基线患者报告的结果测量是否预测了慢性疼痛康复计划后自我报告功能的变化?

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2023-12-01 Epub Date: 2023-07-31 DOI:10.1177/20494637231190190
L Heelas, A Soni, Karen Barker
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引用次数: 0

摘要

基于认知行为原则的跨学科疼痛管理方案旨在改善慢性疼痛患者的身体和心理功能,加强自我管理。目前,没有足够的证据表明心理、生物或社会因素是否能预测疼痛康复后的积极结果。本研究旨在评估临床数据集中简明疼痛清单-疼痛干扰评分(BPI)变化的预测因素,以确定年龄、性别和基线结果指标是否可以预测疼痛康复后疼痛干扰的改善。对两个疼痛康复计划,平衡生活计划(BLP)和恢复活跃计划(GBA)中常规收集的临床数据进行了回顾性、务实的观察性分析。使用标准回归和层次回归分析来确定变化的预测因素,以评估BPI的时间变化。还进行了回应者分析。对208名(BLP)和310名(GBA)患者的标准回归分析显示,较高的基线BPI和较好的身体表现指标预示着两个项目的BPI有更好的改善。分层回归显示,年龄和性别分别占BPI变化方差的2.7%(BLP)和0.002%(GBA)。在控制了年龄和性别后,其他指标解释了额外23%(BLP)和19%(GBA)的方差,p=<.001,其中BPI和身体表现指标始终是统计学上显著的预测因素,p<.05。受访者分析还显示,疼痛干扰和身体表现与改善显著相关(p=<.0005)。高自我报告的疼痛干扰和更好的身体表现测量相结合可能是衡量谁将从跨学科康复中受益的有用指标。需要对结果进行进一步验证。
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Do baseline patient reported outcome measures predict changes in self-reported function, following a chronic pain rehabilitation programme?

Background: Interdisciplinary pain management programmes, based on cognitive-behavioural principles, aim to improve physical and psychological functioning and enhance self-management in people living with chronic pain. Currently there is insufficient evidence about whether psychological, biological or social factors are predictive of positive outcomes following pain rehabilitation. This study aims to evaluate predictors of change in Brief Pain Inventory - pain interference score (BPI) in a clinical data set to determine whether age, sex and baseline outcome measures are predictive of improvement in pain interference following pain rehabilitation.

Methods: A retrospective, pragmatic observational analysis of routinely collected clinical data in two pain rehabilitation programmes, Balanced Life Programme (BLP) and Get Back Active (GBA) was conducted. Standard regression and hierarchical regression analyses were used to identify predictors of change to assess temporal changes in BPI. Responder analysis was also conducted.

Results: Standard regression analyses of 208 (BLP) and 310 (GBA) patients showed that higher baseline BPI and better physical performance measures predicted better improvement in BPI across both programmes. Hierarchical regression showed that age and sex accounted for 2.7% (BLP) and 0.002% (GBA) of the variance in change in BPI. After controlling for age and sex, the other measures explained an additional 23% (BLP) and 19% (GBA) of the variance, p = < .001 where BPI and physical performance measures were consistently statistically significant predictors, p < .05. Responder analysis also showed that pain interference and physical performance were significantly associated with improvement (p = < .0005).

Conclusions: The combination of high self-reported pain interference and better physical performance measures may be a useful indicator of who would benefit from interdisciplinary rehabilitation. Further validation of the results is required.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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