{"title":"在过去十年中,一些治疗类别药物的强制降解分析的包容性探索","authors":"T. Narsinghani, J. Tuteja, Anamika Singh","doi":"10.4103/jss.jss_244_22","DOIUrl":null,"url":null,"abstract":"In the pharmaceutical industry, forced degradation tests are used to assess the stability of drug samples. Examining degradation products under stress is beneficial for determining degradation pathways as well as designing and validating appropriate analytical techniques. Forced degradation experiments reveal the molecule's chemical behavior, which aids formulation and packaging creation. The current review examines the forced degradation of a variety of therapeutic classes of medications, including anticancer, antihypertensive, antiviral, CNS pharmaceuticals, and other miscellaneous drugs. During forced degradation analysis, the study examines the degradation behavior of several medications from the abovementioned categories. The findings will likely aid researchers in determining the degradation process of related drugs belonging to the same category.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":"1 1","pages":"312 - 344"},"PeriodicalIF":0.1000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"An inclusive exploration of forced degradation analysis of some therapeutic categories of drugs in the last decade\",\"authors\":\"T. Narsinghani, J. Tuteja, Anamika Singh\",\"doi\":\"10.4103/jss.jss_244_22\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In the pharmaceutical industry, forced degradation tests are used to assess the stability of drug samples. Examining degradation products under stress is beneficial for determining degradation pathways as well as designing and validating appropriate analytical techniques. Forced degradation experiments reveal the molecule's chemical behavior, which aids formulation and packaging creation. The current review examines the forced degradation of a variety of therapeutic classes of medications, including anticancer, antihypertensive, antiviral, CNS pharmaceuticals, and other miscellaneous drugs. During forced degradation analysis, the study examines the degradation behavior of several medications from the abovementioned categories. The findings will likely aid researchers in determining the degradation process of related drugs belonging to the same category.\",\"PeriodicalId\":55681,\"journal\":{\"name\":\"Journal of the Scientific Society\",\"volume\":\"1 1\",\"pages\":\"312 - 344\"},\"PeriodicalIF\":0.1000,\"publicationDate\":\"2023-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the Scientific Society\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/jss.jss_244_22\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Scientific Society","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/jss.jss_244_22","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
An inclusive exploration of forced degradation analysis of some therapeutic categories of drugs in the last decade
In the pharmaceutical industry, forced degradation tests are used to assess the stability of drug samples. Examining degradation products under stress is beneficial for determining degradation pathways as well as designing and validating appropriate analytical techniques. Forced degradation experiments reveal the molecule's chemical behavior, which aids formulation and packaging creation. The current review examines the forced degradation of a variety of therapeutic classes of medications, including anticancer, antihypertensive, antiviral, CNS pharmaceuticals, and other miscellaneous drugs. During forced degradation analysis, the study examines the degradation behavior of several medications from the abovementioned categories. The findings will likely aid researchers in determining the degradation process of related drugs belonging to the same category.