凝胶化乙醇经皮硬化治疗头颈部低流量血管畸形:初步结果。

IF 2.1 4区 医学 Q2 Medicine Diagnostic and Interventional Radiology Pub Date : 2019-10-25 DOI:10.5152/dir.2019.18542
A. Ierardi, G. Colletti, P. Biondetti, M. Dessy, G. Carrafiello
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引用次数: 8

摘要

目的评价凝胶化乙醇经皮硬化治疗低血流畸形的安全性和有效性。方法回顾性分析6例低流量畸形(LF-Ms)患者(3例淋巴和3例静脉)的治疗和预后资料。LF-Ms的中位直径为6 cm(直径4.5-8.5 cm)。评估有关疼痛、功能和/或外观问题的数据。临床诊断和多普勒超声确诊,同时通过磁共振成像(MRI)评估疾病的扩展。经皮穿刺采用23G针直接穿刺或超声引导。所有LF-Ms均用凝胶化乙醇注射液处理。每次治疗的中位注射量为4.4 ml。结果所有病例均获得了技术和临床成功。在中位随访17个月(12-19个月)期间无复发记录。6例患者中,83%的患者完全缓解(5/6),其余患者症状改善。治疗前VAS评分中位数为7分(iqr 6-7.5),治疗后为0分(iqr 0-0)。所有患者的功能和美观均有改善(100%)。极好接受4例(66.7%),良好接受2例(33.3%)。无主要并发症及全身副作用。结论经纯化的乙醇在短期随访中操作简便、耐受性好、安全有效。更长的随访疗效是进一步结论的必要条件。
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Percutaneous sclerotherapy with gelified ethanol of low-flow vascular malformations of the head and neck region: preliminary results.
PURPOSE Evaluation of safety and efficacy of percutaneous sclerotherapy using gelified ethanol in patients with low-flow malformations. METHODS A retrospective study was performed, analyzing treatment and outcome data of 6 patients that presented with 7 low-flow malformations (LF-Ms) (3 lymphatic and 3 venous). Median diameter of LF-Ms was 6 cm (iqr 4.5-8.5 cm). Data regarding pain, functional and/or cosmetic issues were assessed. Diagnosis was performed clinically and confirmed Doppler Ultrasound, while extension of disease was assessed by Magnetic Resonance Imaging (MRI). Percutaneous puncture was performed with 23G needle directly or with ultrasound guidance. All the LF-Ms were treated with gelified ethanol injection. The median volume injected per treatment session resulted 4.4 mL. RESULTS Technical and clinical success were obtained in all cases. No recurrences were registered during a median follow up of 17 months (iqr 12-19 months). Among the 6 patients, 83% of the patients had complete relief (5/6) and the other showed improvement of symptoms. The median VAS score was 7 (iqr 6-7.5) before and 0 (iqr 0-0) after treatment. All patients had functional and aesthetic improvement (100%). Four patients (66.7%) had a very good acceptance and two patients (33.3%) a good acceptance. No major complications neither systemic side effects were observed. CONCLUSION Gelified ethanol may be considered easy to handle, well-tolerated, safe and effective in the short-term follow up. Longer follow up efficacy is mandatory for further conclusions.
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来源期刊
CiteScore
3.50
自引率
4.80%
发文量
69
审稿时长
6-12 weeks
期刊介绍: Diagnostic and Interventional Radiology (Diagn Interv Radiol) is the open access, online-only official publication of Turkish Society of Radiology. It is published bimonthly and the journal’s publication language is English. The journal is a medium for original articles, reviews, pictorial essays, technical notes related to all fields of diagnostic and interventional radiology.
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