Chengxiang Kong, P. Jin, Chun-yi Liu, Jin-ji Xu, Yong Luo, H. Xie, Gang Zhou
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引用次数: 0
摘要
Objective To investigate the effectiveness of extracorporeal membrane oxygenation (ECMO) in supporting the treatment of severe pertussis in infants. Method: A retrospective report was conducted on a 2-month-old child diagnosed with severe pertussis who received ECMO treatment at the PICU of Bao'an District Maternal and Child Health Hospital in Shenzhen in 2018. Literature review was conducted on the current status of severe pertussis and ECMO treatment, and the experience of ECMO support treatment for severe pertussis was summarized based on the case. As a result, 2-month-old male infants who were not vaccinated against pertussis developed symptoms after exposure to infected cases, including hyperleukopenia, severe pneumonia, pertussis encephalopathy, acute respiratory distress syndrome, heart failure, and shock. The routine treatment measures were ineffective, and there were stubborn hypoxemia, severe carbon dioxide retention, circulatory failure and other manifestations. VA-ECMO support treatment, combined with "lung rest" strategy, prone ventilation, restrictive fluid management, lung recruitment and other comprehensive treatment programs, was ultimately successful. Conclusion: Dynamic monitoring of white blood cells is helpful in determining the condition and prognosis. The inversion of the ratio of granulocytes to lymphocytes in children with severe pertussis and hyperleukopenia indicates a critical condition. Once routine treatment is ineffective and secondary organ dysfunction occurs in children with severe pertussis, ECMO can be considered a "salvage" supportive treatment method that endangers their lives.
期刊介绍：
Chinese Journal of Neurology was established in 1955, the predecessor of which is Chinese Journal of Neurology and Psychiatry. Chinese Journal of Neurology and Psychiatry has been indexed by MEDLINE until 1996, when it was divided into two journals, Chinese Journal of Neurology, and Chinese Journal of Psychiatry. Chinese Journal of Neurology is now indexed by EM, SCOPUS, AJ, WPRIM, CNKI, Wanfang Data, CSCD, etc. The impact factor of the journal is 2.755 in 2017, ranking the first among all neurological and psychological journals in China and among all the 142 medical journals published by the Chinese Medical Association. The journal is available both in print and online.
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