教育与环境痴呆的危险因素:文献综述

Juergen Gallistl
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引用次数: 0

摘要

引言和背景:痴呆症有许多不同的病因。痴呆症被认为是一种多因素疾病;因此,每个案例的因素之间的相互作用是一项复杂的研究。早期和最近的综述已经认识到与痴呆症和AD相关的几个风险因素。研究最多的风险因素包括遗传、年龄增长、教育、环境和脑损伤。这篇综述旨在通过选择最近的高质量资源并在本综述中对其进行总结,让读者了解有关痴呆症教育和环境风险因素的最新研究。方法:本文是一篇叙述性综述,对广泛的文献进行研究。结果和讨论:对证据的全面审查支持以下内容。首先,低教育程度可被视为患痴呆症的相关风险因素,尽管在许多研究中“低教育程度”的具体实施仍不清楚。“认知储备”的机制在教育和痴呆症之间的关系中具有重要意义,这一点在智力障碍患者中的研究是有局限性的。其次,空气污染现在被认为是痴呆症的风险因素,有大量关于PM2.5的证据,但由于“多次暴露反应”,关于单一气体污染物的证据较少。结论:大量研究表明,这些风险因素与痴呆症患病率之间存在关联。低收入和中等收入国家将受益于优先考虑全民儿童教育,因为教育是痴呆症和各种健康差异的主要风险因素之一。
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Education and Environment Dementia Risk Factors: A Literature Review
Introduction and Background: Dementia has many different causes. Dementia is considered a multifactorial disease; hence the interplay between factors for every case is a complex study. Early and recent reviews had recognised several risk factors associated with dementia in general and with AD specifically. The most studied risk factors include genetics, increasing age, education, environment, and brain injuries. This review aims to give readers access to the latest research on the educational and environmental risk factors of dementia by selecting recent high-quality resources and summarising them in this review. Methods: The current article is a narrative review of broad literature research. Results and Discussion: The comprehensive examination of evidence supports the following. First, low education can be considered a relevant risk factor for developing dementia, although the operationalisation of "low education" is still unclear in many studies. The mechanisms of "cognitive reserve" have an important implication in the relationships between education and dementia, and this has been studied with limitations in people with intellectual disorders. Second, air pollution is now considered a dementia risk factor with plenty of evidence concerning PM2.5 but less conclusive evidence regarding single gaseous pollutants because of the “multi-exposure response.” Conclusion: The considerable body of research points towards an association between these risk factors and dementia prevalence. Low- and middle-income countries will benefit from prioritising child education for all since education is one of the major risk factors for dementia and a wide variety of health disparities.
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来源期刊
Journal of Intellectual Disability - Diagnosis and Treatment
Journal of Intellectual Disability - Diagnosis and Treatment Social Sciences-Health (social science)
CiteScore
1.00
自引率
0.00%
发文量
29
期刊介绍: The journal aims to describe the research work on Intellectual Disability Diagnosis and Treatment in children and adults. It covers not just the technical aspects of the procedures in prenatal, newborn and postnatal screening, but also the impact which the process of testing and treatment has on individuals, parents, families and public-health in general. The journal seeks to publish, but is a not restricted to, Genetic Intellectual Disability Syndromes, using a range of approaches from medicine, psychiatry, psychology, pharmacy, biology, epidemiology, bioinformatics, biopharmaceutical to association and population studies as well as sociological, ethical, philosophical, legal and quality control issues with the ultimate goal of advancing the knowledge on the diagnosis, prevention, and treatment of the Intellectual Disabilities. The journal publishes original research articles, review articles, case reports and short communications(Letter article).
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