纳米给药系统:综述

Valli Nachiyar Syam Kumar, S. Sunkar, K. S, Jayshree Nellore
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引用次数: 0

摘要

医学纳米技术正在成为一个具有挑战性的领域,涵盖了新的生物医学应用,如药物输送、治疗、纳米诊断、药物控制释放、再生医学和疾病预防。纳米技术领域的最新发展使纳米结构能够克服与药物递送相关的问题,使其成为具有减少副作用和最佳治疗效果的位点特异性药物递送剂。这些纳米药物传递系统被设计成这样一种方式,它们可以突破生物屏障,以特定位点的方式传递药物。它们通过增加药物的稳定性和水溶性以及增加这些纳米药物复合物被细胞和组织吸收的速度来增强药物的有效性。树状大分子、纳米晶体、纳米聚合物NPs和脂质体是未来的纳米药物递送系统。智能聚合物是未来的药物输送系统,具有尖端的精确技术,分别用于基于温度、pH、光响应、导电和磁响应的智能聚合物的有效细胞靶向。本文综述了各种纳米结构及其在药物传递中的应用。
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Nano Drug Delivery Systems: A Mini-review
Medical nanotechnology is surfacing as a challenging arena covering new biomedical applications, such as drug delivery, treatment, nano diagnosis, controlled drug release, regenerative medicine, and disease prevention. The recent developments in the field of Nanotechnology have enabled the nanostructures to overcome the problems associated with drug delivery making them the promising agents for site-specific drug delivery with reduced side effects and the best treatment outcome. These nanodrug delivery systems are designed in such a way that they can breach the biological barrier and delivery the drug in a site-specific manner. They enhance the effectiveness of drugs by increasing the stability and water solubility of drugs and by increasing the rate at which these nano drug complexes are taken up by the cells and tissues. Dendrimers, nanocrystals, nano-polymer NPs, and liposomes are futuristic nano-based drug delivery systems. Smart polymers are future drug-delivery systems with cutting-edge precise technology that are employed in effective cellular targeting based on temperature, pH, photoresponsive, conductive and magnetic responsive smart polymers, respectively. This review provides a comprehensive view of various nanostructures and their application in drug delivery.
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来源期刊
Nanoscience and Nanotechnology - Asia
Nanoscience and Nanotechnology - Asia Engineering-Engineering (all)
CiteScore
1.90
自引率
0.00%
发文量
35
期刊介绍: Nanoscience & Nanotechnology-Asia publishes expert reviews, original research articles, letters and guest edited issues on all the most recent advances in nanoscience and nanotechnology with an emphasis on research in Asia and Japan. All aspects of the field are represented including chemistry, physics, materials science, biology and engineering mainly covering the following; synthesis, characterization, assembly, theory, and simulation of nanostructures (nanomaterials and assemblies, nanodevices, nano-bubbles, nano-droplets, nanofluidics, and self-assembled structures), nanofabrication, nanobiotechnology, nanomedicine and methods and tools for nanoscience and nanotechnology.
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