Hasil: Selama 2010-2019, terdapat 3.866.447 kasus TB dan IR nasional 1.523 per 100.000 populasi. Proporsi kasus dan IR terbesar ada di Jawa Barat (20,6%, 314 per 100.000) dan terkecil di Kalimantan Utara (0,2%, 3 per 100.000). Risiko TB lebih tinggi di antaranya terjadi di DKI Jakarta (SMR 1,9), Papua (1,7), Sulawesi Utara (1,7), Maluku (1,5) dan Papua Barat (1,5). Standardized Morbidity Ratio terendah ditemukan di Bali dan Yogyakarta (0,5). \u0000Kesimpulan: Dapat disimpulkan bahwa risiko TB beragam di seluruh Indonesia selama 2010-2019, di mana DKI Jakarta dan beberapa provinsi di timur Indonesia memiliki risiko lebih tinggi. Mengingat adanya kurang lapor dalam data rutin, validasi diperlukan jika menggunakan temuan studi ini dalam intervensi di tingkat lokal. \u0000Kata kunci: tuberkulosis, TB, standardized morbidity ratio, variasi spasia","PeriodicalId":30666,"journal":{"name":"Health Science Journal of Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45806988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-16DOI: 10.22435/hsji.v12i2.5356
N. Aryastami, P. P. Arfines, V. Setiawaty, S. Isfandari
Background: The immunization program in Indonesia has been implemented since 1956 started to eradicate smallpox and expanded until 1980, including Measles. The timely and complete implementation of basic immunization is the main strategy to protect the population, including outbreak prevention. The purpose of this study is to determine the level immunity of Measles antibody as the outcome of completed basic immunization and its contributors in children aged 12-36 months. Methods: This study is a secondary data analysis of the Indonesia Basic Health Survey (RISKESDAS) 2013. The analysis was carried out on a serological sample of the antibody titer of children aged 12-36 months, totaling 229 samples. The sample inclusion criteria were children who had complete sociodemographics data, basic immunization records and Measles antibody titer data. Measles examination was carried out using the Enzyme-Linked Immunosorbent Assay (ELISA) method. Results: Incomplete immunization, being a boy, and lack of cleanliness in the family room were significantly associated with lower measles antibody levels in children. Having each variable controlled, completeness of immunization (OR=1,99; p=0.018; 95% CI=1.124-3.544) and gender of boy (OR=2.0; p=0.016; 95% CI=1.137-3.515) remain as significant variables for antibody’s titer. Conclusion: The completeness of immunization has a significant association towards titer antibody of Measles in children. Immunization completeness is an actual effort to reach herd immunity in children and to prevent measles outbreak in the community. Adequate health promotion is needed to change people's behavior to believe in the safety and importance of implementing complete basic immunization for children even in pandemic conditions. Keywords: antibody titer, immunization, children aged 12-36 months, Indonesia, measles Abstrak Latar belakang: Program imunisasi di Indonesia telah dilaksanakan sejak tahun 1956 yang dimulai dengan pemberantasan cacar yang diperluas hingga tahun 1980, termasuk campak. Pelaksanaan imunisasi dasar yang tepat waktu dan lengkap merupakan strategi utama untuk perlindungan penduduk, termasuk pencegahan Kejadian Luar Biasa (KLB). Tujuan dari penelitian ini untuk mengetahui tingkatan kekebalan antibodi Campak sebagai hasil dari kelengkapan imunisasi dasar dan faktor yang berkontribusi pada anak usia 12-36 bulan. Metode: Penelitian ini merupakan analisis data sekunder Riset Kesehatan Dasar Indonesia (RISKESDAS) 2013. Analisis dilakukan pada sampel serologi titer antibodi anak usia 12-36 bulan yang berjumlah 229 sampel. Kriteria inklusi sampel adalah anak yang memiliki data sosiodemografi lengkap, catatan imunisasi dasar dan data titer antibodi Campak. Pemeriksaan campak dilakukan dengan metode Enzyme-Linked Immunosorbent Assay (ELISA). Hasil: Imunisasi yang tidak lengkap, berjenis kelamin laki-laki, dan kurangnya kebersihan di ruang keluarga berhubungan bermakna dengan rendahnya tingkat antibodi campak pad
