甲状腺髓样癌合并肾细胞癌1例

Yu. A. Dolinskaya, S. Shevchenko, V. Maksimov, E. Voropaeva, O. Rymar
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引用次数: 0

摘要

接受第一次恶性肿瘤治疗的患者在其以后的生活中仍处于患第二次原发性肿瘤的风险增加的组中。一个罕见的病例甲状腺髓样癌和肾细胞癌的肾脏是描述在一个病人。甲状腺髓样癌是一种罕见病。患者及其一线亲属接受了分子基因检测,排除了遗传性髓样癌的存在。观察中发现恶性肾形成,并予手术治疗。该患者由于治疗和监测没有甲状腺癌和肾癌进展的数据,对伴随疾病的补偿已经实现。当观察甲状腺髓样癌患者时,有必要使用现有的现代诊断工具,包括正电子发射断层扫描,因为患者在整个后续生活中仍然处于疾病进展和第二肿瘤发展风险增加的组中。此外,该病例清楚地说明了常规研究降钙素作为甲状腺髓样癌进展的诊断标志物的必要性。
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Combination of medullary thyroid cancer and renal cell carcinoma in one patient
Patients who received treatment for the first malignant neoplasm remain in the group at increased risk of developing a second primary tumor throughout their later life. A rare case of medullary thyroid cancer and renal cell carcinoma of the kidney is described in one patient. Medullary thyroid cancer is an orphan disease. The patient and his first-line relatives underwent molecular-genetic testing, the presence of a hereditary form of medullary cancer was excluded. During the observation, malignant kidney formation was detected, and surgical treatment was performed. The patient because of treatment and surveillance does not have data for the progression of thyroid cancer and kidney cancer, compensation for concomitant diseases has been achieved. When observing patients with medullary thyroid cancer, it is necessary to use the existing modern diagnostic arsenal, including positron emission tomography, since patients remain in the group at increased risk of disease progression and development of the second tumor throughout the entire subsequent life. In addition, this case clearly illustrates the need for a routine study of calcitonin as a diagnostic marker for the progression of medullary thyroid cancer.
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