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Application of deep learning and radiomics in the prediction of hematoma expansion in intracerebral hemorrhage: a fully automated hybrid approach. 深度学习和放射组学在预测脑出血血肿扩大中的应用:一种全自动混合方法。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2024-04-24 DOI: 10.4274/dir.2024.222088
Mengtian Lu, Yaqi Wang, Jiaqiang Tian, Haifeng Feng
PURPOSESpontaneous intracerebral hemorrhage (ICH) is the most severe form of stroke. The timely assessment of early hematoma enlargement and its proper treatment are of great significance in curbing the deterioration and improving the prognosis of patients with ICH. This study aimed to develop an automated hybrid approach to predict hematoma expansion in ICH.METHODSThe transfer learning method was applied to build a hybrid model based on a convolutional neural network (CNN) to predict the expansion of hematoma. The model integrated (1) a CNN for automated hematoma segmentation and (2) a CNN-based classifier for hematoma expansion prediction that incorporated both 2-dimensional images and the radiomics features of the 3-dimensional hematoma shape.RESULTSThe radiomics feature module had the highest area under the receiver operating characteristic curve (AUC) of 0.58, a precision of 0, a recall of 0, and an average precision (AP) of 0.26. The ResNet50 and Inception_v3 modules had AUCs of 0.79 and 0.93, a precision of 0.56 and 0.86, a recall of 0.42 and 0.75, and an AP of 0.51 and 0.85, respectively. Radiomic with Inception_v3 and Radiomic with ResNet50 had AUCs of 0.95 and 0.81, a precision of 0.90 and 0.57, a recall of 0.79 and 0.17, and an AP of 0.87 and 0.69, respectively.CONCLUSIONA model using deep learning and radiomics was successfully developed. This model can reliably predict the hematoma expansion of ICH with a fully automated process based on non-contrast computed tomography imaging. Furthermore, the radiomics fusion with the Inception_v3 model had the highest accuracy.
目的自发性脑内出血(ICH)是中风中最严重的一种。及时评估早期血肿扩大并进行适当治疗,对遏制 ICH 患者病情恶化和改善预后具有重要意义。本研究旨在开发一种预测 ICH 中血肿扩大的自动化混合方法。该模型整合了:(1)用于自动血肿分割的 CNN;(2)基于 CNN 的血肿扩张预测分类器,该分类器同时整合了二维图像和三维血肿形状的放射组学特征。ResNet50 和 Inception_v3 模块的 AUC 分别为 0.79 和 0.93,精确度分别为 0.56 和 0.86,召回率分别为 0.42 和 0.75,平均精确度分别为 0.51 和 0.85。使用 Inception_v3 的 Radiomic 和使用 ResNet50 的 Radiomic 的 AUC 分别为 0.95 和 0.81,精确度分别为 0.90 和 0.57,召回率分别为 0.79 和 0.17,AP 分别为 0.87 和 0.69。该模型基于非对比度计算机断层扫描成像,以全自动流程可靠地预测了 ICH 的血肿扩大情况。此外,放射组学与 Inception_v3 模型的融合具有最高的准确性。
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引用次数: 0
Diagnostic value of qualitative and quantitative enhancement parameters on contrast-enhanced mammography. 对比增强乳腺 X 射线摄影中定性和定量增强参数的诊断价值。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2024-04-15 DOI: 10.4274/dir.2024.232472
Musa Kul, Selçuk Akkaya, Sibel Kul
PURPOSETo determine whether qualitative and quantitative enhancement parameters obtained from contrast-enhanced mammography (CEM) can be used in predicting malignancy.METHODSAfter review board approval, consecutive 136 suspicious lesions with definite diagnosis were retrospectively analyzed on CEM. Acquisition was routinely started with craniocaudal view and ended with mediolateral oblique view of the affected breast. Lesion conspicuity (low, moderate, high), internal enhancement pattern (homogeneous, heterogeneous, rim), contrast-to-noise ratio (CNR), percentage of signal difference (PSD) and relative enhancement from early to late view were analyzed. PSD and relative enhancements were used to determine patterns of descending, steady or ascending enhancements. Receiver operating characteristic analysis, Cohen's kappa statistics and Spearman correlation tests were used.RESULTSThere were 29 benign and 107 malignant lesions. 64% of the malignant lesions exhibited high conspicuity compared to 14% of the benign lesions (P < 0.001). CNR values were higher in malignant lesions compared to benign ones (P ≤ 0.004). CNR from early view yielded 82% sensitivity, 72% specificity and PSD yielded 79% sensitivity, 65% specificity. Descending pattern and rim enhancement observed in 44% and 21% of breast cancers, respectively, and both provided 96% positive predictive value for malignancy.CONCLUSIONDiagnostic accuracy of quantitative parameters was higher than that of qualitative parameters. High CNR, rim enhancement, and descending pattern were features commonly seen in malignant lesions, while low CNR, homogeneous enhancement, and ascending pattern were commonly seen in benign lesions.
