在老年人中开发一种简短的抑郁症筛查工具

IF 1.7 4区 医学 Q3 GERIATRICS & GERONTOLOGY Psychogeriatrics Pub Date : 2022-05-07 DOI:10.1111/psyg.12846
P. Soysal, L. Smith
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引用次数: 0

摘要

尊敬的编辑:我们怀着极大的兴趣阅读了刚刚发表在贵刊上的Gokcekuyu等人的研究。在这项研究中,作者的目的是在土耳其老年人群中验证一个包含五个问题的老年抑郁量表(GDS-5),但实际上GDS-5之前在土耳其被Dokuzlar等人重新验证过。Gokcekuyu等人的研究似乎很有价值;然而,在验证用于筛查的简短量表时,需要考虑到一些方法学上的考虑。与本研究一样,Dokuzlar等人的目的是验证土耳其老年患者的GDS-4和GDS-5,两项研究都纳入了老年诊所的门诊患者。然而,由于这些研究是在土耳其两个不同的社会文化区域进行的,GDS-5的敏感性较高(96.4%对85.8%),特异性较低(67.7%对92.1%),这取决于参与者的教育水平差异。然而,两项研究的重要共同发现是Cronbach 's α值低于0.7,即内部一致性系数处于可疑水平,这意味着GDS-5或其部分项目不能代表抑郁症受访者。为了解决这个问题,通过执行Kappa一致性分析,可以检查GDS长格式中每个项目的评级间可靠性,并且可以使用具有最高Kappa值的项目生成特定于社区的短格式。为了保证土耳其GDS-5 (TGDS-5)的有效性,我们也应用了该方法。因此,我们发现TGDS-5和最初的GDS-5只有一个共同点(“你经常感到无聊吗?”)。其他项目与GDS-5不同;而TGDS-5的Cronbach ' s α值为0.807,即内部一致性系数为“良好”。在我们的研究中,虽然gds -5的特异性和阳性预测值(PPV)很高,但其敏感性值明显较低,作为筛选工具的低敏感性值限制了其使用。由于上述缺陷和GDS-5的低内部一致性(根据Cronbach 's α分析),在土耳其老年人中使用GDS-5并不合适。由于短TGDS-5的敏感性和阴性预测值高于其特异性和PPV,因此TGDS-5在排除抑郁症方面比诊断抑郁症更有效。因此,TGDS-5可能在日常实践中作为第一阶段筛查试验有用。因此,Gokcekuyu等人的研究对文献的贡献是显著的。然而,根据每个人的社会文化特点,为他们制定适当的量表似乎是有益的。因此,tgds -5可能比GDS-5更适合土耳其老年人的抑郁症测试。
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The development of a short depression screening tool in older adults
Dear Editor, We read with great interest the study of Gokcekuyu et al., which has just been published in your journal. In this study, the authors aimed to validate a fivequestion version of the Geriatric Depression Scale (GDS-5) in the elderly Turkish population, but actually the GDS-5 was previously revalidated in Turkish by Dokuzlar et al. The study of Gokcekuyu et al. seems valuable; however, some methodological considerations need to be taken into account when validating the short forms of scales used for screening. Just like in this study, Dokuzlar et al.’s aimed to validate the GDS-4 and GDS-5 in Turkish elderly patients, and outpatients to geriatric clinics were included in both studies. However, due to the fact that these studies were conducted in two different sociocultural regions of Turkey, the sensitivity of the GDS-5 was higher (96.4% vs 85.8%) and the specificity was lower (67.7% vs 92.1%) depending on the differences in the education levels of the participants. However, the important finding common to both studies is that the Cronbach’s α value is below 0.7, that is, the internal consistency coefficient is at a questionable level, which means that the GDS-5 or some of its items do not represent respondents with depression. To solve this problem, by performing Kappa consistency analysis, the inter-rater reliability of each of the items in the long form of the GDS can be checked, and community-specific short forms can be produced with those items having the highest kappa values.We also applied thismethod to ensure the validity in developing the Turkish GDS-5 (TGDS-5). Thus, we found that the TGDS-5 and the original GDS-5 have only one common item (‘Do you often get bored?’). Other items differed from the GDS-5; however, the Cronbach’s α of the TGDS-5 increased to 0.807, that is, the internal consistency coefficient was ‘good’. In our study, although the specificity and positive predictive value (PPV) of theGDS-5were high, its sensitivity valuewas significantly lower, and low a sensitivity value ​​for a screening tool limits its use. Due to the mentioned drawbacks and the low internal consistency of the GDS-5 (according to the Cronbach’s α analysis), the use of the GDS-5 in Turkish older adults is not appropriate. Since the sensitivity and negative predictive values of the short TGDS-5 are higher than its specificity and PPV, the TGDS-5 is more effective for excluding depression rather than for diagnosing depression. Thus, the TGDS-5 may be useful as a first-stage screening test in a daily practice. As a result, the contribution of Gokcekuyu et al.’s study to the literature is significant. However, it seems to be beneficial to develop appropriate scales for each population, according to their sociocultural characteristics. Thus, the TGDS-5might be amore appropriate test for depression in the Turkish elderly than the GDS-5.
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来源期刊
Psychogeriatrics
Psychogeriatrics Medicine-Geriatrics and Gerontology
CiteScore
3.60
自引率
5.00%
发文量
115
审稿时长
>12 weeks
期刊介绍: Psychogeriatrics is an international journal sponsored by the Japanese Psychogeriatric Society and publishes peer-reviewed original papers dealing with all aspects of psychogeriatrics and related fields The Journal encourages articles with gerontopsychiatric, neurobiological, genetic, diagnostic, social-psychiatric, health-political, psychological or psychotherapeutic content. Themes can be illuminated through basic science, clinical (human and animal) studies, case studies, epidemiological or humanistic research
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