{"title":"Factors associated with measles antibody titers in children aged 12-36 months in Indonesia: an analysis of National Health Research 2013","authors":"N. Aryastami, P. P. Arfines, V. Setiawaty, S. Isfandari","doi":"10.22435/hsji.v12i2.5356","DOIUrl":"https://doi.org/10.22435/hsji.v12i2.5356","url":null,"abstract":"Background: The immunization program in Indonesia has been implemented since 1956 started to eradicate smallpox and expanded until 1980, including Measles. The timely and complete implementation of basic immunization is the main strategy to protect the population, including outbreak prevention. The purpose of this study is to determine the level immunity of Measles antibody as the outcome of completed basic immunization and its contributors in children aged 12-36 months. \u0000Methods: This study is a secondary data analysis of the Indonesia Basic Health Survey (RISKESDAS) 2013. The analysis was carried out on a serological sample of the antibody titer of children aged 12-36 months, totaling 229 samples. The sample inclusion criteria were children who had complete sociodemographics data, basic immunization records and Measles antibody titer data. Measles examination was carried out using the Enzyme-Linked Immunosorbent Assay (ELISA) method. \u0000Results: Incomplete immunization, being a boy, and lack of cleanliness in the family room were significantly associated with lower measles antibody levels in children. Having each variable controlled, completeness of immunization (OR=1,99; p=0.018; 95% CI=1.124-3.544) and gender of boy (OR=2.0; p=0.016; 95% CI=1.137-3.515) remain as significant variables for antibody’s titer. \u0000Conclusion: The completeness of immunization has a significant association towards titer antibody of Measles in children. Immunization completeness is an actual effort to reach herd immunity in children and to prevent measles outbreak in the community. Adequate health promotion is needed to change people's behavior to believe in the safety and importance of implementing complete basic immunization for children even in pandemic conditions. \u0000Keywords: antibody titer, immunization, children aged 12-36 months, Indonesia, measles \u0000 \u0000Abstrak \u0000Latar belakang: Program imunisasi di Indonesia telah dilaksanakan sejak tahun 1956 yang dimulai dengan pemberantasan cacar yang diperluas hingga tahun 1980, termasuk campak. Pelaksanaan imunisasi dasar yang tepat waktu dan lengkap merupakan strategi utama untuk perlindungan penduduk, termasuk pencegahan Kejadian Luar Biasa (KLB). Tujuan dari penelitian ini untuk mengetahui tingkatan kekebalan antibodi Campak sebagai hasil dari kelengkapan imunisasi dasar dan faktor yang berkontribusi pada anak usia 12-36 bulan. \u0000Metode: Penelitian ini merupakan analisis data sekunder Riset Kesehatan Dasar Indonesia (RISKESDAS) 2013. Analisis dilakukan pada sampel serologi titer antibodi anak usia 12-36 bulan yang berjumlah 229 sampel. Kriteria inklusi sampel adalah anak yang memiliki data sosiodemografi lengkap, catatan imunisasi dasar dan data titer antibodi Campak. Pemeriksaan campak dilakukan dengan metode Enzyme-Linked Immunosorbent Assay (ELISA). \u0000Hasil: Imunisasi yang tidak lengkap, berjenis kelamin laki-laki, dan kurangnya kebersihan di ruang keluarga berhubungan bermakna dengan rendahnya tingkat antibodi campak pad","PeriodicalId":30666,"journal":{"name":"Health Science Journal of Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46327059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-19DOI: 10.22435/hsji.v12i1.4754
Ika Saptarini, N. Novianti, Anissa Rizkianti, Iram Barida Maisya, S. Suparmi, G. Veridona, Ning Sulistiyowati, Sudikno Sudikno
