早期肠内营养促进腹腔镜直肠癌手术患者术后恢复及减少并发症

IF 0.4 4区 医学 Q4 NUTRITION & DIETETICS Current Topics in Nutraceutical Research Pub Date : 2023-07-21 DOI:10.37290/ctnr2641-452x.21:315-320
Yinzu Li, Hong Liu, Kuankuan Yang, Xiaoli Tian
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引用次数: 0

摘要

我们研究了早期肠内营养对腹腔镜直肠癌癌症手术患者术后恢复的影响以及并发症的发生率。对照组采用传统的术后营养护理,治疗组采用术后早期肠内营养。与对照组相比,治疗组术后肛门排气时间、首次排便时间、首次进食固体食物时间、肠鸣音恢复时间和住院时间更短(P<0.05),血清总蛋白、白蛋白和前白蛋白等营养相关指标升高(P<0.05)、血清炎性因子C反应蛋白、白细胞介素-6,肿瘤坏死因子-α降低(P<0.05),外周血CD3+、CD4+、CD4+/CD8+细胞升高,CD8+细胞减少(P<0.05),术后早期肠内营养不仅能促进腹腔镜直肠癌癌症手术患者的免疫功能和营养状况,而且有助于减少术后炎症反应,促进康复。
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Early Enteral Nutrition Facilitates Postoperative Recovery and Diminishes Complications in Patients Undergoing Laparoscopic Rectal Cancer Surgery
We have examined the effect of early enteral nutrition on postoperative recovery as well as the incidence of complications in patients undergoing laparoscopic rectal cancer surgery. The control group received traditional nursing care for postoperative nutrition, whereas the treatment group received early postoperative enteral nutrition. Relative to the control group, the postoperative anal exhaust time, first defecation time, first eating of solid food time, bowel sound recovery time, and hospital stay in the treatment group were shorter (P < 0.05), nutrition-related indexes including serum total protein, albumin, and prealbumin were elevated (P < 0.05), levels of serum inflammatory factors C-reactive protein, interleukin-6, and tumor necrosis factor-α were lower (P < 0.05), peripheral blood CD3+, CD4+, and CD4+/CD8+ cells were elevated, while CD8+ cells were decreased (P < 0.05). The incidence of postoperative complications in the treatment groups was lower relative to the control group (P < 0.05). To sum up, early postoperative enteral nutrition can not only promote the immune function and nutritional status of patients undergoing laparoscopic rectal cancer surgery but also help reduce the postoperative inflammatory response and promote recovery.
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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
36
审稿时长
>12 weeks
期刊介绍: Current Topics in Nutraceutical Research is an international, interdisciplinary broad-based peer reviewed scientific journal for critical evaluation of research on chemistry, biology and therapeutic applications of nutraceuticals and functional foods. The major goal of this journal is to provide peer reviewed unbiased scientific data to the decision makers in the nutraceutical and food industry to help make informed choices about development of new products. To this end, the journal will publish two types of review articles. First, a review of preclinical research data coming largely from animal, cell culture and other experimental models. Such data will provide basis for future product development and/or human research initiatives. Second, a critical evaluation of current human experimental data to help market and deliver the product for medically proven use. This journal will also serve as a forum for nutritionists, internists, neurologists, psychiatrists, and all those interested in preventive medicine. The common denominator of all of the topic to be covered by the journal must include nutraceuticals and/functional food. The following is an example of some specific areas that may be of interest to the journal. i) Role of vitamins, minerals, antioxidants and phytonutrients on cardiovascular health, cancer, diabetes, ocular health, mental health, men’s health, women’s health, infant nutrition, ii) Role of herbals on human health, iii) Dietary supplements and sleep, iv) Components of diet that may have beneficial effect on human health, v) regulation of apoptosis and cell viability, vi) Isolation and characterization of bioactive components from functional foods, vii) Nutritional genomics, and viii) Nutritional proteomics.
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