预后营养指数在预测COVID-19患者预后中的价值

Q4 Medicine 武汉大学学报(医学版) Pub Date : 2021-01-01 DOI:10.14188/j.1671-8852.2020.0304

D. Xie, D. Wen, Y. Liu

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摘要

目的:探讨2019冠状病毒病(COVID-19)住院患者预后营养指数(PNI)与生存率的关系。方法:采用回顾性研究方法，收集武汉市金银潭医院新冠肺炎患者资料。PNI是根据血液检测结果计算的。结果:重症患者PNI值显著低于轻症组(29.7比46.8,P<0.001)，死亡组与生存组PNI值也有显著差异(28.15比38.1,P<0.001)。ROC分析显示PNI对重症COVID-19的诊断有重要意义，可作为重症患者生存的独立预测因子(P<0.01)。结论:低预后营养指数与SARS-CoV-2重症肺炎患者预后不良显著相关。©2021，武汉大学医学杂志编辑委员会。版权所有。

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Values of prognostic nutritional index in predicting the outcomes of COVID-19 patients

Objective: To assess the association between prognostic nutritional index (PNI) and survival in patients hospitalized for coronavirus disease 2019 (COVID-19). Methods: In this retrospective study, we collected data of COVID-19 patients in Wuhan Jinyintan Hospital. The PNI were calculated on the basis of blood test results. Results: The PNI in severe patients was significantly lower than that in mild group (29.7 versus 46.8, P<0.001);while the PNI value also showed signifcant difference between death group and survival group (28.15 versus 38.1, P<0.001). ROC analysis revealed that PNI was important for the diagnosis of severe COVID-19, and could be used as an independent predictor of survival in severe patients (P<0.01). Conclusion: Low prognostic nutritional index was remarkably associated with a poor prognosis in severe patients with SARS-CoV-2 pneumonia. © 2021, Editorial Board of Medical Journal of Wuhan University. All right reserved.

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