目的确定造影剂增强乳腺 X 线摄影(CEM)获得的定性和定量增强参数是否可用于预测恶性肿瘤。方法经审查委员会批准后,对连续 136 例有明确诊断的可疑病变进行 CEM 回顾性分析。采集时常规从患侧乳房的头颅后方切面开始,以内侧斜切面结束。分析了病变的清晰度(低、中、高)、内部增强模式(均质、异质、边缘)、对比度与噪声比(CNR)、信号差百分比(PSD)以及从早期视图到晚期视图的相对增强情况。PSD 和相对增强用于确定下降型、稳定型或上升型增强模式。结果29个良性病变和107个恶性病变。64%的恶性病变表现出高度的明显性,而良性病变仅为 14%(P < 0.001)。恶性病变的 CNR 值高于良性病变(P ≤ 0.004)。早期视图的 CNR 敏感性为 82%,特异性为 72%,而 PSD 的敏感性为 79%,特异性为 65%。在44%和21%的乳腺癌中分别观察到了下降模式和边缘增强,两者对恶性肿瘤的阳性预测值均为96%。高CNR、边缘强化和下降模式是恶性病变的常见特征,而低CNR、均匀强化和上升模式则常见于良性病变。
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引用次数: 0
Post-contrast abdominal magnetic resonance imaging of critically ill patients using compressed sensing free-breathing golden radial angle imaging. 使用压缩传感自由呼吸黄金径向角成像对重症患者进行对比后腹部磁共振成像。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2024-04-05 DOI: 10.4274/dir.2024.232646
Anup S. Shetty, M. Hoegger, Koushik K Das
Obtaining diagnostic-quality magnetic resonance imaging (MRI) of the abdomen in critically ill patients can be difficult due to challenges with breath-holding and the inability to follow technologist instructions. Protocols that harness advances in commercially available MRI techniques provide a potential solution, particularly using the golden radial angle sparse parallel (GRASP) technique for dynamic post-contrast T1-weighted imaging. The GRASP technique uses a combination of free-breathing, a stack-of-stars radial acquisition, and compressed sensing reconstruction acquired over several minutes to produce motion-free images at time points defined by the user; these include the non-contrast, arterial, venous, and delayed images, which are typical of abdominal MRI protocols. The three cases discussed herein illustrate the use of this technique in providing both exquisite image quality and diagnostic value in the care of critically ill patients with hepatopancreaticobiliary diseases. Our work aims to raise awareness of this technique and its utility in imaging patients who cannot hold their breath for dynamic T1-weighted post-contrast imaging.
由于憋气和无法听从技术人员的指导,危重病人难以获得诊断质量的腹部磁共振成像(MRI)。利用市场上先进的磁共振成像技术提供了一种潜在的解决方案,尤其是使用黄金径向角稀疏平行(GRASP)技术进行动态对比后 T1 加权成像。GRASP 技术结合使用自由呼吸、星状堆叠径向采集和压缩传感重建,在用户定义的时间点生成无运动图像;这些图像包括非对比、动脉、静脉和延迟图像,是腹部 MRI 方案的典型特征。本文讨论的三个病例说明了该技术在肝胆胰疾病重症患者护理中的应用,既能提供精美的图像质量,又能提供诊断价值。我们的工作旨在提高人们对这项技术及其在无法屏住呼吸进行动态 T1 加权对比后成像的患者成像中的实用性的认识。
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引用次数: 0
Arterial input function for quantitative dynamic contrast-enhanced MRI to diagnose prostate cancer. 定量动态增强MRI诊断前列腺癌的动脉输入功能。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2022-03-01 DOI: 10.5152/dir.2022.19512
F. Ziayee, Anja Mueller-Lutz, Janina Groß, T. Ullrich, M. Quentin, C. Arsov, G. Antoch, H. Wittsack, L. Schimmöller
PURPOSE This study aims to analyze the ability of quantitative dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to distinguish between prostate cancer (PCa) and benign lesions in transition zone (TZ) and peripheral zone (PZ) using different methods for arterial input function (AIF) determination. Study endpoints are identification of a standard AIF method and optimal quantitative perfusion parameters for PCa detection. METHODS DCE image data of 50 consecutive patients with PCa who underwent multiparametric MRI were analyzed retrospectively with three different methods of AIF acquisition. First, a region of interest was manually defined in an artery (AIFm); second, an automated algorithm was used (AIFa); and third, a population-based AIF (AIFp) was applied. Values of quantitative parameters after Tofts (Ktrans, ve, and kep) in PCa, PZ, and TZ in the three different AIFs were analyzed. RESULTS Ktrans and kep were significantly higher in PCa than in benign tissue independent from the AIF method. Whereas in PZ, Ktrans and kep could differentiate PCa (P < .001), in TZ only kep using AIFpdemonstrated a significant difference (P = .039). The correlations of the perfusion parameters that resulted from AIFm and AIFa were higher than those that resulted from AIFp, and the absolute values of Ktrans, kep, and ve were significantly lower when using AIFp. The values of quantitative perfusion parameters for PCa were similar regardless of whether PCa was located in PZ or TZ. CONCLUSION Ktrans and kep were able to differentiate PCa from benign PZ independent of the AIF method. AIFaseems to be the most feasible method of AIF determination in clinical routine. For TZ, none of the quantitative perfusion parameters provided satisfying results.
