F. Pakdel, J. Pakdel, Ali Najmeddin, Afshin Peirovi, M. H. Nicknam, F. Dorkoosh
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A novel controlled release implant of insulin based on Poly (3- hydroxybutyrate-co-3-hydroxyvalerate) polymer prepared by extrusion process
Introduction Developing and designing an implant with a controlled release of active protein drugs has always been a challenge. In order to optimize and control the release of insulin in this project, the drug complexing mechanism was used by dextran sulfate sodium and PHBV (Poly (3-hydroxybutyrate-co-3-hydroxyvalerate)) polymer. Methods For this purpose
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