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Longitudinal relationship between loneliness and cognitive function among unmarried older adults in Malaysia: exploring gender disparities 马来西亚未婚老年人的孤独感与认知功能之间的纵向关系:探索性别差异
IF 2 4区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2024-09-18 DOI: 10.1111/psyg.13196
Hui Foh Foong, Rahimah Ibrahim, Siti Farra Zillah Abdullah, Mohamad Fazdillah Bagat
BackgroundThe status of being unmarried is commonly associated with a higher tendency for loneliness and cognitive impairment. However, it has yet to be determined whether there is a link between loneliness and cognitive function among unmarried older people. Therefore, this study used longitudinal data to determine the link between loneliness and cognitive function, and the subjects were unmarried community‐dwelling older adults.MethodsThe study follows up a sample of 733 unmarried older adults who were either never married, widowed, divorced or separated, from waves one and two of the ‘Neuroprotective Model for Healthy Longevity among Malaysian Older Adults’ study. The main statistical analysis used to answer the research question was the PROCESS macro (model 1) for SPSS.ResultsThe study found that increased loneliness was associated with a decline in cognitive function over a 3‐year period. Additionally, gender moderated the link between loneliness and cognitive function, with this association being particularly prominent in older men.ConclusionsLoneliness among unmarried older people should be given attention as it could lead to deteriorating cognitive function. Notably, older men experience a more substantial impact of loneliness on cognitive function than women. Therefore, special attention should be focused on this population, and more social services should be developed to reduce the incidence of cognitive impairment, improve their quality of life, and promote successful ageing.
背景未婚通常与较高的孤独感和认知障碍倾向有关。然而,未婚老年人的孤独感与认知功能之间是否存在联系尚待确定。因此,本研究使用纵向数据来确定孤独感与认知功能之间的联系,研究对象为居住在社区的未婚老年人。方法本研究对 "马来西亚老年人健康长寿神经保护模式 "研究第一和第二波中的 733 名未婚老年人进行了跟踪调查,这些老年人要么从未结过婚,要么丧偶、离婚或分居。研究发现,孤独感的增加与 3 年认知功能的下降有关。结论未婚老年人的孤独感可能导致认知功能下降,因此应引起重视。值得注意的是,与女性相比,老年男性的孤独感对认知功能的影响更大。因此,应特别关注这一人群,并提供更多的社会服务,以减少认知障碍的发生率,改善他们的生活质量,促进成功老龄化。
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引用次数: 0
Low‐dose lamotrigine induces Pisa syndrome in a patient with probable corticobasal degeneration despite previous use 小剂量拉莫三嗪会诱发一名可能患有皮质基底层变性的患者出现比萨综合征,尽管他以前使用过这种药物
IF 2 4区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2024-09-17 DOI: 10.1111/psyg.13195
Naomichi Okamoto, Takahiro Sakakibara, Nagiho Tsukada, Enkhmurun Chibaatar, Gaku Hayasaki, Yuki Konishi, Atsuko Ikenouchi, Reiji Yoshimura
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引用次数: 0
Reply to ‘The clinical application value of psychological nursing intervention for patients with prostatic hyperplasia during treatment’ 回复:"前列腺增生患者治疗期间心理护理干预的临床应用价值
IF 2 4区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2024-09-15 DOI: 10.1111/psyg.13193
Kohei Kajiwara, Jun Kako, Masamitsu Kobayashi, Yasuhide Etou, Teppei Yamashita, Makoto Yamanaka
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引用次数: 0
Beyond the stethoscope: ageism in white coats and resident physicians' preferences for elderly patient care 听诊器之外:白大褂上的年龄歧视和住院医生对老年患者护理的偏好
IF 2 4区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2024-09-12 DOI: 10.1111/psyg.13192
Süleyman Utku Uzun, Merve Akın
BackgroundThe global increase in life expectancy has significantly raised the elderly population. In Türkiye, the proportion of individuals aged 65 and over rose from 8.8% in 2018 to 10.2% in 2023. This demographic shift necessitates the planning of social and health services for the elderly. Ageism affects elderly health negatively and is prevalent in healthcare settings. This study aimed to determine the prevalence of ageism among resident physicians at Pamukkale University Hospital and identify factors influencing their preferences for providing healthcare to elderly patients.MethodsThis cross‐sectional study was conducted at Pamukkale University Hospital between 6 June and 16 June, 2024. A total of 448 resident physicians were selected through simple random sampling. Data were collected using a self‐administered questionnaire, which included sociodemographic information, factors affecting ageism, and the Fraboni Scale of Ageism (FSA). Descriptive statistics, Chi‐square tests, and logistic regression were used to evaluate factors influencing healthcare preferences.ResultsThe FSA score averaged 71.89 ± 7.87, indicating a 20.1% (95% CI:16.48–24.10) prevalence of age discrimination among resident physicians. Logistic regression analysis revealed that male participants (odds ratio (OR) = 1.519, P = 0.042), those with moderate to very poor perceived knowledge of elderly health (OR = 2.418, P < 0.001), and higher FSA scores (OR = 1.046, P < 0.001) were more likely to prefer not providing healthcare services to elderly patients.ConclusionsAgeism among resident physicians is prevalent, impacting their willingness to provide care to elderly patients. Gender, perceived knowledge, and ageist attitudes influence their preferences for providing healthcare to elderly patients. Addressing these factors is crucial for improving healthcare services for the elderly.