目的本研究旨在分析定量动态对比增强磁共振成像(DCE-MRI)采用不同的动脉输入功能(AIF)测定方法对前列腺癌(PCa)与过渡区(TZ)和外周区(PZ)良性病变的鉴别能力。研究的终点是确定一种标准的AIF方法和用于PCa检测的最佳定量灌注参数。方法回顾性分析50例连续行多参数MRI检查的PCa患者的DCE图像资料,采用三种不同的AIF获取方法。首先,在动脉中手动定义感兴趣的区域(AIFm);其次,采用自动算法(AIFa);第三,应用基于人群的AIFp (AIFp)。分析三种不同AIFs中PCa、PZ、TZ的Tofts后定量参数(Ktrans、ve、keep)值。结果前列腺癌组织中Ktrans和kep的表达明显高于非AIF法的良性组织。而在PZ中,Ktrans和kep可以区分PCa (P < 0.001),而在TZ中,只有ketrans和kep可以区分PCa (P = 0.039)。AIFm与AIFa的灌注参数相关性均高于AIFp,且使用AIFp时Ktrans、keep、ve的绝对值均显著降低。无论PCa位于PZ还是TZ,其定量灌注参数值都是相似的。结论Ktrans和kep能独立于AIF法鉴别前列腺癌与良性PZ。在临床常规中,AIF的测定是最可行的方法。对于TZ,没有一个定量灌注参数提供令人满意的结果。
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引用次数: 2
Percutaneous sclerotherapy using a 4 F pigtail catheter and 40 milliliters of 5% ethanolamine oleate for symptomatic large hepatic cysts. 经皮硬化治疗使用4f细尾导管和40毫升5%油酸乙醇胺治疗有症状的大肝囊肿。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2022-03-01 DOI: 10.5152/dir.2022.20765
S. Miyayama, M. Yamashiro, R. Ikeda, Junichi Matsumoto, Nobuhiko Ogawa, K. Notsumata
PURPOSE We retrospectively evaluated the efficacy of percutaneous sclerotherapy using a 4 F catheter and 40 mL of 5% ethanolamine oleate (EO) for symptomatic large hepatic cysts. METHODS Twenty-four patients, including 10 with polycystic liver disease (PLD), were eligible. The mean long- and short-axis diameters of the cyst on computed tomography (CT) were 145.0 ± 35.5 mm (range, 72-216 mm) and 110.5 ± 21.4 mm (range, 63-150 mm), respectively. After aspiration of the fluid contents using a 4 F pigtail catheter, 40 mL of 5% EO was injected into the cyst for 30 min. Then, the catheter was withdrawn after EO removal. Symptomatic relief and complications were evaluated. The percentage reductions at the early (1-3 months later) and late (at the final follow-up) responses were evaluated using an estimated cyst volume calculated by using the following formula: volume = π/6 × long-axis diameter × (short-axis diameter)2 on the maximum cross-section image on CT. Spearman's rank correlation coefficient (ρ) was used to evaluate the correlation between the pretreatment estimated cyst volume and percentage reduction of early and late responses and between the percentage reduction of the late response and length of the follow-up period after sclerotherapy. RESULTS The symptoms disappeared in 23 patients and improved in 1 patient with PLD. The mean aspirated fluid volume was 1337.8 ± 845.4 mL (range, 140-3200 mL). In 1 patient, EO injection was postponed until the second procedure was performed 40 days later due to intraperitoneal leakage of contrast material. In another patient, the EO volume was reduced to 20 mL because of a small cyst size. The mean early and late percentage reductions of the treated cyst were 52.3% ± 23.8% and 87.5% ± 20.4% (mean follow-up period: 48.0 ± 42.4 months), respectively. The symptom recurred in 2 patients with PLD and 1 underwent additional sclerotherapy 14 months later due to re-enlargement of the treated cyst. Another patient underwent transarterial embolization 5 years and 4 months later for other enlarged cysts, although the treated cyst markedly shrank. There were significant negative correlations between the pretreatment estimated cyst volume and percentage reduction of early (P = .027, ρ = - 0.46) and late (P= .007, ρ = - 0.52) responses. However, there were no significant correlations between the percentage reduction and length of the follow-up period (P = .19, ρ = 0.31). Transient pain developed in 1 patient and low-grade fever in 3. CONCLUSION Sclerotherapy using a 4 F catheter and 40 mL of 5% EO is safe and effective for symptomatic large hepatic cysts.