Background: COVID-19, which started in Wuhan, has become a global pandemic leading to a new global risk to human health. Lack of information or misinformation about COVID-19 can lead to stigmatization, including for health workers. This study aims to determine the stigmatization among health workers during the COVID-19 pandemic within the Greater Jakarta Metropolitan Area. Methods: This study was a cross-sectional study conducted online using Google Forms in the Jabodetabek area. The questionnaire’s link was distributed through social media, including Whatsapp, Facebook, Twitter, and Instagram. The study sample is health workers who live in Jabodetabek and carry out health practices. Stigma is measured using four dimensions: personalized stigma, disclosure concerns, public attitudes, and negative self-image. Result: The negative self-image dimension is the dimension most felt by health workers. More than half of health workers agreed that during the COVID-19 pandemic, they put their families at risk because of their status as health workers. The stigma of health workers who work in hospitals is higher than that of non-hospital health workers, such as health centers, clinics, and laboratories. Conclusion: There was any stigmatization among healthcare workers in Greater Jakarta Metropolitan Area. Stigmatization was higher among healthcare workers who work in hospitals compared to those who work in non-hospitals. Some efforts should be made to reduce stigmatization among health workers, such as provide correct information to the public, equip health personnel with adequate personal protective equipment, and give incentives periodically to the health workers. Keywords: Stigma, COVID-19, healthcare workers, Greater Jakarta Metropolitan Area Abstrak Latar belakang: COVID-19 yang bermula dari Wuhan telah menjadi pandemi global yang mengancam kesehatan umat manusia. Kurangnya informasi atau informasi yang salah mengenai COVID-19 dapat menyebabkan adanya stigmatisasi termasuk terhadap tenaga kesehatan. Penelitian ini menilai adanya stigmatisasi terhadap tenaga kesehatan selama pandemi COVID-19 di wilayah Jabodetabek. Metode: Penelitian ini merupakan penelitian potong lintang dan dilakukan secara daring menggunakan Google Form di wilayah Jabodetabek. Tautan pengisian kuesioner disebarkan melalui media sosial seperti Whatsapp, Facebook, Twitter dan Instagram. Sampel studi adalah tenaga kesehatan yang tinggal di Jabodetabek dan melakukan praktik kesehatan. Stigma diukur menggunakan empat dimensi yaitu personized stigma, disclosure concerns, concerns about public attitudes dan negative self-image. Hasil: Dimensi negative self-image merupakan dimensi yang paling dirasakan oleh tenaga kesehatan. Lebih dari separuh tenaga kesehatan setuju bahwa selama pandemi COVID-19 mereka membahayakan keluarga mereka karena status mereka sebagai tenaga kesehatan. Stigma pada tenaga kesehatan yang bekerja di rumah sakit lebih tinggi disbanding tenaga kesehatan
{"title":"Stigma during COVID-19 pandemic among healthcare workers in greater Jakarta metropolitan area: a cross-sectional online study","authors":"Ika Saptarini, N. Novianti, Anissa Rizkianti, Iram Barida Maisya, S. Suparmi, G. Veridona, Ning Sulistiyowati, Sudikno Sudikno","doi":"10.22435/hsji.v12i1.4754","DOIUrl":"https://doi.org/10.22435/hsji.v12i1.4754","url":null,"abstract":"Background: COVID-19, which started in Wuhan, has become a global pandemic leading to a new global risk to human health. Lack of information or misinformation about COVID-19 can lead to stigmatization, including for health workers. This study aims to determine the stigmatization among health workers during the COVID-19 pandemic within the Greater Jakarta Metropolitan Area. Methods: This study was a cross-sectional study conducted online using Google Forms in the Jabodetabek area. The questionnaire’s link was distributed through social media, including Whatsapp, Facebook, Twitter, and Instagram. The study sample is health workers who live in Jabodetabek and carry out health practices. Stigma is measured using four dimensions: personalized stigma, disclosure concerns, public attitudes, and negative self-image. Result: The negative self-image dimension is the dimension most felt by health workers. More than half of health workers agreed that during the COVID-19 pandemic, they put their families at risk because of their status as health workers. The stigma of health workers who work in hospitals is higher than that of non-hospital health workers, such as health centers, clinics, and laboratories. Conclusion: There was any stigmatization among healthcare workers in Greater Jakarta Metropolitan Area. Stigmatization was higher among healthcare workers who work in hospitals compared to those who