基因工程藻类衍生生物活性化合物的潜在途径:影响参数、挑战和未来展望

IF 7.3 2区 生物学 Q1 PLANT SCIENCES Phytochemistry Reviews Pub Date : 2023-03-20 DOI:10.1007/s11101-023-09859-y
Richa Kothari, Har Mohan Singh, Rifat Azam, Kajol Goria, Anu Bharti, Anita Singh, Somvir Bajar, Ashish Pathak, A. K. Pandey, V. V. Tyagi
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引用次数: 2

摘要

随着人类生活水平的不断提高,对自然资源的需求也越来越大。藻类生物量已经成为从动物和植物中获得的传统资源的替代品。藻类含有丰富的可提取碳水化合物、蛋白质、脂质和其他有价值的生物活性化合物(BACs)。大量来源于藻类生物量的BACs包括长链多糖、脂肪酸,如单不饱和脂肪酸和多不饱和脂肪酸(MUFA和PUFA)、酚类和蛋白质。废水与藻类耦合进行资源回收,提取BACs可作为丰富的具有高工业价值的生物化学物质的来源,如色素、多糖、脂质、抗氧化剂和促生长化合物。提取的藻类BACs可以纳入许多化妆品,药品和营养保健品的制造。与需求相比,藻类产品的生产力和质量仍然很低。基因工程已经成为一种行之有效的方法,可以提高藻类产品的质量和数量,并为生物燃料和增值化学品生产提供更好的途径。目前,基因工程已经引起了研究人员的极大关注,并鼓励不断努力改善工业上可行的藻类物种,以满足未来的需求。本文重点介绍了从藻类和废水中提取BACs的广泛资源回收,藻类基因工程用于BACs,影响基因工程藻类的加工参数,与基因工程藻类相关的问题,以及未来的展望。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Potential avenue of genetic engineered algal derived bioactive compounds: influencing parameters, challenges and future prospects

The rising living standards of humans have a high demand for natural resources. Algal biomass has emerged as a substitute for conventional resources obtained from animals and plants. Compositionally, algae constitute extractable carbohydrates, proteins, lipids, and other valuable bioactive compounds (BACs) in abundance. BACs profusely derived from algal biomass include long-chain polysaccharides, fatty acids such as mono- and polyunsaturated fatty acids (MUFA and PUFA), phenols, and proteins. The coupling of wastewater with algae for resource recovery for the BACs extraction can serve as a source of plenteous biochemicals with high industrial values like pigments, polysaccharides, lipids, antioxidants, and growth-promoting compounds. Extracted algal BACs can incorporate in the manufacturing of numerous cosmetic products, pharmaceuticals, and nutraceuticals. The productivity and quality of algal produce are still low relative to their demand. Genetic engineering has emerged as a proven approach to enhance the quality and quantity of algal produces and provide a better avenue for biofuel and value-added chemicals productions. Currently, genetic engineering has grabbed significant attention from researchers, and continuous efforts are encouraged to improve industrially viable algal species that can satisfy future demand. This article focuses on the wide range of BACs derived from algae and wastewater for resource recovery, genetic engineering in algae for BACs, influencing processing parameters for genetic engineered algae, concerns associated with genetic engineered algae, and future perspective.

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来源期刊
Phytochemistry Reviews
Phytochemistry Reviews PLANT SCIENCES-
CiteScore
16.30
自引率
2.60%
发文量
54
审稿时长
2 months
期刊介绍: Phytochemistry Reviews is the sole review journal encompassing all facets of phytochemistry. It publishes peer-reviewed papers in six issues annually, including topical issues often stemming from meetings organized by the Phytochemical Society of Europe. Additionally, the journal welcomes original review papers that contribute to advancing knowledge in various aspects of plant chemistry, function, biosynthesis, effects on plant and animal physiology, pathology, and their application in agriculture and industry. Invited meeting papers are supplemented with additional review papers, providing a comprehensive overview of the current status across all areas of phytochemistry.
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