MiRNA-337参与多种癌症

M. Alivand, Mahsa Fakeri, Seyed Masoud Armandzadeh, Shabnam Koulaeizadeh, Elmira Aboutalebi Vand Beilankouhi, Mohammad Valilo
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引用次数: 0

摘要

在哺乳动物等多细胞生物中,microRNAs (miRNA)在转录后水平调控基因表达方面发挥着重要作用。这些小的非编码rna (snRNA)可以存在于植物甚至病毒中,约占人类基因的60%。mirna发挥着许多不同的功能和作用,包括它们在许多疾病和癌症中的作用。近年来关于miRNA-337在癌症中的作用的各种研究结果表明,miR-337作为一种癌症抑制剂,通过抑制细胞侵袭在各种癌症的治疗中发挥关键作用。因此,在各种mirna中,我们旨在阐明miR-337在不同类型癌症中的功能。
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Involvement of MiRNA-337 in Various Cancers
microRNAs (miRNA) play a significant role in regulating gene expression at the post-transcriptional level in multicellular organisms, such as mammals. These small non-coding RNAs (snRNA) can be present in plants and even viruses, and make up about 60% of human genes. Many different functions and roles are played by miRNAs, including their role in many diseases and cancers. The results of various studies in recent years on the role of miRNA-337 in cancers have shown that miR-337 acts as a cancer inhibitor and can play a key role in the treatment of various cancers by inhibiting cell invasion. Thus, among the various miRNAs, in this review, we aim to shed light on the function of miR-337 in different types of cancer.
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来源期刊
CiteScore
1.00
自引率
0.00%
发文量
50
期刊介绍: Current Cancer Therapy Reviews publishes frontier reviews on all the latest advances in clinical oncology, cancer therapy and pharmacology. The journal"s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians in cancer therapy.
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