work in non-hospitals. Some efforts should be made to reduce stigmatization among health workers, such as provide correct information to the public, equip health personnel with adequate personal protective equipment, and give incentives periodically to the health workers. Keywords: Stigma, COVID-19, healthcare workers, Greater Jakarta Metropolitan Area Abstrak Latar belakang: COVID-19 yang bermula dari Wuhan telah menjadi pandemi global yang mengancam kesehatan umat manusia. Kurangnya informasi atau informasi yang salah mengenai COVID-19 dapat menyebabkan adanya stigmatisasi termasuk terhadap tenaga kesehatan. Penelitian ini menilai adanya stigmatisasi terhadap tenaga kesehatan selama pandemi COVID-19 di wilayah Jabodetabek. Metode: Penelitian ini merupakan penelitian potong lintang dan dilakukan secara daring menggunakan Google Form di wilayah Jabodetabek. Tautan pengisian kuesioner disebarkan melalui media sosial seperti Whatsapp, Facebook, Twitter dan Instagram. Sampel studi adalah tenaga kesehatan yang tinggal di Jabodetabek dan melakukan praktik kesehatan. Stigma diukur menggunakan empat dimensi yaitu personized stigma, disclosure concerns, concerns about public attitudes dan negative self-image. Hasil: Dimensi negative self-image merupakan dimensi yang paling dirasakan oleh tenaga kesehatan. Lebih dari separuh tenaga kesehatan setuju bahwa selama pandemi COVID-19 mereka membahayakan keluarga mereka karena status mereka sebagai tenaga kesehatan. Stigma pada tenaga kesehatan yang bekerja di rumah sakit lebih tinggi disbanding tenaga kesehatan ","PeriodicalId":30666,"journal":{"name":"Health Science Journal of Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44257568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-19DOI: 10.22435/hsji.v12i1.4879
Pompini Agustina Sitompul, N. Mariana, A. Rusli
Background: During the early period of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic, there was no approved and definitive drug available for the treatment of COVID-19. Favipiravir, chloroquine, hydroxychloroquine was used for re-purposing drugs while their efficacy and safety remained a major concern for healthcare workers. Clinical trial to assess efficacy and safety were ongoing. Case presentation: We present here the case of a 38-year-old woman, the first case of a healthcare worker diagnosed with COVID-19 who had moderate type, including first experience treatment with favipiravir in Sulianti Saroso Infectious Disease Hospital, Jakarta, Indonesia. We present the clinical characteristics, chest X-ray, clinical laboratory profiles, the treatment process with favipiravir and hydroxychloroquine as well as the clinical outcome of moderate type COVID-19 patient. Conclusion: This case highlights that considering the use of emergency intervention outside of clinical trial in the COVID-19 population, the informed patient consent has been given and the use of emergency intervention was monitored. Keywords: COVID-19, favipiravir, medical worker, case report, Jakarta Abstrak Latar belakang: Periode awal pandemi Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), belum terdapat obat yang disetujui dan pasti tersedia untuk pengobatan COVID-19. Favipiravir, chloroquine, hydroxychloroquine digunakan sebagai obat dengan indikasi baru yang sementara efektifitas dan keamanannya menjadi perhatian para petugas medis. Penyajian kasus: Disini kami melaporkan kasus wanita umur 38 tahun, merupakan kasus pertama seorang tenaga kesehatan Rumah Sakit terdiagnosis Coronavirus Disease 2019 (COVID-19) dengan penggunaan terapi favipiravir untuk pertama kalinya di Rumah Sakit Pusat Infeksi Sulianti Saroso, Jakarta, Indonesia. Berikut ini kami gambarkan karakteristik klinis, hasil foto thorak, profil laboratorium dan proses terapi menggunakan favipiravir and hidroxychloroquine serta hasil akhir pada kasus COVID-19 derajat sedang. Kesimpulan: Kasus ini menggaribawahi bahwa pertimbangan penggunaan kegawatdaruratan obat antivirus diluar uji klinis pada populasi pasien COVID-19, pasien telah memberikan persetujuan dan penggunaan obat-obat tersebut dimonitor. Kata kunci: Covid-19, favipiravir, tenaga kesehatan, laporan kasus, Jakarta