背景全球预期寿命的延长大大增加了老年人口。在土耳其,65 岁及以上人口的比例将从 2018 年的 8.8%增至 2023 年的 10.2%。这种人口结构的变化要求我们必须为老年人规划社会和医疗服务。老龄歧视会对老年人的健康产生负面影响,在医疗机构中普遍存在。本研究旨在确定帕慕卡莱大学医院住院医师中普遍存在的老龄歧视现象,并找出影响他们为老年患者提供医疗服务的偏好的因素。通过简单随机抽样,共选取了 448 名住院医师。研究采用自填式问卷收集数据,其中包括社会人口学信息、影响老龄歧视的因素以及弗拉博尼老龄歧视量表(FSA)。结果FSA得分平均为71.89 ± 7.87,表明住院医师中年龄歧视的发生率为20.1% (95% CI:16.48-24.10) 。逻辑回归分析表明,男性参与者(几率比(OR)= 1.519,P = 0.042)、老年健康知识认知度中等至非常差者(OR = 2.418,P <0.001)和 FSA 分数较高者(OR = 1.046,P <0.001)更倾向于不为老年患者提供医疗服务。性别、认知知识和年龄歧视态度影响了他们为老年患者提供医疗服务的偏好。解决这些因素对于改善老年医疗服务至关重要。
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引用次数: 0
Validity and reliability of the Checklist for Habitual Physical Activity for people 75 years and older in Japan 日本 75 岁及以上老年人习惯性体育活动核对表的有效性和可靠性
IF 2 4区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2024-09-10 DOI: 10.1111/psyg.13189
Kuniko Arita, Yu Ishibashi, Takayuki Tajima, Yoshiaki Ikechi, Hitomi Ishibashi
BackgroundDespite health benefits, many older adults struggle to meet physical activity guidelines, leading to stagnant activity levels. While integrating physical activity into daily routines has been proposed as a promising strategy for older adults, fit‐for‐purpose measurement tools to assess such routines are lacking. The Checklist for Habitual Physical Activity (CHaPA) was developed based on the positive deviance approach and socio‐ecological model to assess daily behaviours encouraging physical activity among adults aged 75 and older. It has been confirmed for its content and face validity. However, to ensure its broader applicability and usefulness, assessing its construct validity and reliability is necessary. Therefore, this study aims to assess the construct validity and reliability of the CHaPA and accordingly update the tool.MethodsTo validate the construct validity of the CHaPA 22‐item version, we conducted item analysis and exploratory and confirmatory factor analyses. We removed inappropriate items based on predefined criteria. Then, we assessed the reliability, internal consistency, test–retest reliability, and measurement errors of the CHaPA final version.ResultsItem analyses and factor analyses resulted in the deletion of 11 items. The results of confirmatory factor analysis validated the CHaPA 11‐item version with the three‐factor structure based on model fit index with χ2/degree of freedom = 1.25, comparative fit index = 0.965, Tucker‐Lewis index = 0.952, and root‐mean‐square error of approximation = 0.038. Omega coefficient (0.90) showed excellent internal consistency. Intraclass correlation coefficient (ICC) demonstrated good test–retest reliability (ICC (1, 2) = 0.77, 95% CI = 0.34–0.89, standard error of measurement = 1.75).ConclusionsWe finalised the CHaPA 11‐item version as a valid and reliable instrument for assessing daily behaviours conducive to physical activity among individuals aged 75 years and older. We need to examine the methods and effectiveness of disseminating this checklist to ensure its utilisation as a resource for promoting healthy ageing and aiding older adults in maintaining active lifestyles.
