H. S. Yuwono, M. Putri, W. Purbaningsih, N. M. Marsya, S. A. Sumantri
{"title":"通过测定成纤维细胞培养物中TNF-1和bFGF，对比罗布斯塔咖啡水提物与新霉素-杆菌肽对伤口愈合的影响","authors":"H. S. Yuwono, M. Putri, W. Purbaningsih, N. M. Marsya, S. A. Sumantri","doi":"10.18502/kls.v7i5.12519","DOIUrl":null,"url":null,"abstract":"Coffee grounds have been used to dress wounds for more than 100 years, with excellent results. The wound heals with an acceptable scar. This study aims to compare coffee extract to neomycin-bacitracin in cell migration. Compared to the antibiotic neomycin-bacitracin powder group and control group in scar tissue formation, the Robusta coffee powder extract measured positively on Transforming Growth Factor and Basic Fibroblast Growth Factor markers. This study emphasizes the ability of coffee to heal wounds without causing excessive scarring. Coffee is proven to have better wound healing capabilities than Neomycin-Bacitracin. \nKeywords: coffee grounds, fibroblast cell-line, Transforming Growth Factor, basic Fibroblast Growth Factor","PeriodicalId":17898,"journal":{"name":"KnE Life Sciences","volume":"23 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"The Effect of Aqueous Extract of Robusta Coffee Compared to Neomycin-Bacitracin on Wound Healing by Measuring TNF-1 and bFGF in Fibroblast Cell Cultures\",\"authors\":\"H. S. Yuwono, M. Putri, W. Purbaningsih, N. M. Marsya, S. A. Sumantri\",\"doi\":\"10.18502/kls.v7i5.12519\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Coffee grounds have been used to dress wounds for more than 100 years, with excellent results. The wound heals with an acceptable scar. This study aims to compare coffee extract to neomycin-bacitracin in cell migration. Compared to the antibiotic neomycin-bacitracin powder group and control group in scar tissue formation, the Robusta coffee powder extract measured positively on Transforming Growth Factor and Basic Fibroblast Growth Factor markers. This study emphasizes the ability of coffee to heal wounds without causing excessive scarring. Coffee is proven to have better wound healing capabilities than Neomycin-Bacitracin. \\nKeywords: coffee grounds, fibroblast cell-line, Transforming Growth Factor, basic Fibroblast Growth Factor\",\"PeriodicalId\":17898,\"journal\":{\"name\":\"KnE Life Sciences\",\"volume\":\"23 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-12-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"KnE Life Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18502/kls.v7i5.12519\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"KnE Life Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18502/kls.v7i5.12519","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The Effect of Aqueous Extract of Robusta Coffee Compared to Neomycin-Bacitracin on Wound Healing by Measuring TNF-1 and bFGF in Fibroblast Cell Cultures
Coffee grounds have been used to dress wounds for more than 100 years, with excellent results. The wound heals with an acceptable scar. This study aims to compare coffee extract to neomycin-bacitracin in cell migration. Compared to the antibiotic neomycin-bacitracin powder group and control group in scar tissue formation, the Robusta coffee powder extract measured positively on Transforming Growth Factor and Basic Fibroblast Growth Factor markers. This study emphasizes the ability of coffee to heal wounds without causing excessive scarring. Coffee is proven to have better wound healing capabilities than Neomycin-Bacitracin.
Keywords: coffee grounds, fibroblast cell-line, Transforming Growth Factor, basic Fibroblast Growth Factor
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