K. Okuda, T. Hirota, M. Hirobe, T. Nagano, M. Mochizuki, T. Mashino
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Synthesis of Various Water-Soluble G60 Derivatives and Their Superoxide-Quenching Activity
Abstract In order to examine the utility of fullerene as a medicinal application, we evaluated the reaction between fullerene derivatives and active oxygen species in vitro. This paper describes the synthesis of various water-soluble C60 derivatives (cationic and anionic) and evaluation of their superoxide (O2 −) quenching activity. Cationic C60 derivatives showed fairly high efficiency.