Stacey Lockyer, Marisol Aguirre, Louise Durrant, Bruno Pot, Kaori Suzuki
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引用次数: 0
摘要
摘要2018年4月,第九届国际养乐多研讨会在比利时根特举行。Wijmenga教授主讲了利用生物库了解肠道微生物群与健康之间的关系;Hill教授关于噬菌体与益生菌的相互作用。第一节课包括Plösch教授关于营养和环境因素的表观遗传学编程的讲座;Wilmes教授在微生物组研究中使用“组学”方法,Rescino教授在肠道血管屏障方面。第二部分探讨了干酪乳杆菌Shirota背后的证据,Nanno博士解释了免疫调节的可塑性,使菌株能够平衡免疫功能;Macnothan博士概述了它在肝硬化中的潜在治疗用途,Nishida教授详细介绍了它对压力下受试者的影响。在第三次会议上,Marchesi教授描述了宿主基因和肠道微生物群都可以在癌症中发挥作用;Bergheim教授强调了肠道和肝脏之间的串扰,Cani教授描述了肠道微生物群和内分泌系统之间的关系。最后一次会议探讨了益生菌机制,Lebeer教授剖析了进行机制研究的挑战;Wehkamp教授描述了粘膜防御系统,Van de Wiele教授详细介绍了体外模拟肠道微生物群的方法。
The role of probiotics on the roadmap to a healthy microbiota: a symposium report.
The ninth International Yakult Symposium was held in Ghent, Belgium in April 2018. Keynote lectures were from Professor Wijmenga on using biobanks to understand the relationship between the gut microbiota and health; and Professor Hill on phage-probiotic interactions. Session one included talks from Professor Plӧsch on epigenetic programming by nutritional and environmental factors; Professor Wilmes on the use of "omics" methodologies in microbiome research and Professor Rescigno on the gut vascular barrier. Session two explored the evidence behind Lactobacillus casei Shirota with Dr Nanno explaining the plasticity in immunomodulation that enables the strain to balance immune functions; Dr Macnaughtan outlining its potential therapeutic use in cirrhosis and Professor Nishida detailing effects in subjects under stress. The third session saw Professor Marchesi describing that both the host genes and the gut microbiota can play a role in cancer; Professor Bergheim highlighting crosstalk between the gut and the liver and Professor Cani describing the relationship between the gut microbiota and the endocrine system. The final session explored probiotic mechanisms, with Professor Lebeer dissecting the challenges in conducting mechanistic studies; Professor Wehkamp describing the mucosal defence system and Professor Van de Wiele detailing methods for modelling the gut microbiota in vitro.