背景尽管体育锻炼对健康有益,但许多老年人仍难以达到体育锻炼指南的要求,导致活动量停滞不前。虽然将体育锻炼融入日常生活已被认为是老年人的一项有前途的策略,但目前还缺乏适合的测量工具来评估这种日常生活。习惯性体育锻炼检查表(CHaPA)是根据积极偏差法和社会生态模型开发的,用于评估 75 岁及以上老年人鼓励体育锻炼的日常行为。其内容和表面效度已得到确认。然而,为确保其更广泛的适用性和实用性,有必要对其构造效度和信度进行评估。因此,本研究旨在评估 CHaPA 的建构效度和信度,并据此更新该工具。方法为了验证 CHaPA 22 个项目版本的建构效度,我们进行了项目分析以及探索性和确认性因子分析。我们根据预先设定的标准删除了不合适的项目。然后,我们评估了 CHaPA 最终版本的信度、内部一致性、重测信度和测量误差。根据模型拟合指数(χ2/自由度 = 1.25)、比较拟合指数 = 0.965、Tucker-Lewis 指数 = 0.952 和均方根近似误差 = 0.038,确认性因素分析的结果验证了 CHaPA 11 个项目的三因素结构。欧米茄系数(0.90)显示出极好的内部一致性。类内相关系数(ICC)显示了良好的测试-再测可靠性(ICC (1, 2) = 0.77, 95% CI = 0.34-0.89,测量标准误差 = 1.75)。结论我们最终确定了 CHaPA 11 个项目的版本,它是评估 75 岁及以上老年人有利于体育锻炼的日常行为的有效、可靠的工具。我们需要研究推广该核对表的方法和效果,以确保其成为促进健康老龄化和帮助老年人保持积极生活方式的资源。
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引用次数: 0
Prevalence and factors associated with probable depression among the oldest old during the Covid‐19 pandemic: evidence from the large, nationally representative ‘Old Age in Germany (D80+)’ study Covid-19 大流行期间最年长者中抑郁症的患病率和相关因素:来自大型、具有全国代表性的 "德国老年(D80+)"研究的证据
IF 2 4区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2024-05-03 DOI: 10.1111/psyg.13129
André Hajek, Hans‐Helmut König, Angelina R. Sutin, Antonio Terracciano, Martina Luchetti, Yannick Stephan, Razak M. Gyasi
BackgroundTo date, most studies examining the prevalence and determinants of depression among individuals aged 80 and over have used geographically limited samples that are not generalisable to the wider population. Thus, our aim was to identify the prevalence and the factors associated with probable depression among the oldest old in Germany based on nationally representative data.MethodsData were taken from the nationally representative ‘Old Age in Germany (D80+)’ study (n = 8386; November 2020 to April 2021) covering both community‐dwelling and institutionalised individuals aged 80 and over. The Short Form of the Depression in Old Age Scale was used to quantify probable depression.ResultsProbable depression was found in 40.7% (95% CI: 39.5% to 42.0%) of the sample; 31.3% were men (95% CI: 29.7% to 32.9%) and 46.6% women (95% CI: 44.9% to 48.3%). The odds of probable depression were positively associated with being female (odds ratio (OR): 1.55, 95% CI: 1.30 to 1.84), being divorced (compared to being married, OR: 1.33, 95% CI: 1.01 to 1.76), being widowed (OR: 1.14, 95% CI: 1.00 to 1.30), having a low education (e.g., medium education compared to low education, OR: 0.86, 95% CI: 0.74 to 0.99), living in an institutionalised setting (OR: 2.36, 95% CI: 1.84 to 3.02), living in East Germany (OR: 1.21, 95% CI, 1.05 to 1.39), not having German citizenship (German citizenship compared to other citizenship, OR: 0.55, 95% CI: 0.31 to 0.95), poor self‐rated health (OR: 0.31, 95% CI: 0.28 to 0.34), and the number of chronic conditions (OR: 1.12, 95% CI: 1.09 to 1.14).ConclusionAbout four out of 10 individuals aged 80 and over in Germany had probable depression, underlining the importance of this challenge. Knowledge of specific risk factors for this age group may assist in addressing older adults at risk of probable depression.
