S. Makarova, E. E. Emelyashenkov, A. Fisenko, N. Murashkin, M. Vershinina, E. Semikina, D. S. Yasakov, M. Snovskaya, O. Ereshko, A. Galimova
{"title":"严重特应性皮炎和食物过敏儿童的人体测量参数和营养状况","authors":"S. Makarova, E. E. Emelyashenkov, A. Fisenko, N. Murashkin, M. Vershinina, E. Semikina, D. S. Yasakov, M. Snovskaya, O. Ereshko, A. Galimova","doi":"10.20953/1727-5784-2022-5-16-26","DOIUrl":null,"url":null,"abstract":"Objective. To assess the nutritional status and factors affecting it in children with severe atopic dermatitis (AD) and food allergy (FA). Patients and methods. This single-center, observational, cross-sectional, uncontrolled, retrospective study enrolled 315 children aged between 1 month and 17 years 11 months with severe AD and FA. Standard anthropometric parameters were measured and calculated, including WAZ (weight-for-age Z-score), HAZ (height-for-age Z-score), and BAZ (BMI-for-age Z-score). Patients’ medical histories were examined, and the levels of total IgE and specific IgE to food allergens, hemoglobin, ferritin, iron, and vitamin D were evaluated. Results. On average, anthr opometric parameters in the examined patients were below the reference values. Failure to thrive of mild degree was detected in 27.6% of children, moderate degree in 13.7%, and severe degree in 2,2%. The frequency of overweight and obesity was 9.5% and 3.8%, respectively. A correlation was found between HAZ and children’s age (r = 0.21, p = 0.015) and the number of excluded food groups (r = -1.66, p = 0.031), and between BAZ and the number of excluded food groups (r = -1.39, p = 0.019). HAZ (p = 0.014) and BAZ (p = 0.017) values were lower in children following a dairy-free diet than in children on other types of elimination diets. At the same time, BAZ was higher in children who did not strictly follow the diet than in those who did (p = 0.011). There was a correlation between BAZ and vitamin D levels (r = 0.29, p = 0.012). Formulas based on extensive hydrolyzed protein and free aminoacides reduced severity and frequency of failure to thrive in management children with CMPA. Conclusion. Children with severe AD and FA require careful planning of their diets to reduce the risk of failure to thrive. It is necessary to study the influence of dietary composition and eating behavior of patients on their nutritional status. Key words: children, atopic dermatitis, nutritional status, elimination diet, food allergy, physical development, vitamin D","PeriodicalId":53444,"journal":{"name":"Voprosy Detskoi Dietologii","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Anthropometric parameters and nutritional status in children with severe atopic dermatitis and food allergy\",\"authors\":\"S. Makarova, E. E. Emelyashenkov, A. Fisenko, N. Murashkin, M. Vershinina, E. Semikina, D. S. Yasakov, M. Snovskaya, O. Ereshko, A. Galimova\",\"doi\":\"10.20953/1727-5784-2022-5-16-26\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective. To assess the nutritional status and factors affecting it in children with severe atopic dermatitis (AD) and food allergy (FA). Patients and methods. This single-center, observational, cross-sectional, uncontrolled, retrospective study enrolled 315 children aged between 1 month and 17 years 11 months with severe AD and FA. Standard anthropometric parameters were measured and calculated, including WAZ (weight-for-age Z-score), HAZ (height-for-age Z-score), and BAZ (BMI-for-age Z-score). Patients’ medical histories were examined, and the levels of total IgE and specific IgE to food allergens, hemoglobin, ferritin, iron, and vitamin D were evaluated. Results. On average, anthr opometric parameters in the examined patients were below the reference values. Failure to thrive of mild degree was detected in 27.6% of children, moderate degree in 13.7%, and severe degree in 2,2%. The frequency of overweight and obesity was 9.5% and 3.8%, respectively. A correlation was found between HAZ and children’s age (r = 0.21, p = 0.015) and the number of excluded food groups (r = -1.66, p = 0.031), and between BAZ and the number of excluded food groups (r = -1.39, p = 0.019). HAZ (p = 0.014) and BAZ (p = 0.017) values were lower in children following a dairy-free diet than in children on other types of elimination diets. At the