山腊芒果叶提取物降血糖作用的研究

T. Nguyen Duc, Trang Nguyen Hoang Thu, Van Anh Nguyen Thi
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引用次数: 0

摘要

以60%乙醇为溶剂,用索氏法提取芒果叶,减压蒸馏脱除溶剂。结果表明,在使用最大允许剂量时,没有小鼠死亡。对糖尿病小白鼠的降糖作用实验得到的结果是:以500 mg/kg的剂量治疗效果最好,甚至略优于阳性对照药物格列齐特,3天后血糖水平立即下降。21 d后降至52.5%,血糖指标恢复正常。这是利用植物源性药物,特别是芒果叶的新方向。
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Study on the hypoglycemic effect of mango leaf extract grown in Son La
Mango leaves were extracted by Soxhlet with 60% ethanol, the obtained solution was distilled to remove the solvent under reduced pressure. The results showed that when using the maximum allowable dose, there were no dead mice. Experimenting on blood glucose-lowering effects on diabetic white mice obtained the results: with a dose of 500 mg/kg giving the best therapeutic effect, even slightly better than the positive control drug gliclazide, the blood glucose level decreased immediately after three days. After 21 days reduced to 52.5% and brought the blood glucose index to normal. This is a new direction in the use of drugs of plant origin in general and Mango leaves in particular.
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