背景迄今为止,大多数针对 80 岁及以上老年人抑郁症患病率和决定因素的研究都使用了受地域限制的样本,无法推广到更广泛的人群中。因此,我们的目的是根据具有全国代表性的数据,确定德国最年长者中抑郁症的患病率及其相关因素。方法数据来自具有全国代表性的 "德国老年(D80+)"研究(n = 8386;2020 年 11 月至 2021 年 4 月),涵盖 80 岁及以上的社区居住者和机构居住者。结果40.7%(95% CI:39.5% 至 42.0%)的样本发现可能患有抑郁症,其中男性占 31.3%(95% CI:29.7% 至 32.9%),女性占 46.6%(95% CI:44.9% 至 48.3%)。可能患抑郁症的几率与女性(几率比 (OR):1.55,95% CI:1.30 至 1.84)、离婚(与已婚相比,OR:1.33,95% CI:1.01 至 1.76)、丧偶(OR:1.14,95% CI:1.00 至 1.30)、教育程度低(例如,中等教育与低教育相比,OR:1.00 至 1.30)呈正相关、中等教育与低教育相比,OR:0.86,95% CI:0.74 至 0.99),生活在机构环境中(OR:2.36,95% CI:1.84 至 3.02),生活在东德(OR:1.21,95% CI:1.05 至 1.39),没有德国国籍(德国国籍与其他国籍相比,OR:0.结论在德国,每 10 位 80 岁及以上的老人中,约有 4 位可能患有抑郁症,这凸显了这一挑战的重要性。了解这一年龄组的特定风险因素有助于解决老年人可能患有抑郁症的问题。
{"title":"Prevalence and factors associated with probable depression among the oldest old during the Covid‐19 pandemic: evidence from the large, nationally representative ‘Old Age in Germany (D80+)’ study","authors":"André Hajek, Hans‐Helmut König, Angelina R. Sutin, Antonio Terracciano, Martina Luchetti, Yannick Stephan, Razak M. Gyasi","doi":"10.1111/psyg.13129","DOIUrl":"https://doi.org/10.1111/psyg.13129","url":null,"abstract":"BackgroundTo date, most studies examining the prevalence and determinants of depression among individuals aged 80 and over have used geographically limited samples that are not generalisable to the wider population. Thus, our aim was to identify the prevalence and the factors associated with probable depression among the oldest old in Germany based on nationally representative data.MethodsData were taken from the nationally representative ‘Old Age in Germany (D80+)’ study (<jats:italic>n</jats:italic> = 8386; November 2020 to April 2021) covering both community‐dwelling and institutionalised individuals aged 80 and over. The Short Form of the Depression in Old Age Scale was used to quantify probable depression.ResultsProbable depression was found in 40.7% (95% CI: 39.5% to 42.0%) of the sample; 31.3% were men (95% CI: 29.7% to 32.9%) and 46.6% women (95% CI: 44.9% to 48.3%). The odds of probable depression were positively associated with being female (odds ratio (OR): 1.55, 95% CI: 1.30 to 1.84), being divorced (compared to being married, OR: 1.33, 95% CI: 1.01 to 1.76), being widowed (OR: 1.14, 95% CI: 1.00 to 1.30), having a low education (e.g., medium education compared to low education, OR: 0.86, 95% CI: 0.74 to 0.99), living in an institutionalised setting (OR: 2.36, 95% CI: 1.84 to 3.02), living in East Germany (OR: 1.21, 95% CI, 1.05 to 1.39), not having German citizenship (German citizenship compared to other citizenship, OR: 0.55, 95% CI: 0.31 to 0.95), poor self‐rated health (OR: 0.31, 95% CI: 0.28 to 0.34), and the number of chronic conditions (OR: 1.12, 95% CI: 1.09 to 1.14).ConclusionAbout four out of 10 individuals aged 80 and over in Germany had probable depression, underlining the importance of this challenge. Knowledge of specific risk factors for this age group may assist in addressing older adults at risk of probable depression.","PeriodicalId":20784,"journal":{"name":"Psychogeriatrics","volume":"4 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140836564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alterations in driving ability and their relationship with morphometric magnetic resonance imaging indicators in patients with amnestic mild cognitive impairment and Alzheimer's disease 失忆性轻度认知障碍和阿尔茨海默病患者驾驶能力的变化及其与形态计量磁共振成像指标的关系
IF 2 4区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2024-05-01 DOI: 10.1111/psyg.13128
Hideaki Wakita, Yu Takahashi, Satoshi Masuzugawa, Hiroyuki Miyasaka, Shigeru Sonoda, Akihiro Shindo, Hidekazu Tomimoto
