感染艾滋病毒的儿童和青少年的无症状疟疾寄生虫病

Q4 Medicine Sahel Medical Journal Pub Date : 2021-04-01 DOI:10.4103/smj.smj_20_19
S. Bello, E. Audu, I. Hassan, E. Abolodje, I. Bako
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引用次数: 0

摘要

背景:疟疾表现为危及生命的症状,导致住院,有时可能导致死亡。这在儿童中更具破坏性,因为严重疟疾后免疫系统受损导致儿童易受感染。人类免疫缺陷病毒(HIV)与疟疾的合并感染进一步损害了免疫系统并增加了脆弱性。在我国疟疾和艾滋病毒都流行的环境中,复方新诺明预防疟疾的效果还没有得到很好的评价。本研究旨在确定在我们医院接受治疗的艾滋病毒感染儿童和青少年中无症状疟疾的程度。研究设计:这是一项描述性横断面研究。材料和方法:一项前瞻性研究纳入了2-18岁感染艾滋病毒的儿童。采用非概率方便抽样方法招募符合条件的个体。通过问卷调查和患者病历收集部分数据。采集样本进行疟疾寄生虫显微镜检查。分析是使用统计软件包为社会科学版本20完成的。分类变量以百分比表示,使用卡方检验评估相关性;连续变量以均值和标准差表示,使用学生t检验检验两均值之间的相关性。结果:研究人群平均年龄为7.02±2.97岁。在这项研究的420名参与者中,有92人(45.7%)确诊患有疟疾。疟疾患者的性别、年龄组和病毒载量没有显著差异。结论:本研究地区疟疾合并HIV感染率较高。
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Asymptomatic malaria parasitaemia among HIV infected children and adolescents
Background: Malaria manifests with life-threatening manifestations resulting in hospital admissions and sometimes death may ensue. This is more devastating among children due to high susceptibility resulting from impaired immune system following severe malaria. Human immunodeficiency virus (HIV) coinfection with malaria further compromises the immune system and increases the vulnerability. The effect of co-trimoxazole prophylaxis in curtailing malaria has not being well evaluated in our environment where both malaria and HIV are endemic. This study sets out to determine the magnitude of asymptomatic malaria among HIV-infected children and adolescents receiving care at our facility. Study Design: This was a descriptive cross-sectional study. Materials and Methods: A prospective study among HIV-infected children aged 2–18 years was enrolled in our care. Nonprobability convenience sampling was used to recruit individuals who fulfilled the criteria. Questionnaire and patients' medical records were used to gather some data. A sample was taken for malaria parasite microscopy. The analysis was done using the Statistical Package for the Social Sciences version 20. Categorical variables were presented as percentages and association assessed using Chi-square test, whereas continuous variables were presented as mean and standard deviation, and the association between two means was checked using Student's t-test. Results: The mean age of the study population is 7.02 ± 2.97 years. Of the 420 participants in this study, 92 (45.7%) had confirmed malaria. There was no significant difference in the gender, age groups, and viral loads of patients with malaria. Conclusion: There is a high prevalence of malaria coinfection with HIV in this study.
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来源期刊
Sahel Medical Journal
Sahel Medical Journal Medicine-Medicine (all)
CiteScore
0.60
自引率
0.00%
发文量
5
审稿时长
47 weeks
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