选择性腹腔镜胆囊切除术后端口感染的横断面比较研究

Y. Shakya, Samjhana Basnet, Latika Giri, Ajay K.C., R. Karmacharya
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引用次数: 0

摘要

背景:腹腔镜手术是一种微创手术,由于恢复率高、切口小而广受欢迎。腹腔镜手术后端口感染是一种罕见的并发症,增加了患者的发病率,也损害了外科医生的声誉。这取决于绝育和手术技术,这些技术随着时间的推移而有所改进。本研究的目的是评估预防性抗生素在预防腹腔镜胆囊切除术后端口部位感染中的作用。材料和方法:采用系统随机抽样方法,对2021年11月至2022年2月在三级护理医院接受选择性腹腔镜胆囊切除术的200名患者进行了横断面比较研究。在200名患者中,100名奇数患者服用了抗生素,100名偶数患者没有服用。两组的结果是根据端口感染进行测量的。结果:预防性使用抗生素组和不使用抗生素组的平均年龄分别为42.13(SD=14.41)和42.71(SD=14.29)岁。总患者的女性与男性比例为2.77。共有3例端口部位感染,接受抗生素(头孢噻肟)治疗的组有1例,而安慰剂组有2例。采用简单逻辑回归分析比较两组的结果(p>0.05),组织病理学诊断采用卡方检验,差异无统计学意义(χ2=0.99,p=0.80)。
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Port Site Infection after Elective Laparoscopic Cholecystectomy with or without the Use of Prophylactic Antibiotics: A Comparative Cross-Sectional Study
Background: Laparoscopic surgery, a minimally invasive procedure, has gained popularity due to early recovery rate and minimal incision. Port site infection following laparoscopic surgery is an infrequent complication, increasing patient's morbidity, and also damaging surgeon's reputation. It depends on sterilization and surgical techniques, which have improved with time. The aim of this study is to evaluate the role of prophylactic antibiotics in preventing port site infection after laparoscopic cholecystectomy. Materials and Methods: A comparative cross-sectional study on 200 patients undergoing elective laparoscopic cholecystectomy was conducted from November 2021 to February 2022 in tertiary care Hospital by using systematic random sampling.Among the 200 patients, 100 odd numbered patients were given antibiotics, and 100 even numbered patients were not. The outcome of the two groups was measured with regard to port site infection. Results: The mean age in prophylactic antibiotic receiving group and not receiving group was 42.13 (SD = 14.41) and 42.71(SD = 14.29) years, respectively. The female: male ratio for total patients was 2.77.There were three cases of port site infection in total, in group receiving antibiotics (Cefotaxime), there was one case, whereas in placebo group, there were two. Simple logistic regression was utilized to compare the results of two groups (p>0.05). Similarly, Chi-square test was applied to histopathology diagnosis, which showed no statistically significant difference (χ2 = 0.99, P = 0.80). Conclusion: Antibiotic prophylaxis does not lower the rate of infectious in patients undergoing elective laparoscopic cholecystectomy.
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