BackgroundDrivers with dementia are at a higher risk of motor vehicle accidents. The characteristics of driving behaviour of patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD) have not been fully elucidated. We investigated driving ability and its relationship with cognitive function and magnetic resonance imaging (MRI) morphometry indicators.MethodsThe driving abilities of 19 patients with AD and 11 with amnestic MCI (aMCI) were evaluated using a driving simulator. The association between each driving ability parameter and the Mini‐Mental State Examination (MMSE) score or voxel‐based specific regional analysis system for AD (VSRAD) was assessed.ResultsPatients with AD made a significantly higher number of operational errors than those with aMCI in attention allocation in the complex task test (P = 0.0008). The number of operational errors in attention allocation in the complex task test significantly and negatively correlated with MMSE scores in all participants (r = −0.4354, P = 0.0162). The decision time in the selective reaction test significantly and positively correlated with the severity and extent of medial temporal structural atrophy (r = 0.4807, P = 0.0372; r = 0.4862, P = 0.0348; respectively).ConclusionAn increase in the operational errors for attention allocation in the complex task test could be a potential indicator of progression from aMCI to AD. Atrophy of the medial temporal structures could be a potential predictor of impaired judgement in driving performance in aMCI and AD. A driving simulator could be useful for evaluating the driving abilities of individuals with aMCI and AD.
背景痴呆症患者发生车祸的风险较高。轻度认知障碍(MCI)和阿尔茨海默病(AD)患者的驾驶行为特征尚未完全阐明。我们对驾驶能力及其与认知功能和磁共振成像(MRI)形态指标的关系进行了研究。结果在复杂任务测试中,AD 患者在注意力分配方面的操作失误次数明显高于 aMCI 患者(P = 0.0008)。在复杂任务测试中,注意力分配的操作失误次数与所有参与者的MMSE评分呈显著负相关(r = -0.4354,P = 0.0162)。选择性反应测试中的决策时间与颞叶内侧结构萎缩的严重程度和范围呈显著正相关(分别为 r = 0.4807,P = 0.0372;r = 0.4862,P = 0.0348)。颞叶内侧结构的萎缩可能是 aMCI 和 AD 患者驾驶能力判断受损的潜在预测因素。驾驶模拟器可用于评估aMCI和AD患者的驾驶能力。
{"title":"Alterations in driving ability and their relationship with morphometric magnetic resonance imaging indicators in patients with amnestic mild cognitive impairment and Alzheimer's disease","authors":"Hideaki Wakita, Yu Takahashi, Satoshi Masuzugawa, Hiroyuki Miyasaka, Shigeru Sonoda, Akihiro Shindo, Hidekazu Tomimoto","doi":"10.1111/psyg.13128","DOIUrl":"https://doi.org/10.1111/psyg.13128","url":null,"abstract":"BackgroundDrivers with dementia are at a higher risk of motor vehicle accidents. The characteristics of driving behaviour of patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD) have not been fully elucidated. We investigated driving ability and its relationship with cognitive function and magnetic resonance imaging (MRI) morphometry indicators.MethodsThe driving abilities of 19 patients with AD and 11 with amnestic MCI (aMCI) were evaluated using a driving simulator. The association between each driving ability parameter and the Mini‐Mental State Examination (MMSE) score or voxel‐based specific regional analysis system for AD (VSRAD) was assessed.ResultsPatients with AD made a significantly higher number of operational errors than those with aMCI in attention allocation in the complex task test (<jats:italic>P</jats:italic> = 0.0008). The number of operational errors in attention allocation in the complex task test significantly and negatively correlated with MMSE scores in all participants (<jats:italic>r</jats:italic> = −0.4354, <jats:italic>P</jats:italic> = 0.0162). The decision time in the selective reaction test significantly and positively correlated with the severity and extent of medial temporal structural atrophy (<jats:italic>r</jats:italic> = 0.4807, <jats:italic>P</jats:italic> = 0.0372; <jats:italic>r</jats:italic> = 0.4862, <jats:italic>P</jats:italic> = 0.0348; respectively).ConclusionAn increase in the operational errors for attention allocation in the complex task test could be a potential indicator of progression from aMCI to AD. Atrophy of the medial temporal structures could be a potential predictor of impaired judgement in driving performance in aMCI and AD. A driving simulator could be useful for evaluating the driving abilities of individuals with aMCI and AD.","PeriodicalId":20784,"journal":{"name":"Psychogeriatrics","volume":"11 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140836629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The treatment of behavioural and psychological symptoms in dementia: pragmatic recommendations 痴呆症患者行为和心理症状的治疗:实用建议