我们回顾性评估了使用4F导管和40mL 5%油酸乙醇胺(EO)经皮硬化治疗症状性大肝囊肿的疗效。方法24例患者,其中10例为多囊肝患者。计算机断层扫描(CT)上囊肿的平均长轴和短轴直径分别为145.0±35.5 mm(范围72-216 mm)和110.5±21.4 mm(范围63-150 mm)。在使用4F猪尾导管抽吸液体内容物后,将40mL的5%EO注射到囊肿中30分钟。然后,在EO移除后拔出导管。评估症状缓解和并发症。早期(1-3个月后)和晚期(最终随访时)反应的减少百分比使用估计的囊肿体积进行评估,该体积通过使用以下公式计算:CT最大横截面图像上的体积=π/6×长轴直径×(短轴直径)2。Spearman秩相关系数(ρ)用于评估预处理估计的囊肿体积与早期和晚期反应减少百分比之间的相关性,以及硬化治疗后后期反应减少百分比与随访时间长度之间的相关性。结果PLD患者症状消失23例,好转1例。平均吸入液体体积为1337.8±845.4 mL(范围为140-3200 mL)。在1名患者中,由于造影剂腹膜内渗漏,EO注射被推迟到40天后进行第二次手术。在另一名患者中,由于囊肿大小较小,EO体积减少至20mL。治疗囊肿的早期和晚期平均减少百分比分别为52.3%±23.8%和87.5%±20.4%(平均随访期:48.0±42.4个月)。2例PLD患者症状复发,1例在14个月后因治疗后的囊肿再次扩大而接受了额外的硬化治疗。另一名患者在5年零4个月后因其他增大的囊肿接受了动脉栓塞治疗,尽管治疗后的囊肿明显缩小。预处理估计的囊肿体积与早期(P=0.027,ρ=-0.46)和晚期(P=0.007,ρ=-0.52)反应的减少百分比之间存在显著的负相关。然而,减少百分比与随访时间之间没有显著相关性(P=.19,ρ=0.31)。1名患者出现短暂疼痛,3名患者出现低热。结论使用4F导管和40mL 5%EO进行硬化治疗症状性大肝囊肿是安全有效的。
{"title":"Percutaneous sclerotherapy using a 4 F pigtail catheter and 40 milliliters of 5% ethanolamine oleate for symptomatic large hepatic cysts.","authors":"S. Miyayama, M. Yamashiro, R. Ikeda, Junichi Matsumoto, Nobuhiko Ogawa, K. Notsumata","doi":"10.5152/dir.2022.20765","DOIUrl":"https://doi.org/10.5152/dir.2022.20765","url":null,"abstract":"PURPOSE We retrospectively evaluated the efficacy of percutaneous sclerotherapy using a 4 F catheter and 40 mL of 5% ethanolamine oleate (EO) for symptomatic large hepatic cysts. METHODS Twenty-four patients, including 10 with polycystic liver disease (PLD), were eligible. The mean long- and short-axis diameters of the cyst on computed tomography (CT) were 145.0 ± 35.5 mm (range, 72-216 mm) and 110.5 ± 21.4 mm (range, 63-150 mm), respectively. After aspiration of the fluid contents using a 4 F pigtail catheter, 40 mL of 5% EO was injected into the cyst for 30 min. Then, the catheter was withdrawn after EO removal. Symptomatic relief and complications were evaluated. The percentage reductions at the early (1-3 months later) and late (at the final follow-up) responses were evaluated using an estimated cyst volume calculated by using the following formula: volume = π/6 × long-axis diameter × (short-axis diameter)2 on the maximum cross-section image on CT. Spearman's rank correlation coefficient (ρ) was used to evaluate the correlation between the pretreatment estimated cyst volume and percentage reduction of early and late responses and between the percentage reduction of the late response and length of the follow-up period after sclerotherapy. RESULTS The symptoms disappeared in 23 patients and improved in 1 patient with PLD. The mean aspirated fluid volume was 1337.8 ± 845.4 mL (range, 140-3200 mL). In 1 patient, EO injection was postponed until the second procedure was performed 40 days later due to intraperitoneal leakage of contrast material. In another patient, the EO volume was reduced to 20 mL because of a small cyst size. The mean early and late percentage reductions of the treated cyst were 52.3% ± 23.8% and 87.5% ± 20.4% (mean follow-up period: 48.0 ± 42.4 months), respectively. The symptom recurred in 2 patients with PLD and 1 underwent additional sclerotherapy 14 months later due to re-enlargement of the treated cyst. Another patient underwent transarterial embolization 5 years and 4 months later for other enlarged cysts, although the treated cyst markedly shrank. There were significant negative correlations between the pretreatment estimated cyst volume and percentage reduction of early (P = .027, ρ = - 0.46) and late (P= .007, ρ = - 0.52) responses. However, there were no significant correlations between the percentage reduction and length of the follow-up period (P = .19, ρ = 0.31). Transient pain developed in 1 patient and low-grade fever in 3. CONCLUSION Sclerotherapy using a 4 F catheter and 40 mL of 5% EO is safe and effective for symptomatic large hepatic cysts.","PeriodicalId":50582,"journal":{"name":"Diagnostic and Interventional Radiology","volume":"28 2 1","pages":"149-155"},"PeriodicalIF":2.1,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42815146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of COVID-19 pandemic on radiology literature. 新冠肺炎大流行对放射学文献的影响。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2022-03-01 DOI: 10.5152/dir.2022.21438
H. Şendur, M. Cerit, Aylin Billur Şendur
{"title":"Impact of COVID-19 pandemic on radiology literature.","authors":"H. Şendur, M. Cerit, Aylin Billur Şendur","doi":"10.5152/dir.2022.21438","DOIUrl":"https://doi.org/10.5152/dir.2022.21438","url":null,"abstract":"","PeriodicalId":50582,"journal":{"name":"Diagnostic and Interventional Radiology","volume":"28 2 1","pages":"185"},"PeriodicalIF":2.1,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49424316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relative contribution of susceptibility weighted imaging, compared to conventional MRI, in the detection of common bile-duct calculi. 与传统MRI相比,磁化率加权成像在检测胆总管结石中的相对贡献。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2022-03-01 DOI: 10.5152/dir.2022.20713
Vishal Singh, J. Neelavalli, Suhail P. Parvaze, Mamta Gupta, R. K. Verma, A. Seth, Lakshay Mehta, Rakesh K. Gupta
PURPOSE We aimed to evaluate the relative contribution of susceptibility weighted imaging (SWI) in the detection of common bile-duct (CBD) stones in comparison to the conventional MRI protocol containing magnetic resonance cholangiopancreatography (MRCP), balanced turbo field echo (BTFE), and T2-weighted spin-echo imaging techniques. METHODS MRI data containing MRCP, BTFE, T2-weighted imaging, and abdominal SWI were independently evaluated by 2 sets of experienced radiologists in 44 patients with confirmed CBD stones. Endoscopic retrograde cholangiopancreatography, and endoscopic ultrasound where available, was used as the reference gold standard. Evaluation was performed for the visualization of CBD stones in each of the MRI techniques. Relative contribution of SWI was classified into one of four categories for each case: (1) no contribution to CBD stone visualization; (2) same as conventional techniques; (3) improved diagnostic confidence; and (4) critical for diagnosis. Stone size was also assessed. RESULTS Inter-rater agreement coefficient for CBD stone visualization was found to be "good" in MRCP (0.77), "very good" in SWI (0.94) and BTFE (0.84), and moderate in T2-weighted imaging (0.54). CBD stones were visualized with SWI in 86.4% and 82%, with MRCP in 70.5% and 70.5% cases, with BTFE in 73% and 61.4% cases, with T2-weighted imaging in 45.5% and 52.3% cases by reviewers 1 and 2, respectively. SWI did not contribute to CBD stone visualization in 2.3% (1/44); was the same as conventional techniques in 31.8% (14/44) cases; improved diagnostic confidence in 34.1%; and was critical for diagnosis in 20.5% cases. CONCLUSION SWI has the potential to serve as a strong adjunct to conventional MRI protocols used for CBD stone evaluation with very small scan-time penalty.
