术中神经生理监测对前庭神经鞘瘤术后面瘫预后的价值

Luis Torres-Carretero , Álvaro Otero-Rodríguez , María Victoria Alejos-Herrera , Gemma Vázquez-Casares , Andoni García-Martín , Patricia Alejandra Garrido-Ruiz
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引用次数: 0

摘要

背景与目的术中神经生理学监测可以预测前庭神经鞘瘤手术后面神经的功能状态。由于用于它的神经生理学方案具有很大的可变性,本研究的目的是确定我们的神经生病学方案的预后能力。材料和方法我们对2009年3月至2021年7月在萨拉曼卡神经外科手术的患者根据其术后即刻和术后一年的功能状态收集的神经生理学监测数据进行了统计分析。结果分析了51例年龄在46岁至63岁之间的患者(中位数:54)。研究面神经刺激强度阈值和皮质球诱发运动电位的变化,我们发现手术后临床状况良好和不良患者之间存在显著差异(分别为P=0.043和P=0.011)。最具辨别力的强度阈值为0.35 mA(灵敏度:85%;特异性:48%)。研究组在手术后一年没有发现统计学上的相关性。结论我们的术中监测方案使我们能够预测患者术后即刻的临床情况,并为患者及其亲属提供术后信息。然而,我们不能使用这些参数来预测手术后一年的功能状况,并在这方面做出临床决策。
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Utilidad de la monitorización neurofisiológica intraoperatoria como valor pronóstico de la parálisis facial posquirúrgica en schwannomas vestibulares

Background and objective

Intraoperative neurophysiological monitoring allows us to predict the functional status of the facial nerve after vestibular schwannoma surgery. Due to the great variability of the neurophysiological protocols used for it, the goal of this study is to determine the prognostic ability of our neurophysiological protocol.

Material and methods

We have performed a statistical analysis of the neurophysiological monitoring data collected from patients operated between March 2009 and July 2021 at the Neurosurgery Service of Salamanca according to their functional status, both in the immediate post-surgical period and one year after surgery.

Results

A number of 51 patients between 46 and 63 years old (median: 54) were analyzed. We have found significant differences studying the threshold value of the stimulation intensity of the facial nerve and the variation of the Cortico-bulbar Evoked Motor Potentials (P = 0.043 and P  = 0.011, respectively) between the patients with good and bad clinical situation after surgery. The most discriminating intensity threshold value was 0.35 mA (Sensitivity: 85%; Specificity: 48%). No statistical relationship was found in the study group one year after surgery.

Conclusions

Our intraoperative monitoring protocol allows us to predict the clinical situation of patients in the immediate postoperative period and improve information for the patient and her relatives after surgery. We cannot, however, use these parameters to predict the functional situation one year after surgery and make clinical decisions in this regard.

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