IF 2 4区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2024-04-19 DOI: 10.1111/psyg.13116
Camille Mercier, Victoria Rollason, Mohamed Eshmawey, Aline Mendes, Giovanni B. Frisoni
Behavioural and psychological symptoms of dementia (BPSD) are a clinical challenge for the lack of a sound taxonomy, frequent presentation with comorbid BPSD, lack of specific pharmacologic interventions, poor base of methodologically sound evidence with randomized clinical trials, contamination from the treatment of behavioural disturbances of young and adult psychiatric conditions, and small efficacy window of psychotropic drugs. We present here a treatment workflow based on a concept‐driven literature review based on the notions that (i) the aetiology of BPSD can be mainly neurobiological (so‐called ‘primary’ symptoms) or mainly environmental and functional (‘secondary’ symptoms) and that this drives treatment; (ii) the clinical efficacy of psychotropic drugs is driven by their specific profile of receptor affinity; (iii) drug treatment should follow the rules of ‘start low–go slow, prescribe and revise’. This article argues in support of the distinction between primary and secondary BPSD, as well as their characteristics, which until now have been just sketchily described in the literature. It also offers comprehensive and pragmatic clinician‐oriented recommendations for the treatment of BPSD.
痴呆症的行为和心理症状(BPSD)是一项临床挑战,因为它缺乏完善的分类标准,经常与 BPSD 合并出现,缺乏特定的药物干预措施,随机临床试验的方法学证据基础薄弱,与治疗青少年和成人精神疾病的行为障碍有冲突,精神药物的疗效窗口较小。我们在此基于概念驱动的文献综述,提出了一套治疗工作流程,该流程基于以下概念:(i) BPSD 的病因可能主要是神经生物学方面的(所谓的 "原发性 "症状),也可能主要是环境和功能方面的("继发性 "症状),而这正是治疗的驱动因素;(ii) 精神药物的临床疗效受其受体亲和力的特定特征驱动;(iii) 药物治疗应遵循 "低剂量开始、缓慢进行、处方和修正 "的规则。本文论证了原发性和继发性 BPSD 之间的区别及其特征,迄今为止,文献中对这些区别和特征的描述还很粗略。文章还为临床医生治疗 BPSD 提供了全面、务实的建议。
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引用次数: 0
Cognitive behavioural therapy for depression, quality of life, and cognitive function in the post‐stroke period: systematic review and meta‐analysis 针对中风后抑郁、生活质量和认知功能的认知行为疗法:系统回顾和荟萃分析
IF 2 4区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2024-04-18 DOI: 10.1111/psyg.13125
Mingye Wan, Ying Zhang, Youping Wu, Xia Ma
The post‐stroke period is associated with a lot of sequelae, including depression, decreased quality of life, and decline of cognitive function. Apart from the pharmacotherapy, it is also important to find a non‐pharmacological treatment to relieve the sequelae. Cognitive behavioural therapy (CBT) might be a potential candidate, which can be clarified by a systematic review and meta‐analysis. The eligible criteria of enrolled studies in the systematic review and meta‐analysis were the randomised clinical trials (RCTs) using CBT to treat post‐stroke depression, or with the focus on quality of life or cognitive function in the post‐stroke period. The endpoint scores of depression, quality of life, and cognitive function scales were the targeted outcome for the final meta‐analysis in the random effects model. Ten RCTs with 432 post‐stroke patients receiving CBT and 385 controls were included. The meta‐analysis results showed significant improvements in depression severity and quality of life. However, no significant difference between CBT and control groups was found in cognitive function. In addition, significant heterogeneity was derived from the meta‐analysis. According to the meta‐analysis results, CBT might be beneficial for relieving depression severity and improving quality of life. However, cognitive function might not be influenced by CBT. Further studies with a more consistent CBT design with greater sample sizes should be warranted to clarify and confirm the treatment effects of CBT for post‐stroke depression and quality of life.