我们旨在评估磁化率加权成像(SWI)在检测胆总管(CBD)结石方面的相对贡献,与包含磁共振胰胆管成像(MRCP)、平衡涡轮场回波(BTFE)和T2加权自旋回波成像技术的传统MRI方案相比。方法由2组经验丰富的放射科医生对44例确诊为CBD结石的患者的MRI数据进行独立评估,包括MRCP、BTFE、T2加权成像和腹部SWI。内窥镜逆行胰胆管造影和内窥镜超声(如有)被用作参考金标准。对每种MRI技术中CBD结石的可视化进行评估。SWI的相对贡献被分为四类之一:(1)对CBD结石可视化没有贡献;(2) 与传统技术相同;(3) 提高诊断置信度;和(4)对诊断至关重要。还评估了石头的大小。结果MRCP显示CBD结石的评分者间一致性系数为“良好”(0.77),SWI(0.94)和BTFE(0.84)为“非常好”,T2加权成像为中等(0.54),分别地在2.3%(1/44)中,SWI对CBD结石可视化没有贡献;31.8%(14/44)的病例与传统技术相同;诊断置信度提高34.1%;20.5%的病例对诊断具有重要意义。结论SWI有潜力作为传统MRI方案的有力辅助,用于CBD结石评估,扫描时间损失很小。
{"title":"Relative contribution of susceptibility weighted imaging, compared to conventional MRI, in the detection of common bile-duct calculi.","authors":"Vishal Singh, J. Neelavalli, Suhail P. Parvaze, Mamta Gupta, R. K. Verma, A. Seth, Lakshay Mehta, Rakesh K. Gupta","doi":"10.5152/dir.2022.20713","DOIUrl":"https://doi.org/10.5152/dir.2022.20713","url":null,"abstract":"PURPOSE We aimed to evaluate the relative contribution of susceptibility weighted imaging (SWI) in the detection of common bile-duct (CBD) stones in comparison to the conventional MRI protocol containing magnetic resonance cholangiopancreatography (MRCP), balanced turbo field echo (BTFE), and T2-weighted spin-echo imaging techniques. METHODS MRI data containing MRCP, BTFE, T2-weighted imaging, and abdominal SWI were independently evaluated by 2 sets of experienced radiologists in 44 patients with confirmed CBD stones. Endoscopic retrograde cholangiopancreatography, and endoscopic ultrasound where available, was used as the reference gold standard. Evaluation was performed for the visualization of CBD stones in each of the MRI techniques. Relative contribution of SWI was classified into one of four categories for each case: (1) no contribution to CBD stone visualization; (2) same as conventional techniques; (3) improved diagnostic confidence; and (4) critical for diagnosis. Stone size was also assessed. RESULTS Inter-rater agreement coefficient for CBD stone visualization was found to be \"good\" in MRCP (0.77), \"very good\" in SWI (0.94) and BTFE (0.84), and moderate in T2-weighted imaging (0.54). CBD stones were visualized with SWI in 86.4% and 82%, with MRCP in 70.5% and 70.5% cases, with BTFE in 73% and 61.4% cases, with T2-weighted imaging in 45.5% and 52.3% cases by reviewers 1 and 2, respectively. SWI did not contribute to CBD stone visualization in 2.3% (1/44); was the same as conventional techniques in 31.8% (14/44) cases; improved diagnostic confidence in 34.1%; and was critical for diagnosis in 20.5% cases. CONCLUSION SWI has the potential to serve as a strong adjunct to conventional MRI protocols used for CBD stone evaluation with very small scan-time penalty.","PeriodicalId":50582,"journal":{"name":"Diagnostic and Interventional Radiology","volume":"28 2 1","pages":"131-137"},"PeriodicalIF":2.1,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48579107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of MWA protocols upon morphology and IVIM parameters of hepatic ablation zones-a preliminary in vivo animal study with an MRI-compatible microwave ablation device. MWA方案对肝脏消融区形态和IVIM参数的影响- mri兼容微波消融装置的初步体内动物研究。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2022-03-01 DOI: 10.5152/dir.2022.20292
Weitao Ye, Wanqun Yang, Cheng-wei Guo, Chenyu Dong, F. Shi, C. Liang
PURPOSE We aimed to explore the effect of microwave ablation (MWA) protocols upon morphology and instant changes in intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI) parameters on MWA zones in porcine livers. METHODS According to the empirical protocol for MWA in tumors less than 3 cm in our hospital, the power and application duration were assigned as five groups: A, 60 W × 5 min (n = 6); B, 80 W × 3 min (n = 7); C, 80 W × 5 min (n = 10); D, 100 W × 3 min (n = 10); E, 100 W × 5 min (n = 9). Spearman correlation between MWA protocols, morphological metrics, and instant post-ablation IVIM parameters was performed. RESULTS There was fair positive correlation between energy delivery and short axis (RSpearman = 0.426, P= .005) of the white zone. There was moderate-to-good positive correlation between wattage and short axis (RSpearman = 0.584, P < .001) of the white zone. For post-ablation IVIM parameters in the white zone, only wattage had moderate-to-good positive correlation with D value (RSpearman= 0.574, P < .001) or ADC value (RSpearman = 0.550, P < .001). No correlation between energy delivery, wattage, duration, and f value was observed (RSpearman = 0.185, P = .24; RSpearman= - 0.001, P = .99; RSpearman = 0.203, P = .20, respectively). CONCLUSION The increase in the short axis of the white zone is more likely to be affected by wattage than energy delivery. The instant post-ablation IVIM is feasible in monitoring the MWA zones since the f value in the white zones is not sensitive to changes in MWA protocols, which is promising in evaluating the instant effect of MWA.