背景:在严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)大流行的早期,没有批准和确定的药物可用于治疗COVID-19。法匹拉韦、氯喹和羟氯喹被用于重新利用药物,而它们的有效性和安全性仍然是卫生保健工作者关注的主要问题。评估疗效和安全性的临床试验正在进行中。病例介绍:我们在这里介绍一名38岁妇女的病例,这是第一例被诊断为COVID-19的中度型卫生保健工作者,包括在印度尼西亚雅加达Sulianti Saroso传染病医院首次接受法匹拉韦治疗。介绍1例中重度COVID-19患者的临床特点、胸片、临床实验室资料、法匹拉韦联合羟氯喹治疗过程及临床转归。结论:本病例强调,考虑到COVID-19人群在临床试验之外使用紧急干预措施,已获得患者知情同意并监测紧急干预措施的使用情况。关键词:COVID-19,法匹拉韦,医务工作者,病例报告,雅加达摘要:周期性大流行的严重急性呼吸综合征冠状病毒2 (SARS-CoV-2), belum terdapat bata yang disetujui和pasti tersedia untuk pengobatan COVID-19。法匹拉韦、氯喹、羟氯喹的研究进展。Penyajian kasus: Disini kami melaporkan kasus wanita umur 38 tahun, merupakan kasus pertama seorang tenaga kesehatan Rumah Sakit诊断冠状病毒病2019 (COVID-19) dengan penggunaan terapi favipiravir untuk pertama kalinya di Rumah Sakit Pusat Infeksi Sulianti Saroso,印度尼西亚雅加达。Berikut ini kami gambarkan karakteristik klinis, hasil foto thorak,概况实验室研究了terapi menggunakan favipiravir和羟氯喹seril - hroxychloroquine,用于治疗2019冠状病毒病(COVID-19)。kespulan: Kasus ini menggaribawahi bahwa pertimbangan penggunaan kegawatdaruratan抗禽流感病毒的稀松剂uji klinis pada populasen COVID-19, psien telah成员kan persetujuan dan penggunaan obat-obat - tersebut dimonitor。Kata kunci: Covid-19, favipiravir, tenaga kesehatan, laporan kasus,雅加达
{"title":"First experience of using favipiravir in the first healthcare worker patient with moderate case of Coronavirus Disease 2019 (COVID-19) at Sulianti Saroso Infectious Disease Hospital, Jakarta, Indonesia: a case report","authors":"Pompini Agustina Sitompul, N. Mariana, A. Rusli","doi":"10.22435/hsji.v12i1.4879","DOIUrl":"https://doi.org/10.22435/hsji.v12i1.4879","url":null,"abstract":"Background: During the early period of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic, there was no approved and definitive drug available for the treatment of COVID-19. Favipiravir, chloroquine, hydroxychloroquine was used for re-purposing drugs while their efficacy and safety remained a major concern for healthcare workers. Clinical trial to assess efficacy and safety were ongoing. \u0000Case presentation: We present here the case of a 38-year-old woman, the first case of a healthcare worker diagnosed with COVID-19 who had moderate type, including first experience treatment with favipiravir in Sulianti Saroso Infectious Disease Hospital, Jakarta, Indonesia. We present the clinical characteristics, chest X-ray, clinical laboratory profiles, the treatment process with favipiravir and hydroxychloroquine as well as the clinical outcome of moderate type COVID-19 patient. \u0000Conclusion: This case highlights that considering the use of emergency intervention outside of clinical trial in the COVID-19 population, the informed patient consent has been given and the use of emergency intervention was monitored. \u0000Keywords: COVID-19, favipiravir, medical worker, case report, Jakarta \u0000 \u0000Abstrak \u0000Latar belakang: Periode awal pandemi Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), belum terdapat obat yang disetujui dan pasti tersedia untuk pengobatan COVID-19. Favipiravir, chloroquine, hydroxychloroquine digunakan sebagai obat dengan indikasi baru yang sementara efektifitas dan keamanannya menjadi perhatian para petugas medis. \u0000Penyajian kasus: Disini kami melaporkan kasus wanita umur 38 tahun, merupakan kasus pertama seorang tenaga kesehatan Rumah Sakit terdiagnosis Coronavirus Disease 2019 (COVID-19) dengan penggunaan terapi favipiravir untuk pertama kalinya di Rumah Sakit Pusat Infeksi Sulianti Saroso, Jakarta, Indonesia. Berikut ini kami gambarkan karakteristik klinis, hasil foto thorak, profil laboratorium dan proses terapi menggunakan favipiravir and hidroxychloroquine serta hasil akhir pada kasus COVID-19 derajat sedang. \u0000Kesimpulan: Kasus ini menggaribawahi bahwa pertimbangan penggunaan kegawatdaruratan obat antivirus diluar uji klinis pada populasi pasien COVID-19, pasien telah memberikan persetujuan dan penggunaan obat-obat tersebut dimonitor. \u0000Kata kunci: Covid-19, favipiravir, tenaga kesehatan, laporan kasus, Jakarta","PeriodicalId":30666,"journal":{"name":"Health Science Journal of Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42356492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}