中风后遗症很多,包括抑郁、生活质量下降和认知功能减退。除了药物治疗外,寻找一种非药物治疗方法来缓解后遗症也很重要。认知行为疗法(CBT)可能是一种潜在的候选疗法,可通过系统回顾和荟萃分析加以明确。系统综述和荟萃分析中的入选研究的合格标准是使用 CBT 治疗中风后抑郁,或侧重于中风后生活质量或认知功能的随机临床试验(RCT)。在随机效应模型中,抑郁、生活质量和认知功能量表的终点评分是最终荟萃分析的目标结果。共纳入了 10 项研究,包括 432 名接受 CBT 治疗的脑卒中后患者和 385 名对照组患者。荟萃分析结果显示,抑郁严重程度和生活质量均有显著改善。然而,CBT 组和对照组在认知功能方面没有发现明显差异。此外,荟萃分析还发现了明显的异质性。根据荟萃分析结果,CBT 可能对缓解抑郁严重程度和改善生活质量有益。然而,认知功能可能不受 CBT 的影响。为了澄清和确认 CBT 对卒中后抑郁和生活质量的治疗效果,有必要进一步开展样本量更大、设计更一致的 CBT 研究。
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引用次数: 0
The effectiveness of a fall detection device in older nursing home residents: a pilot study 养老院老年居民跌倒检测装置的有效性:一项试点研究
IF 2 4区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2024-04-18 DOI: 10.1111/psyg.13126
Büşra Can, Aslı Tufan, Şevval Karadağ, Nurdan Şentürk Durmuş, Mümüne Topçu, Berrin Aysevinç, Songül Çeçen Düzel, Sevda Dağcıoğlu, Nazire Afşar Fak, Gökhan Tazegül, Ali Serdar Fak
BackgroundReal‐world research to evaluate the effect of device technology in preventing fall‐related morbidity is limited. This pilot study aims to investigate the effectiveness of a non‐wearable fall detection device in older nursing home residents.MethodsThe study was conducted in a nursing home with single‐resident rooms. Fall detection devices were randomly set up in half of the rooms. Demographic data, comorbidities, lists of medications, and functional, nutritional, and frailty status were recorded. The residents were followed up for 3 months. The primary outcome was falls and the secondary outcome was all‐cause mortality.ResultsA total of 26 participants were enrolled in the study. The study group consisted of 13 residents who had a fall detection device in their rooms. The remaining 13 residents on the same floor formed the control group. Participants had a mean age of 82 ± 10 years and 89% of the residents were female. The most prevalent comorbidity was dementia. Two residents from the control group and one resident from the study group experienced a fall event during follow‐up. The fall events in the control group were identified retrospectively by the nursing home staff, whereas the fall in the study group received a prompt response from the staff who were notified by the alarm. One resident was transferred to the hospital and died due to a non‐fall related reason.ConclusionDevice technology may provide an opportunity for timely intervention to prevent fall‐related morbidity in institutionalized older adults.
背景评估设备技术在预防跌倒相关发病率方面效果的实际研究非常有限。本试验研究旨在调查非穿戴式跌倒检测装置对老年疗养院居民的有效性。在一半的房间中随机安装了跌倒检测装置。记录人口统计学数据、合并症、药物清单以及功能、营养和虚弱状况。对住户进行了为期 3 个月的随访。主要结果是跌倒,次要结果是全因死亡率。研究组包括 13 名在房间内安装了跌倒检测装置的居民。同一楼层的其余 13 位居民组成对照组。参与者的平均年龄为 82 ± 10 岁,89% 的居民为女性。最常见的合并症是痴呆症。在随访期间,对照组和研究组分别有两名和一名居民发生了跌倒事件。对照组中的跌倒事件是由疗养院工作人员事后发现的,而研究组中的跌倒事件则是由接到警报通知的工作人员及时处理的。结论:设备技术可以提供及时干预的机会,预防养老院中老年人与跌倒相关的发病率。
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Psychogeriatrics
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