目的探讨微波消融(MWA)方案对猪肝MWA区形态及体素内非相干运动(IVIM)扩散加权成像(DWI)参数瞬时变化的影响。方法根据我院小于3cm肿瘤MWA的经验方案,将功率和使用时间分为5组:A、60 W × 5 min (n = 6);B, 80 W × 3 min (n = 7);C, 80 W × 5 min (n = 10);D, 100 W × 3 min (n = 10);E, 100 W × 5 min (n = 9)。对MWA方案、形态学指标和消融后即时IVIM参数进行Spearman相关性分析。结果能量传递与白区短轴呈显著正相关(RSpearman = 0.426, P= 0.005)。白带的瓦数与短轴呈中等至良好的正相关(RSpearman = 0.584, P < 0.001)。消融后白区IVIM参数中,只有瓦数与D值(RSpearman= 0.574, P < .001)或ADC值(RSpearman= 0.550, P < .001)呈正相关。能量输送、瓦数、持续时间和f值之间无相关性(RSpearman = 0.185, P = 0.24;RSpearman= - 0.001, P = 0.99;RSpearman = 0.203, P = 0.20)。结论白区短轴的增加更容易受到功率的影响,而不是能量输送的影响。消融后瞬间IVIM监测MWA区域是可行的,因为白色区域的f值对MWA协议的变化不敏感,这在评价MWA的即时效果方面是有希望的。
{"title":"The effect of MWA protocols upon morphology and IVIM parameters of hepatic ablation zones-a preliminary in vivo animal study with an MRI-compatible microwave ablation device.","authors":"Weitao Ye, Wanqun Yang, Cheng-wei Guo, Chenyu Dong, F. Shi, C. Liang","doi":"10.5152/dir.2022.20292","DOIUrl":"https://doi.org/10.5152/dir.2022.20292","url":null,"abstract":"PURPOSE We aimed to explore the effect of microwave ablation (MWA) protocols upon morphology and instant changes in intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI) parameters on MWA zones in porcine livers. METHODS According to the empirical protocol for MWA in tumors less than 3 cm in our hospital, the power and application duration were assigned as five groups: A, 60 W × 5 min (n = 6); B, 80 W × 3 min (n = 7); C, 80 W × 5 min (n = 10); D, 100 W × 3 min (n = 10); E, 100 W × 5 min (n = 9). Spearman correlation between MWA protocols, morphological metrics, and instant post-ablation IVIM parameters was performed. RESULTS There was fair positive correlation between energy delivery and short axis (RSpearman = 0.426, P= .005) of the white zone. There was moderate-to-good positive correlation between wattage and short axis (RSpearman = 0.584, P < .001) of the white zone. For post-ablation IVIM parameters in the white zone, only wattage had moderate-to-good positive correlation with D value (RSpearman= 0.574, P < .001) or ADC value (RSpearman = 0.550, P < .001). No correlation between energy delivery, wattage, duration, and f value was observed (RSpearman = 0.185, P = .24; RSpearman= - 0.001, P = .99; RSpearman = 0.203, P = .20, respectively). CONCLUSION The increase in the short axis of the white zone is more likely to be affected by wattage than energy delivery. The instant post-ablation IVIM is feasible in monitoring the MWA zones since the f value in the white zones is not sensitive to changes in MWA protocols, which is promising in evaluating the instant effect of MWA.","PeriodicalId":50582,"journal":{"name":"Diagnostic and Interventional Radiology","volume":"28 2 1","pages":"115-123"},"PeriodicalIF":2.1,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41506813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CT-based differentiation of solid pseudopapillary neoplasm and nonfunctional neuroendocrine tumor of pancreas. 胰腺实性假乳头状瘤与无功能神经内分泌瘤的ct鉴别。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2022-03-01 DOI: 10.5152/dir.2022.20926
Yanqing Ma, Yang Wen, Jianguo Zhong
