AMI in very young (aged ≤ 35 years) Bangladeshi patients: Risk factors & coronary angiographic profile

Background

Coronary artery disease is a devastating disease precisely because an otherwise healthy person in the prime of life may die or become disabled without warning. When the afflicted individual is under the age of 35, the tragic consequences for family, friends, and occupation are particularly catastrophic and unexpected. The purpose of the present study was to assess the risk factors, angiographic profile, and in-hospital outcome of very young patients (aged ≤ 35 years) with first acute myocardial infarction (AMI).

Methods

A cross-sectional study was conducted involving 266 young (≤ 35 years) patients with clinical diagnosis of AMI. They were studied for risk factors, clinical characteristics, and in-hospital outcome between February 2012 and October 2014 at the NHFH&RI, Dhaka, Bangladesh. Coronary angiography was done in 230 patients.

Results

The mean age of patients was 31.19 ± 3.81 years; 94.7% were male. The major risk factor was smoking, followed by dyslipidemia, family history of ischemic heart disease. The most common anatomical location for the MI was the anterior wall. Significant coronary artery disease was found in 83.04% patients, 7.39% patients had normal coronaries. Most patients had single vessel disease followed by double-vessel disease. Left anterior descending was the commonest vessel involved followed by left circumflex artery. In-hospital mortality was 2.3%.

Conclusion

AMI in very young almost exclusively occurs in male and smoking was the most common risk factor. Acute anterior MI owing to occluded left anterior descending artery was more frequent. Very young patients with an AMI have a favorable in-hospital mortality.