Initial chest CT imaging features of COVID-19 and their relation to clinical types

Objective: To investigate the initial chest CT imaging features and clinical types of patients with COVID-19. Methods: A total 165 patients with COVID-19 were retrospectively analyzed according to different age groups and different clinical classifications. Results: There were statistically significant differences in involvement sites, involvement range, lesion distribution and largest diameter of the lesions in COVID-19 patients among different age groups. Logistic regression analysis of age between normal type group and severe type group showed statistical significance (P<0.05). The maximum sensitivity and specificity were 64.20% and 69.00%. The corresponding age threshold was 50.5 years old. Conclusion: The main manifestations of initial chest CT in COVID-19 patients were ground-glass opacities, most often involving the posterior basal segment of the lower lung. Single site involvement was more common in 17-35 years patients. Most of the lesions were distributed around the subpleural and bronchovascular bundle in 36-90 years patients, involving both lungs and reaching more than two pulmonary lobes. For the COVID-19 patients with diabetes, hypertension, or older than 50.5 years, early diagnosis, isolation and treatment are necessary, and the changes of their conditions should be closely mornitored. © 2021, Editorial Board of Medical Journal of Wuhan University. All right reserved.