PURPOSE The purpose of this paper was to distinguish solid pseudopapillary neoplasms (SPNs) and nonfunctional neuroendocrine tumors (nf-NETs) of pancreas using univariate analysis and clinical-CT logistic regression model. METHODS Twenty-eight patients with SPNs and 46 patients with nf-NETs underwent enhanced CT examinations. Clinical data (sex, age), categorical (location, cystic degeneration, calcification, hemorrhage, and enhancement pattern), and numeric CT features (lesion long diameter, long/ short diameter ratio, tumor attenuation values and tumor/pancreas attenuation ratios at unenhanced phase [UP], arterial phase [AP], and venous phase [VP]) were recorded. The logistic regression model was constructed by stepwise forward method of binary logistic regression after univariate analysis. The corresponding operating characteristic curve (ROC) and nomogram were delineated. The area under the curve (AUC), sensitivity, and specificity of ROC were calculated. RESULTS The SPNs were observed more often in relatively young (P < .001), female (P < .001) patients. After the univariate analysis, the categorical CT features of location (P = .048), hemorrhage (P = .003), and enhancement pattern (P = .004) and the numeric CT features of lesion long diameter (P = .005), tumor/pancreasUP (P = .002), tumorAP (P < .001), and tumor/pancreasAP (P < .001) had statistical significance. The AUC (95% CI), sensitivity, and specificity of a logistic regression model composed of age, tumor/pancreasUP, and tumor/pancreasAP were 0.933 (95% CI, 0.850-0.978), 84.78%, and 92.86%. CONCLUSION The SPNs often occurred in 20- to 40-year-old female patients, were located in the body or tail of pancreas, showed hemorrhagic degeneration, heterogeneous enhancement, and were relatively larger in size compared with nf-NETs. Tumor/pancreasUP, tumorAP, and tumor/pancreasAP values of SPNs were smaller than those of nf-NETs. The clinical-CT logistic regression model and nomogram consisting of age, tumor/pancreasUP, and tumor/pancreasAP parameters helped to differentiate SPNs from nf-NETs.
目的应用单因素分析和临床CT逻辑回归模型,区分胰腺实体性假乳头状肿瘤(SPN)和非功能性神经内分泌肿瘤(nf NETs)。方法对28例SPN患者和46例nf-NETs患者进行增强CT检查。记录临床数据(性别、年龄)、分类(位置、囊性变性、钙化、出血和增强模式)和数字CT特征(病变长径、长短径比、肿瘤衰减值以及未增强期[UP]、动脉期[AP]和静脉期/VP]的肿瘤/胰腺衰减比)。通过单因素分析,采用二元logistic回归的逐步正演方法建立logistic回归模型。绘制了相应的工作特性曲线(ROC)和列线图。计算ROC的曲线下面积(AUC)、敏感性和特异性。结果SPN在相对年轻(P<0.001)和女性(P<.001)患者中更常见。单变量分析后,位置(P=.048)、出血(P=.003)和增强模式(P=.004)的分类CT特征,以及病变长径(P=.005)、肿瘤/胰腺UP(P=.002)、肿瘤AP(P<.001)和肿瘤/胰腺AP(P<.001)的数字CT特征具有统计学意义。由年龄、肿瘤/胰腺UP和肿瘤/胰腺AP组成的逻辑回归模型的AUC(95%CI)、敏感性和特异性分别为0.933(95%CI,0.850-0.978)、84.78%和92.86%,并且与nf NETs相比在尺寸上相对较大。SPN的肿瘤/胰腺UP、肿瘤AP和肿瘤/胰腺AP值小于nf NETs。由年龄、肿瘤/胰腺UP和肿瘤/胰腺AP参数组成的临床CT逻辑回归模型和列线图有助于区分SPN和nf NETs。
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引用次数: 1
Feasibility and accuracy of digital breast tomosynthesis-guided vacuum-assisted breast biopsy for noncalcified mammographic targets. 数字乳腺断层合成引导真空辅助乳腺活检用于非钙化乳腺靶点的可行性和准确性。
IF 2.1 4区 医学 Q2 Medicine Pub Date : 2022-03-01 DOI: 10.5152/dir.2022.20830
G. Senapati, S. Chikarmane, C. Denison, C. Giess
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引用次数: 2
期刊
Diagnostic and Interventional Radiology
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