same time, BAZ was higher in children who did not strictly follow the diet than in those who did (p = 0.011). There was a correlation between BAZ and vitamin D levels (r = 0.29, p = 0.012). Formulas based on extensive hydrolyzed protein and free aminoacides reduced severity and frequency of failure to thrive in management children with CMPA. Conclusion. Children with severe AD and FA require careful planning of their diets to reduce the risk of failure to thrive. It is necessary to study the influence of dietary composition and eating behavior of patients on their nutritional status. Key words: children, atopic dermatitis, nutritional status, elimination diet, food allergy, physical development, vitamin D\",\"PeriodicalId\":53444,\"journal\":{\"name\":\"Voprosy Detskoi Dietologii\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Voprosy Detskoi Dietologii\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.20953/1727-5784-2022-5-16-26\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Voprosy Detskoi Dietologii","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.20953/1727-5784-2022-5-16-26","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
摘要
目标。探讨严重特应性皮炎(AD)和食物过敏(FA)患儿的营养状况及其影响因素。患者和方法。这项单中心、观察性、横断面、非对照、回顾性研究招募了315名患有严重AD和FA的儿童,年龄在1个月至17岁11个月之间。测量和计算标准人体测量参数,包括WAZ(体重年龄z分数)、HAZ(身高年龄z分数)和BAZ (bmi年龄z分数)。检查患者的病史,评估总IgE和对食物过敏原、血红蛋白、铁蛋白、铁和维生素D的特异性IgE水平。结果。平均而言,检查患者的验光参数低于参考值。轻度发育不良患儿占27.6%,中度发育不良患儿占13.7%,重度发育不良患儿占2.2%。超重和肥胖的频率分别为9.5%和3.8%。HAZ与儿童年龄(r = 0.21, p = 0.015)、被排除食物组数(r = -1.66, p = 0.031)、BAZ与被排除食物组数(r = -1.39, p = 0.019)呈正相关。无乳制品饮食的儿童HAZ (p = 0.014)和BAZ (p = 0.017)值低于其他类型消除饮食的儿童。与此同时,未严格遵循饮食的儿童的BAZ高于严格遵循饮食的儿童(p = 0.011)。BAZ与维生素D水平存在相关性(r = 0.29, p = 0.012)。基于广泛水解蛋白和游离氨基酸的配方降低了CMPA患儿生长失败的严重程度和频率。结论。患有严重AD和FA的儿童需要仔细规划他们的饮食,以减少无法茁壮成长的风险。因此,有必要研究患者饮食组成和饮食行为对其营养状况的影响。关键词:儿童,特应性皮炎,营养状况,消除饮食,食物过敏,身体发育,维生素D
Anthropometric parameters and nutritional status in children with severe atopic dermatitis and food allergy
Objective. To assess the nutritional status and factors affecting it in children with severe atopic dermatitis (AD) and food allergy (FA). Patients and methods. This single-center, observational, cross-sectional, uncontrolled, retrospective study enrolled 315 children aged between 1 month and 17 years 11 months with severe AD and FA. Standard anthropometric parameters were measured and calculated, including WAZ (weight-for-age Z-score), HAZ (height-for-age Z-score), and BAZ (BMI-for-age Z-score). Patients’ medical histories were examined, and the levels of total IgE and specific IgE to food allergens, hemoglobin, ferritin, iron, and vitamin D were evaluated. Results. On average, anthr opometric parameters in the examined patients were below the reference values. Failure to thrive of mild degree was detected in 27.6% of children, moderate degree in 13.7%, and severe degree in 2,2%. The frequency of overweight and obesity was 9.5% and 3.8%, respectively. A correlation was found between HAZ and children’s age (r = 0.21, p = 0.015) and the number of excluded food groups (r = -1.66, p = 0.031), and between BAZ and the number of excluded food groups (r = -1.39, p = 0.019). HAZ (p = 0.014) and BAZ (p = 0.017) values were lower in children following a dairy-free diet than in children on other types of elimination diets. At the same time, BAZ was higher in children who did not strictly follow the diet than in those who did (p = 0.011). There was a correlation between BAZ and vitamin D levels (r = 0.29, p = 0.012). Formulas based on extensive hydrolyzed protein and free aminoacides reduced severity and frequency of failure to thrive in management children with CMPA. Conclusion. Children with severe AD and FA require careful planning of their diets to reduce the risk of failure to thrive. It is necessary to study the influence of dietary composition and eating behavior of patients on their nutritional status. Key words: children, atopic dermatitis, nutritional status, elimination diet, food allergy, physical development, vitamin D
期刊介绍:
The scientific journal Voprosy Detskoi Dietologii is included in the Scopus database. Publisher country is RU. The main subject areas of published articles are Food Science, Pediatrics, Perinatology, and Child Health, Nutrition and Dietetics, Клиническая медицина.