Hcv在印度北部的基因型分布

P. Malhotra
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摘要

引言:病毒性肝炎是印度和全球公认的公共卫生问题。各种病原体(甲型肝炎、乙型肝炎、丙型肝炎、丁型肝炎、戊型肝炎和庚型肝炎病毒)可能导致急性、慢性或急性对慢性感染。虽然甲型和戊型肝炎通常是散发性肝炎爆发的原因,但乙型和丙型肝炎可以自行清除,也可以导致慢性感染,随后如肝硬化和肝细胞癌(HCC)。目的:确定在PGIMS Rohtak消化内科就诊的慢性肝炎患者中HCV感染的基因分型。总结和结论我们的研究证实了先前研究的发现,即在印度,基因型3是最常见的基因型,很难用口服抗病毒治疗基因型。因此,根据世界卫生组织的目标,到2030年消除丙型肝炎需要在中心、国家和社会层面持续、持续和坚定的努力。
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Genotypic Distribution of Hcv in Northeren India
Introduction: Viral hepatitis is recognized as a public health problem in India and globally. Various etiological agents (Hepatitis A, B, C, D, E and G virus) have been implicated that can lead to acute, chronic or acute on chronic infection. While Hepatitis A and E are often the cause of sporadic outbreaks of hepatitis, Hepatitis B and C can either clear spontaneously or can lead to chronic infection and thereafter sequel like cirrhosis and hepatocellular carcinoma (HCC). Aims & objectives: To determine the genotyping of HCV infections among chronic hepatitis patients attending Department of Gastroenterology, PGIMS Rohtak. Summary and conclusions Our study confirms the finding of previous studies that in India Genotype 3 is most common genotype which is difficult to treat Genotype with oral antiviral therapy. Hence as per World Health Organization target of elimination of Hepatitis C till 2030 requires continuous, persistent and determined efforts at level of Center, State and society level.
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