加拿大安大略省1型糖尿病儿童和青少年血糖管理中公共资助药物和社会经济差异的介绍:基于人群的趋势分析

CMAJ open Pub Date : 2022-04-01 DOI:10.9778/cmajo.20210214
M. Giruparajah, K. Everett, B. Shah, P. Austin, Shai Fuchs, Rayzel Shulman
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引用次数: 0

摘要

背景:我们评估了2018年1月1日在安大略省推出的针对25岁以下青年的公共资助药物(安大略省健康保险计划[OHIP]+)对血红蛋白A1c(HbA1c,一种血糖管理指标)时间趋势的影响,以及根据社会经济地位(SES)对HbA1c时间趋势变化的差异影响。方法:我们使用管理数据集进行趋势分析。我们包括2016年1月1日居住在安大略省的21岁、9个月或以下的年轻人,他们在15岁之前和2015年1月一日之前被诊断为糖尿病。我们使用胰岛素的声明来衡量药物的使用。我们使用分段回归分析评估了在引入OHIP+覆盖之前(2016年1月1日至2017年12月31日)和期间(2018年4月1日和2019年3月31日期间)每90天HbA1c(%)的变化,以及根据SES的HbA1c变化的差异。结果:9641例患者中,7041例(73.0%)提出了胰岛素需求。我们发现,与OHIP+覆盖前相比,覆盖期间HbA1c的时间变化差异可忽略不计,无统计学意义(β估计值−0.0002,95%置信区间[CI]−0.0004至0.0000)。SES最低的个体的影响程度略大于SES最高的个体(β估计数−0.0008,95%CI−0.0015至−0.0001)。解释:我们发现,在社会经济地位最低的青年中,OHIP+对HbA1c变化的影响略大于社会经济地位最高的青年。我们的研究结果表明,公共资助的药物可能是一种有效的政策工具,可以对抗糖尿病护理和结果方面日益恶化的社会经济差异。
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Introduction of publicly funded pharmacare and socioeconomic disparities in glycemic management in children and youth with type 1 diabetes in Ontario, Canada: a population-based trend analysis
Background: We evaluated the impact of publicly funded pharmacare (Ontario Health Insurance Plan [OHIP]+), which was introduced in Ontario on Jan. 1, 2018, for youth less than 25 years of age, on temporal trends in hemoglobin A1c (HbA1c, a measure of glycemic management) and the differential effect on the change in temporal trends in HbA1c according to socioeconomic status (SES). Methods: We conducted a trend analysis using administrative data sets. We included youth aged 21 years, 9 months or younger, residing in Ontario on Jan. 1, 2016, with diabetes diagnosed before age 15 years and before Jan. 1, 2015. We used claims for insulin to measure pharmacare use. We evaluated the change in HbA1c (%) per 90 days before (Jan. 1, 2016, to Dec. 31, 2017) the introduction of and during (Apr. 1, 2018, to Mar. 31, 2019) OHIP+ coverage, and the difference in the change in HbA1c according to SES, using segmented regression analysis. Results: Of 9641 patients, 7041 (73.0%) made an insulin claim. We found a negligible difference in the temporal change in HbA1c during compared with before OHIP+ coverage that was not statistically significant (β estimate −0.0002, 95% confidence interval [CI] −0.0004 to 0.0000). The size of the effect was slightly greater in those individuals with the lowest SES than in those with the highest SES (β estimate −0.0008, 95% CI −0.0015 to −0.0001). Interpretation: We found that the effect of OHIP+ on the change in HbA1c was slightly greater for youth in the lowest SES than for those in the highest SES. Our findings suggest that publicly funded pharmacare may be an effective policy tool to combat worsening socioeconomic disparities in diabetes care and outcomes.
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