{"title":"TRAB测量:准备好迎接黄金时段了吗?","authors":"C. Lau, T. Aw","doi":"10.16966/2380-548x.157","DOIUrl":null,"url":null,"abstract":"generation TRAb assays. Tozzoli R, et al. [7] compared an automated 3rd generation TRAb (RAD 120; Radim, Pomezia, Italy) against a second 2nd generation TRAb immunoassay (Lumitest TRAK human; Brahms, Berlin, Germany). The ROC plot of the 3rd generation assay was excellent (AUC 0.994), with a lower optimal threshold of 1.25 U/L compared to second generation value of 1.99 U/l. The 3rd generation assay had a higher sensitivity of 97.6% versus 95.1% for the 2nd generation assay. The 3rd generation assay also had greater analytical precision with a faster turnaround time.","PeriodicalId":73446,"journal":{"name":"International journal of endocrinology and metabolic disorders","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"TRAB Measurements: Ready for Prime Time?\",\"authors\":\"C. Lau, T. Aw\",\"doi\":\"10.16966/2380-548x.157\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"generation TRAb assays. Tozzoli R, et al. [7] compared an automated 3rd generation TRAb (RAD 120; Radim, Pomezia, Italy) against a second 2nd generation TRAb immunoassay (Lumitest TRAK human; Brahms, Berlin, Germany). The ROC plot of the 3rd generation assay was excellent (AUC 0.994), with a lower optimal threshold of 1.25 U/L compared to second generation value of 1.99 U/l. The 3rd generation assay had a higher sensitivity of 97.6% versus 95.1% for the 2nd generation assay. The 3rd generation assay also had greater analytical precision with a faster turnaround time.\",\"PeriodicalId\":73446,\"journal\":{\"name\":\"International journal of endocrinology and metabolic disorders\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International journal of endocrinology and metabolic disorders\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.16966/2380-548x.157\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of endocrinology and metabolic disorders","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.16966/2380-548x.157","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
generation TRAb assays. Tozzoli R, et al. [7] compared an automated 3rd generation TRAb (RAD 120; Radim, Pomezia, Italy) against a second 2nd generation TRAb immunoassay (Lumitest TRAK human; Brahms, Berlin, Germany). The ROC plot of the 3rd generation assay was excellent (AUC 0.994), with a lower optimal threshold of 1.25 U/L compared to second generation value of 1.99 U/l. The 3rd generation assay had a higher sensitivity of 97.6% versus 95.1% for the 2nd generation assay. The 3rd generation assay also had greater analytical precision with a faster turnaround time.
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