具有血管顺应性和运动的人体主动脉生理逼真模型中血流的数值模拟

Suo Jin, J. Oshinski, D. Giddens
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引用次数: 0

摘要

除了血管几何形状外,血管顺应性和运动是影响动脉血流模式的重要因素。这一重要性已经在冠状动脉血流的研究中被几位研究者证实。对于像主动脉这样的大血管,由于其运动幅度相对较小且运动轨迹复杂,其影响尚不清楚。本研究利用磁共振(MR)图像重建计算流体动力学(CFD)主动脉模型,并利用MRI获得主动脉血流图和壁壁运动数据。在一些简化的假设下,这些数据被用来控制在计算模拟过程中具有移动壁和网格的主动脉模型。CFD模拟结果显示升主动脉内的血流形态与MRI结果相似,验证了模型重建和模拟的合理性。
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Numerical Simulation of Flow in a Physiologically Realistic Model of the Human Aorta With Vessel Compliance and Movement
Vessel compliance and movement are important factors influencing blood flow patterns in arteries in addition to vessel geometry. This importance has been previously demonstrated in the study of coronary artery flow by several investigators. For large vessels such as the aorta, the effects are less well understood because its movement magnitude is relatively small and the movement trace is complex. In this study, a computational fluid dynamics (CFD) aorta model was reconstructed from magnetic resonance (MR) images, and MRI was used to obtain aortic flow mapping and wall movement data. Under some simplifying assumptions, the data were used to control an aorta model that has moving wall and meshes during a computational simulation. The results of the CFD simulation show similar flow patterns as the MRI results in the ascending aorta, verifying that the model reconstruction and simulation are reasonable.
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