从生物学角度解读心理治疗精神疾病

M. Binder
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摘要

由于精神驱动的精神症状和神经驱动的精神疾病症状之间缺乏明确的区别,确定哪些患者最适合接受心理治疗,哪些患者最好接受药物治疗,以及哪些患者最好同时接受药物治疗是每个行为健康临床医生面临的挑战。为了克服这一挑战,本文将讨论精神和大脑之间的解剖和功能关系,因为它与目前可用的各种治疗方案有关,并介绍一种开创性的新范式,旨在将精神疾病的治疗从基于症状的实践转变为基于病理学的实践。除了将精神疾病的评估和治疗与其他药物专业相提并论外,新范式开创了第一种客观的方法来区分基于生物学的精神症状和基于心理的精神症状。这一点至关重要,因为它有可能简化治疗,更好地确定治疗目标,并更准确地为治疗计划提供信息。它也有可能通过更好地解释心理治疗是如何工作的,药物治疗是如何运作的,以及这两种治疗模式如何互补或在某些情况下相互对抗,来改善患者的教育和治疗结果。除了所有这些优势之外,新的范式还提供了在精神症状开始之前就将其拒之门外的潜力。随着精神病和药物使用障碍的流行,这些期待已久的进展再及时不过了。
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Untangling Psychology from Biology in the Treatment of Psychiatric Disorders
Due to the lack of a clear distinction between mentally-driven psychiatric symptoms and neurologically-driven psychiatric symptoms, determining which patients would best be treated with psychotherapy, which patients would best be treated with pharmacotherapy, and which patients would best be treated with both is a challenge that every behavioral health clinician faces. In an effort to overcome this challenge, this article will discuss the anatomical and functional relationship between the mind and the brain as it relates to the various treatment options that are currently available and introduce a groundbreaking new paradigm that is destined to transform the treatment of mental illness from a symptom-based practice to a pathology-based practice. In addition to putting the assessment and treatment of mental illness on par with other medication specialties, the new paradigm ushers in the first objective way to distinguish biologically-based psychiatric symptoms from psychologically-based psychiatric symptoms. This is of critical importance because it has the potential streamline treatment, better define the target for treatment, and more accurately inform the planning of treatment. It also has the potential to improve patient education and treatment outcomes by better explaining how psychotherapy works, how pharmacotherapy works, and how these two treatment modalities can complement or, in some cases, antagonize each other. Beyond all of these advantages, the new paradigm offers the potential to ward off psychiatric symptoms before they even begin. With the prevalence of psychiatric and substance use disorders at epidemic proportions, these long-awaited advances could not be more timely.
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